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The errors occurring in DNA-based storage are correlated in nature, which is a direct consequence of the synthesis and sequencing processes. In this paper, we consider the memory-$k$ nanopore channel model recently introduced by Hamoum et…

Information Theory · Computer Science 2023-03-27 Issam Maarouf , Eirik Rosnes , Alexandre Graell i Amat

In the usual trace reconstruction problem, the goal is to exactly reconstruct an unknown string of length $n$ after it passes through a deletion channel many times independently, producing a set of traces (i.e., random subsequences of the…

Data Structures and Algorithms · Computer Science 2020-12-17 Sami Davies , Miklos Z. Racz , Cyrus Rashtchian , Benjamin G. Schiffer

Quantum Random Access Memory (QRAM) is a critical component for loading classical data into quantum computers. While constructing a practical QRAM presents several challenges, including the impracticality of an infinitely large QRAM size…

We consider query-based data acquisition and the corresponding information recovery problem, where the goal is to recover $k$ binary variables (information bits) from parity measurements of those variables. The queries and the corresponding…

Information Theory · Computer Science 2018-01-03 Hye Won Chung , Ji Oon Lee , Alfred O. Hero

We study the theoretical problem of synthesizing multiple DNA strands under spatial constraints, motivated by large-scale DNA synthesis technologies. In this setting, strands are arranged in an array and synthesized according to a fixed…

Information Theory · Computer Science 2026-01-14 Boaz Moav , Ryan Gabrys , Eitan Yaakobi

In this paper, we consider a concatenated coding based class of DNA storage codes in which the selected molecules are constrained to be taken from an ``inner'' codebook associated with the sequencing channel. This codebook is used in a…

Information Theory · Computer Science 2025-06-19 Yan Hao Ling , Jonathan Scarlett

Due to its longevity and enormous information density, DNA is an attractive medium for archival storage. In this work, we study the fundamental limits and tradeoffs of DNA-based storage systems under a simple model, motivated by current…

Information Theory · Computer Science 2017-05-16 Reinhard Heckel , Ilan Shomorony , Kannan Ramchandran , David N. C. Tse

DNA, with remarkable properties of high density, durability, and replicability, is one of the most appealing storage media. Emerging DNA storage technologies use composite DNA letters, where information is represented by probability…

Information Theory · Computer Science 2025-03-26 Wenkai Zhang , Zhiying Wang

We consider the task of assigning unique integers to a group of processes in an asynchronous distributed system of a total of $n$ processes prone to crashes that communicate through shared read-write registers. In the Renaming problem, an…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-01 Bogdan S. Chlebus , Dariusz R. Kowalski

DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting…

Information Theory · Computer Science 2023-10-04 Jin Sima , Netanel Raviv , Moshe Schwartz , Jehoshua Bruck

Let $\mathcal{D}$ be a collection of $D$ documents, which are strings over an alphabet of size $\sigma$, of total length $n$. We describe a data structure that uses linear space and and reports $k$ most relevant documents that contain a…

Data Structures and Algorithms · Computer Science 2013-08-02 Gonzalo Navarro , Yakov Nekrich

DNA-based data storage has been attracting significant attention due to its extremely high data storage density, low power consumption, and long duration compared to conventional data storage media. Despite the recent advancements in DNA…

Information Theory · Computer Science 2024-11-12 Yi Ding , Xuan He , Tuan Thanh Nguyen , Wentu Song , Zohar Yakhini , Eitan Yaakobi , Linqiang Pan , Xiaohu Tang , Kui Cai

Min-entropy sampling gives a bound on the min-entropy of a randomly chosen subset of a string, given a bound on the min-entropy of the whole string. K\"onig and Renner showed a min-entropy sampling theorem that holds relative to quantum…

Quantum Physics · Physics 2011-07-18 Jürg Wullschleger

We formulate and analyze a generic sequential resource access problem arising in a variety of engineering fields, where a user disposes a number of heterogeneous computing, communication, or storage resources, each characterized by the…

Networking and Internet Architecture · Computer Science 2020-12-08 Lin Chen , Anastasios Giovanidis , Wei Wang , Lin Shan

The prevalent technique for DNA sequencing consists of two main steps: shotgun sequencing, where many randomly located fragments, called reads, are extracted from the overall sequence, followed by an assembly algorithm that aims to…

Genomics · Quantitative Biology 2016-01-28 Shirshendu Ganguly , Elchanan Mossel , Miklos Z. Racz

The maximum coverage problem is to select $k$ sets from a collection of sets such that the cardinality of the union of the selected sets is maximized. We consider $(1-1/e-\epsilon)$-approximation algorithms for this NP-hard problem in three…

Data Structures and Algorithms · Computer Science 2024-03-22 Amit Chakrabarti , Andrew McGregor , Anthony Wirth

Randomised algorithms often employ methods that can fail and that are retried with independent randomness until they succeed. Randomised data structures therefore often store indices of successful attempts, called seeds. If $n$ such seeds…

Data Structures and Algorithms · Computer Science 2025-07-03 Hans-Peter Lehmann , Peter Sanders , Stefan Walzer , Jonatan Ziegler

We describe properties and constructions of constraint-based codes for DNA-based data storage which account for the maximum repetition length and AT/GC balance. We present algorithms for computing the number of sequences with maximum…

Information Theory · Computer Science 2018-12-18 Kees A. Schouhamer Immink , Kui Cai

Motivated by the philosophy and phenomenal success of compressed sensing, the problem of reconstructing a matrix from a sampling of its entries has attracted much attention recently. Such a problem can be viewed as an information-theoretic…

Information Theory · Computer Science 2009-05-15 Zhisu Zhu , Anthony Man-Cho So , Yinyu Ye

Recently, DNA storage has surfaced as a promising alternative for data storage, presenting notable benefits in terms of storage capacity, cost-effectiveness in maintenance, and the capability for parallel replication. Mathematically, the…

Information Theory · Computer Science 2024-01-31 Yi Lu , Yun Ma , Chenghao Li , Xin Zhang , Guangxiang Si