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Related papers: MedRAGChecker: Claim-Level Verification for Biomed…

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Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Retrieval-augmented generation (RAG) improves large language model reliability by grounding generated responses in external evidence. However, RAG performance depends on the relevance of retrieved passages, the quality of evidence ranking,…

Information Retrieval · Computer Science 2026-05-05 Fariba Afrin Irany , Sampson Akwafuo

Retrieval-augmented generation (RAG) is a well-suited technique for retrieving privacy-sensitive Electronic Health Records (EHR). It can serve as a key module of the healthcare copilot, helping reduce misdiagnosis for healthcare…

Computation and Language · Computer Science 2025-06-30 Xuejiao Zhao , Siyan Liu , Su-Yin Yang , Chunyan Miao

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Retrieval-Augmented Generation (RAG) significantly improves the factuality of Large Language Models (LLMs), yet standard pipelines often lack mechanisms to verify inter- mediate reasoning, leaving them vulnerable to hallucinations in…

Computation and Language · Computer Science 2026-03-12 Eeham Khan , Luis Rodriguez , Marc Queudot

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Despite the impressive capabilities of large language models (LLMs) across diverse applications, they still suffer from trustworthiness issues, such as hallucinations and misalignments. Retrieval-augmented language models (RAG) have been…

Artificial Intelligence · Computer Science 2024-07-31 Mintong Kang , Nezihe Merve Gürel , Ning Yu , Dawn Song , Bo Li

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Large language models (LLMs) inevitably exhibit hallucinations since the accuracy of generated texts cannot be secured solely by the parametric knowledge they encapsulate. Although retrieval-augmented generation (RAG) is a practicable…

Computation and Language · Computer Science 2024-10-08 Shi-Qi Yan , Jia-Chen Gu , Yun Zhu , Zhen-Hua Ling

Deploying Large Language Models (LLMs) for healthcare question answering requires robust methods to ensure accuracy and reliability. This work introduces Query-Based Retrieval Augmented Generation (QB-RAG), a framework for enhancing…

Machine Learning · Computer Science 2025-07-31 Eric Yang , Jonathan Amar , Jong Ha Lee , Bhawesh Kumar , Yugang Jia

Existing research on Retrieval-Augmented Generation (RAG) primarily focuses on improving overall question-answering accuracy, often overlooking the quality of sub-claims within generated responses. Recent methods that attempt to improve RAG…

Information Retrieval · Computer Science 2025-06-27 Naihe Feng , Yi Sui , Shiyi Hou , Jesse C. Cresswell , Ga Wu

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce…

Information Retrieval · Computer Science 2025-09-05 Shakiba Amirshahi , Amin Bigdeli , Charles L. A. Clarke , Amira Ghenai

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large Language Models (LLMs) augmented with retrieval mechanisms have demonstrated significant potential in fact-checking tasks by integrating external knowledge. However, their reliability decreases when confronted with conflicting…

Computation and Language · Computer Science 2025-05-26 Ziyu Ge , Yuhao Wu , Daniel Wai Kit Chin , Roy Ka-Wei Lee , Rui Cao

The indexing-retrieval-generation paradigm of retrieval-augmented generation (RAG) has been highly successful in solving knowledge-intensive tasks by integrating external knowledge into large language models (LLMs). However, the…

Cryptography and Security · Computer Science 2025-02-25 Xun Liang , Simin Niu , Zhiyu Li , Sensen Zhang , Hanyu Wang , Feiyu Xiong , Jason Zhaoxin Fan , Bo Tang , Shichao Song , Mengwei Wang , Jiawei Yang

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating external knowledge sources, enabling more accurate and contextually relevant responses tailored to user queries. These systems, however, remain…

Computation and Language · Computer Science 2025-05-26 Huichi Zhou , Kin-Hei Lee , Zhonghao Zhan , Yue Chen , Zhenhao Li , Zhaoyang Wang , Hamed Haddadi , Emine Yilmaz

Retrieval-Augmented Generation (RAG) enhances large language models (LLMs) by integrating their parametric knowledge with external retrieved content. However, knowledge conflicts caused by internal inconsistencies or noisy retrieved content…

Computation and Language · Computer Science 2025-07-03 Juan Chen , Baolong Bi , Wei Zhang , Jingyan Sui , Xiaofei Zhu , Yuanzhuo Wang , Lingrui Mei , Shenghua Liu

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Access to the right evidence does not guarantee that large language models (LLMs) will reason with it correctly. This gap between retrieval and reasoning is especially concerning in clinical settings, where outputs must align with…

Artificial Intelligence · Computer Science 2025-11-21 Deepthi Potluri , Aby Mammen Mathew , Jeffrey B DeWitt , Alexander L. Rasgon , Yide Hao , Junyuan Hong , Ying Ding