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Retrieval-augmented generation combined with reinforcement learning has shown promise for grounding large language models in trustworthy medical evidence. However, existing methods rely on exact-match binary rewards, which in clinical…

Artificial Intelligence · Computer Science 2026-05-28 Yuwei Miao , Gen Li , Yunsheng Zeng , Xiandong Li , Yujin Wang , Siyu Chen , Luning Wang , Yunhao Qiao , Junfeng Wang , Jianwei Lv , Bo Yuan

Continual learning is essential for medical image classification systems to adapt to dynamically evolving clinical environments. The integration of multimodal information can significantly enhance continual learning of image classes.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Jiantao Tan , Peixian Ma , Kanghao Chen , Zhiming Dai , Ruixuan Wang

Large Language Models have been increasingly employed in the creation of Virtual Assistants due to their ability to generate human-like text and handle complex inquiries. While these models hold great promise, challenges such as…

Computation and Language · Computer Science 2026-04-30 Dumitru Verşebeniuc , Martijn Elands , Sara Falahatkar , Chiara Magrone , Mohammad Falah , Martijn Boussé , Aki Härmä

The importance of recommender systems is growing rapidly due to the exponential increase in the volume of content generated daily. This surge in content presents unique challenges for designing effective recommender systems. Key among these…

Computation and Language · Computer Science 2025-06-12 Jiahao Tian , Jinman Zhao , Zhenkai Wang , Zhicheng Ding

Large Language Models (LLMs) have shown great potential in the biomedical domain with the advancement of retrieval-augmented generation (RAG). However, existing retrieval-augmented approaches face challenges in addressing diverse queries…

Computation and Language · Computer Science 2024-10-17 Minda Hu , Licheng Zong , Hongru Wang , Jingyan Zhou , Jingjing Li , Yichen Gao , Kam-Fai Wong , Yu Li , Irwin King

Retrieval-Augmented Generation (RAG) struggles on long, structured financial filings where relevant evidence is sparse and cross-referenced. This paper presents a systematic investigation of advanced metadata-driven Retrieval-Augmented…

Information Retrieval · Computer Science 2025-10-29 Michail Dadopoulos , Anestis Ladas , Stratos Moschidis , Ioannis Negkakis

Large language models record impressive performance on many natural language processing tasks. However, their knowledge capacity is limited to the pretraining corpus. Retrieval augmentation offers an effective solution by retrieving context…

Computation and Language · Computer Science 2023-11-22 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana

Retrieval-Augmented Generation (RAG) has emerged as a powerful framework to improve factuality in large language models (LLMs) by grounding their outputs in retrieved documents. However, ensuring perfect retrieval of relevant information…

Computation and Language · Computer Science 2025-12-04 Zhan Peng Lee , Andre Lin , Calvin Tan

Retrieval Augmented Generation (RAG) systems have emerged as a powerful method for enhancing large language models (LLMs) with up-to-date information. However, the retrieval step in RAG can sometimes surface documents containing…

Computation and Language · Computer Science 2025-04-02 Vignesh Gokul , Srikanth Tenneti , Alwarappan Nakkiran

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Caregivers (i.e., parents and members of a child's caring community) are underappreciated stakeholders in learning analytics. Although caregiver involvement can enhance student academic outcomes, many obstacles hinder involvement, most…

Human-Computer Interaction · Computer Science 2024-12-17 Devika Venugopalan , Ziwen Yan , Conrad Borchers , Jionghao Lin , Vincent Aleven

Retrieval-Augmented Generation (RAG) systems enhance large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user needs. However, existing RAG systems…

Information Retrieval · Computer Science 2025-04-29 Zirui Guo , Lianghao Xia , Yanhua Yu , Tu Ao , Chao Huang

Multimodal foundation models hold significant potential for automating radiology report generation, thereby assisting clinicians in diagnosing cardiac diseases. However, generated reports often suffer from serious factual inaccuracy. In…

Computation and Language · Computer Science 2025-02-07 Liwen Sun , James Zhao , Megan Han , Chenyan Xiong

Older adults commonly experience chronic conditions such as pain and sleep disturbances and may consider cannabidiol for symptom management. Safe use requires appropriate dosing, careful titration, and awareness of drug interactions, yet…

Information Retrieval · Computer Science 2026-04-14 Ali Abedi , Charlene H. Chu , Shehroz S. Khan

Relevance judgments are crucial for evaluating information retrieval systems, but traditional human-annotated labels are time-consuming and expensive. As a result, many researchers turn to automatic alternatives to accelerate method…

Information Retrieval · Computer Science 2025-07-15 Naghmeh Farzi , Laura Dietz

Retrieval-Augmented Generation (RAG) systems for Large Language Models (LLMs) hold promise in knowledge-intensive tasks but face limitations in complex multi-step reasoning. While recent methods have integrated RAG with chain-of-thought…

Computation and Language · Computer Science 2025-01-15 Zhongxiang Sun , Qipeng Wang , Weijie Yu , Xiaoxue Zang , Kai Zheng , Jun Xu , Xiao Zhang , Song Yang , Han Li

Large language models (LLMs) typically enhance their performance through either the retrieval of semantically similar information or the improvement of their reasoning capabilities. However, a significant challenge remains in effectively…

Artificial Intelligence · Computer Science 2026-01-05 Shuqi Liu , Bowei He , Chen Ma , Linqi Song

Knowing that the generative capabilities of large language models (LLM) are sometimes hampered by tendencies to hallucinate or create non-factual responses, researchers have increasingly focused on methods to ground generated outputs in…

Information Retrieval · Computer Science 2024-11-20 Sonal Prabhune , Donald J. Berndt