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Background: Investigational New Drug (IND) application preparation is time-intensive and expertise-dependent, slowing early clinical development. Objective: To evaluate whether a large language model (LLM) platform (AutoIND) can reduce…

Artificial Intelligence · Computer Science 2025-09-15 Umut Eser , Yael Gozin , L. Jay Stallons , Ari Caroline , Martin Preusse , Brandon Rice , Scott Wright , Andrew Robertson

Documentation burden is a major contributor to clinician burnout, which is rising nationally and is an urgent threat to our ability to care for patients. Artificial intelligence (AI) chatbots, such as ChatGPT, could reduce clinician burden…

The advent of Generative Artificial Intelligence (GAI) has revolutionized the field of writing, marking a shift towards human-AI collaborative writing in education. However, the dynamics of human-AI interaction in the collaborative writing…

Human-Computer Interaction · Computer Science 2024-06-24 Kaixun Yang , Yixin Cheng , Linxuan Zhao , Mladen Raković , Zachari Swiecki , Dragan Gašević , Guanliang Chen

Generative Artificial Intelligence (AI) holds immense potential in medical applications. Numerous studies have explored the efficacy of various generative AI models within healthcare contexts, but there is a lack of a comprehensive and…

Human-Computer Interaction · Computer Science 2023-12-19 Jinghong Chen , Lingxuan Zhu , Weiming Mou , Zaoqu Liu , Quan Cheng , Anqi Lin , Jian Zhang , Peng Luo

Code review is a critical software engineering practice where developers review code changes before integration to ensure code quality, detect defects, and improve maintainability. In recent years, AI agents that can understand code…

Software Engineering · Computer Science 2026-03-18 Suzhen Zhong , Shayan Noei , Ying Zou , Bram Adams

To explore how humans can best leverage LLMs for writing and how interacting with these models affects feelings of ownership and trust in the writing process, we compared common human-AI interaction types (e.g., guiding system, selecting…

Computation and Language · Computer Science 2023-10-19 Zijian Ding , Alison Smith-Renner , Wenjuan Zhang , Joel R. Tetreault , Alejandro Jaimes

Artificial intelligence (AI) has demonstrated strong potential in clinical diagnostics, often achieving accuracy comparable to or exceeding that of human experts. A key challenge, however, is that AI reasoning frequently diverges from…

Artificial Intelligence · Computer Science 2026-05-25 Belona Sonna , Alban Grastien

Generative AI (GenAI) systems are inherently non-deterministic, producing varied outputs even for identical inputs. While this variability is central to their appeal, it challenges established HCI evaluation practices that typically assume…

Human-Computer Interaction · Computer Science 2026-01-30 Hyerim Park , Khanh Huynh , Malin Eiband , Jeremy Dillmann , Sven Mayer , Michael Sedlmair

Medical conversations between patients and medical professionals have implicit functional sections, such as "history taking", "summarization", "education", and "care plan." In this work, we are interested in learning to automatically…

Computation and Language · Computer Science 2022-10-10 Mengqian Wang , Ilya Valmianski , Xavier Amatriain , Anitha Kannan

Trust in clinical artificial intelligence (AI) cannot be reduced to model accuracy, fluency of generation, or overall positive user impression. In medicine, trust must be engineered as a measurable system property grounded in evidence,…

Computation and Language · Computer Science 2026-04-30 Serhii Zabolotnii , Viktoriia Holinko , Olha Antonenko

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…

Computation and Language · Computer Science 2018-08-09 Peter J. Liu

AI-enabled decision-support systems aim to help medical providers rapidly make decisions with limited information during medical emergencies. A critical challenge in developing these systems is supporting providers in interpreting the…

The increasing prevalence of retinal diseases poses a significant challenge to the healthcare system, as the demand for ophthalmologists surpasses the available workforce. This imbalance creates a bottleneck in diagnosis and treatment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-17 Jia-Hong Huang

Accurate representation of medical information is crucial for patient safety, yet artificial intelligence (AI) systems, such as Large Language Models (LLMs), encounter challenges in error-free clinical text interpretation. This paper…

Computation and Language · Computer Science 2024-04-30 Nadia Saeed

Conventional picture-book production imposes substantial physical and temporal demands on creators, often constraining opportunities for high-level artistic exploration. While generative AI can drastically accelerate image generation,…

Human-Computer Interaction · Computer Science 2026-04-07 Cosei Kawa

As AI systems become increasingly capable and autonomous, domain experts' roles are shifting from performing tasks themselves to overseeing AI-generated outputs. Such oversight is critical, as undetected errors can have serious consequences…

Human-Computer Interaction · Computer Science 2026-03-05 Cedric Faas , Sophie Kerstan , Richard Uth , Markus Langer , Anna Maria Feit

Agentic Artificial Intelligence (AI) systems, exemplified by OpenAI's DeepResearch, autonomously pursue goals, adapting strategies through implicit learning. Unlike traditional generative AI, which is reactive to user prompts, agentic AI…

Computers and Society · Computer Science 2025-04-08 Anirban Mukherjee , Hannah Hanwen Chang

This study explores the challenge of sentence-level AI-generated text detection within human-AI collaborative hybrid texts. Existing studies of AI-generated text detection for hybrid texts often rely on synthetic datasets. These typically…

Computation and Language · Computer Science 2024-05-24 Zijie Zeng , Shiqi Liu , Lele Sha , Zhuang Li , Kaixun Yang , Sannyuya Liu , Dragan Gašević , Guanliang Chen

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying,…

Computation and Language · Computer Science 2024-10-30 Zifeng Wang , Lang Cao , Benjamin Danek , Qiao Jin , Zhiyong Lu , Jimeng Sun

Design optimizations in human-AI collaboration often focus on cognitive aspects like attention and task load. Drawing on work design literature, we propose that effective human-AI collaboration requires broader consideration of human needs…

Human-Computer Interaction · Computer Science 2024-10-11 Cedric Faas , Richard Bergs , Sarah Sterz , Markus Langer , Anna Maria Feit
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