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A promising approach to improve climate-model simulations is to replace traditional subgrid parameterizations based on simplified physical models by machine learning algorithms that are data-driven. However, neural networks (NNs) often lead…

Atmospheric and Oceanic Physics · Physics 2021-04-07 Janni Yuval , Paul A. O'Gorman , Chris N. Hill

The knowledge of the Free Energy Landscape topology is the essential key to understand many biochemical processes. The determination of the conformers of a protein and their basins of attraction takes a central role for studying molecular…

Biomolecules · Quantitative Biology 2009-06-26 Diego Prada-Gracia , Jesus Gomez-Gardenes , Pablo Echenique , Fernando Falo

We introduce the framework of continuous-depth graph neural networks (GNNs). Neural graph differential equations (Neural GDEs) are formalized as the counterpart to GNNs where the input-output relationship is determined by a continuum of GNN…

Machine Learning · Computer Science 2021-06-23 Michael Poli , Stefano Massaroli , Clayton M. Rabideau , Junyoung Park , Atsushi Yamashita , Hajime Asama , Jinkyoo Park

When studying high-dimensional dynamical systems such as macromolecules, quantum systems and polymers, a prime concern is the identification of the most probable states and their stationary probabilities or free energies. Often, these…

Data Analysis, Statistics and Probability · Physics 2013-01-01 Hao Wu , Frank Noé

Multivariate biosignals are prevalent in many medical domains, such as electroencephalography, polysomnography, and electrocardiography. Modeling spatiotemporal dependencies in multivariate biosignals is challenging due to (1) long-range…

Machine Learning · Computer Science 2023-05-02 Siyi Tang , Jared A. Dunnmon , Liangqiong Qu , Khaled K. Saab , Tina Baykaner , Christopher Lee-Messer , Daniel L. Rubin

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Bayesian brain theory suggests that the brain employs generative models to understand the external world. The sampling-based perspective posits that the brain infers the posterior distribution through samples of stochastic neuronal…

Artificial Intelligence · Computer Science 2023-10-24 Xingsi Dong , Si Wu

State-of-the-art Earth system models (ESMs) cannot explicitly resolve many small-scale atmospheric processes such as atmospheric gravity waves, and thus must represent, or parameterise, their effects on the resolved state. Machine learning…

Atmospheric and Oceanic Physics · Physics 2026-05-07 Elias Haslauer , Mierk Schwabe , Andreas Dörnbrack , Edwin P. Gerber , Markus Rapp , Nedjeljka Žagar , Veronika Eyring

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…

Neurons and Cognition · Quantitative Biology 2022-11-02 Yue Yu , Xuan Kan , Hejie Cui , Ran Xu , Yujia Zheng , Xiangchen Song , Yanqiao Zhu , Kun Zhang , Razieh Nabi , Ying Guo , Chao Zhang , Carl Yang

Wind power forecasting helps with the planning for the power systems by contributing to having a higher level of certainty in decision-making. Due to the randomness inherent to meteorological events (e.g., wind speeds), making highly…

Machine Learning · Computer Science 2023-01-04 Syed Kazmi , Berk Gorgulu , Mucahit Cevik , Mustafa Gokce Baydogan

Energy landscapes are a useful aid for the understanding of dynamical systems, and a valuable tool for their analysis. For a broad class of rate models of neural networks, we derive a global Lyapunov function which provides an energy…

Neurons and Cognition · Quantitative Biology 2018-08-24 R. R. Deza , J. I. Deza , N. Martinez , J. F. Mejias , H. S. Wio

Grid decarbonization for climate change requires dispatchable carbon-free energy like nuclear fusion. The tokamak concept offers a promising path for fusion, but one of the foremost challenges in implementation is the occurrence of…

Machine Learning · Computer Science 2023-12-05 William F Arnold , Lucas Spangher , Christina Rea

This paper presents a physics-informed neural network approach for dynamic modeling of saturable synchronous machines, including cases with spatial harmonics. We introduce an architecture that incorporates gradient networks directly into…

Systems and Control · Electrical Eng. & Systems 2026-02-17 Junyi Li , Tim Foissner , Floran Martin , Antti Piippo , Marko Hinkkanen

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Visual representations can be defined as the activations of neuronal populations in response to images. The activation of a neuron as a function over all image space has been described as a "tuning landscape". As a function over a…

Neurons and Cognition · Quantitative Biology 2022-12-29 Binxu Wang , Carlos R. Ponce

With electric power systems becoming more compact and increasingly powerful, the relevance of thermal stress especially during overload operation is expected to increase ceaselessly. Whenever critical temperatures cannot be measured…

Machine Learning · Computer Science 2022-11-03 Wilhelm Kirchgässner , Oliver Wallscheid , Joachim Böcker

Translating the complex, multi-dimensional data from simulations of biomolecules to intuitive knowledge is a major challenge in computational chemistry and biology. The so-called "free energy landscape" is amongst the most fundamental…

Human-Computer Interaction · Computer Science 2018-03-16 Robert E. Arbon , Alex J. Jones , Lars A. Bratholm , Tom Mitchell , David R. Glowacki

The human brain remains continuously active, whether an individual is working or at rest. Mental activity is a daily process, and if the brain becomes excessively active, known as overload, it can adversely affect human health. Recently,…

Signal Processing · Electrical Eng. & Systems 2024-03-13 Hong-Hai Nguyen , Ngumimi Karen Iyortsuun , Seungwon Kim , Hyung-Jeong Yang , Soo-Hyung Kim

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Machine learning techniques are being increasingly used as flexible non-linear fitting and prediction tools in the physical sciences. Fitting functions that exhibit multiple solutions as local minima can be analysed in terms of the…