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With the increasing availability of diverse data types, particularly images and time series data from medical experiments, there is a growing demand for techniques designed to combine various modalities of data effectively. Our motivation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Ali Rasekh , Reza Heidari , Amir Hosein Haji Mohammad Rezaie , Parsa Sharifi Sedeh , Zahra Ahmadi , Prasenjit Mitra , Wolfgang Nejdl

Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the…

Machine Learning · Computer Science 2017-07-18 Phuoc Nguyen , Truyen Tran , Svetha Venkatesh

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

Predicting the risk of mortality for patients with acute myocardial infarction (AMI) using electronic health records (EHRs) data can help identify risky patients who might need more tailored care. In our previous work, we built…

Machine Learning · Computer Science 2019-04-30 Seyedeh Neelufar Payrovnaziri , Laura A. Barrett , Daniel Bis , Jiang Bian , Zhe He

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

Machine Learning · Computer Science 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

With the improvement of medical data capturing, vast amount of continuous patient monitoring data, e.g., electrocardiogram (ECG), real-time vital signs and medications, become available for clinical decision support at intensive care units…

Machine Learning · Computer Science 2018-07-25 Yanbo Xu , Siddharth Biswal , Shriprasad R Deshpande , Kevin O Maher , Jimeng Sun

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

The recent success of machine learning methods applied to time series collected from Intensive Care Units (ICU) exposes the lack of standardized machine learning benchmarks for developing and comparing such methods. While raw datasets, such…

Machine Learning · Computer Science 2022-01-19 Hugo Yèche , Rita Kuznetsova , Marc Zimmermann , Matthias Hüser , Xinrui Lyu , Martin Faltys , Gunnar Rätsch

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Machine learning-aided clinical decision support has the potential to significantly improve patient care. However, existing efforts in this domain for principled quantification of uncertainty have largely been limited to applications of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 L. Julian Lechuga Lopez , Tim G. J. Rudner , Farah E. Shamout

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

Machine Learning · Computer Science 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

Artificial intelligence (AI) systems hold great promise to improve healthcare over the next decades. Specifically, AI systems leveraging multiple data sources and input modalities are poised to become a viable method to deliver more…

Elderly ICU patients with coexisting diabetes mellitus and heart failure experience markedly elevated short-term mortality, yet few predictive models are tailored to this high-risk group. Diabetes mellitus affects nearly 30% of U.S. adults…

Applications · Statistics 2025-06-19 Junyi Fan , Shuheng Chen , Li Sun , Yong Si , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The majority of biomedical studies use limited datasets that may not generalize over large heterogeneous datasets that have been collected over several decades. The current paper develops and validates several multimodal models that can…

Intensive care units (ICU) generate long, dense and evolving streams of clinical information, where physicians must repeatedly reassess patient states under time pressure, underscoring a clear need for reliable AI decision support. Existing…

Artificial Intelligence · Computer Science 2026-05-14 Chengzhi Shen , Weixiang Shen , Tobias Susetzky , Chen , Chen , Jun Li , Yuyuan Liu , Xuepeng Zhang , Zhenyu Gong , Daniel Rueckert , Jiazhen Pan

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few…

Machine Learning · Computer Science 2017-10-25 Sanjay Purushotham , Chuizheng Meng , Zhengping Che , Yan Liu

In-hospital mortality (IHM) prediction for ICU patients is critical for timely interventions and efficient resource allocation. While structured physiological data provides quantitative insights, clinical notes offer unstructured,…

Computation and Language · Computer Science 2024-11-27 Harshavardhan Battula , Jiacheng Liu , Jaideep Srivastava

Foundation models have emerged as a powerful approach for processing electronic health records (EHRs), offering flexibility to handle diverse medical data modalities. In this study, we present a comprehensive benchmark that evaluates the…

Machine Learning · Computer Science 2025-07-22 Kunyu Yu , Rui Yang , Jingchi Liao , Siqi Li , Huitao Li , Irene Li , Yifan Peng , Rishikesan Kamaleswaran , Nan Liu

Fever of unknown origin FUO remains a diagnostic challenge. MedMimic is introduced as a multimodal framework inspired by real-world diagnostic processes. It uses pretrained models such as DINOv2, Vision Transformer, and ResNet-18 to convert…

Image and Video Processing · Electrical Eng. & Systems 2025-02-17 Minrui Chen , Yi Zhou , Huidong Jiang , Yuhan Zhu , Guanjie Zou , Minqi Chen , Rong Tian , Hiroto Saigo