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Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

Physics-informed neural networks (PINNs) have shown remarkable prospects in solving partial differential equations (PDEs) involving fluid mechanics. However, the method has so far succeeded only in inviscid flows and incompressible viscous…

Fluid Dynamics · Physics 2026-02-24 Jiahao Song , Wenbo Cao , Weiwei Zhang

Physics-informed neural networks (PINNs) provide a mesh-free framework for solving partial differential equations by embedding governing physics into neural-network training. Recent studies have shown that parameterized PINNs can learn…

Fluid Dynamics · Physics 2026-05-29 A. Jangir , R. Clements , R. Goyal , G. Tabor

We employ physics-informed neural networks (PINNs) to simulate the incompressible flows ranging from laminar to turbulent flows. We perform PINN simulations by considering two different formulations of the Navier-Stokes equations: the…

Computational Physics · Physics 2021-02-03 Xiaowei Jin , Shengze Cai , Hui Li , George Em Karniadakis

Physics-informed neural networks (PINNs) represent a new paradigm for solving partial differential equations (PDEs) by integrating physical laws into the learning process of neural networks. However, ensuring that such frameworks fully…

Machine Learning · Computer Science 2025-12-12 Nanxi Chen , Sifan Wang , Rujin Ma , Airong Chen , Chuanjie Cui

Physics-Informed Neural Network (PINN) is a novel multi-task learning framework useful for solving physical problems modeled using differential equations (DEs) by integrating the knowledge of physics and known constraints into the…

Machine Learning · Computer Science 2024-09-18 Shivprasad Kathane , Shyamprasad Karagadde

This paper develops a novel deep learning approach for solving evolutionary equations, which integrates sequential learning strategies with an enhanced hard constraint strategy featuring trainable parameters, addressing the low…

Machine Learning · Computer Science 2025-03-25 Yushi Zhang , Shuai Su , Yong Wang , Yanzhong Yao

The accurate solution of nonlinear hyperbolic partial differential equations (PDEs) remains challenging due to steep gradients, discontinuities, and multiscale structures that make conventional solvers computationally demanding.…

Machine Learning · Computer Science 2025-12-02 Saif Ur Rehman , Wajid Yousuf

Physics-Informed Neural Networks (PINNs) show significant potential for solving inverse problems, especially when observations are limited and sparse, provided that the relevant physical equations are known. We use PINNs to estimate smooth…

Numerical Analysis · Mathematics 2025-08-06 Moises Sierpe , Ernesto Castillo , Hernan Mella , Felipe Galarce

The transformative impact of machine learning, particularly Deep Learning (DL), on scientific and engineering domains is evident. In the context of computational fluid dynamics (CFD), Physics-Informed Neural Networks (PINNs) represent a…

Fluid Dynamics · Physics 2024-04-05 Siddharth Raghu , Rajdip Nayek , Vamsi Chalamalla

Physics-informed neural networks (PINNs), owing to their mesh-free nature, offer a powerful approach for solving high-dimensional partial differential equations (PDEs) in complex geometries, including irregular domains. This capability…

Numerical Analysis · Mathematics 2025-06-06 Hanfei Zhou , Lei Shi

The utilization of Deep Neural Networks (DNNs) in physical science and engineering applications has gained traction due to their capacity to learn intricate functions. While large datasets are crucial for training DNN models in fields like…

Machine Learning · Computer Science 2025-08-05 Vamsi Sai Krishna Malineni , Suresh Rajendran

We develop a new class of physics-informed neural network approximations for the stationary Oseen equations based on stability-consistent loss constructions. In contrast to standard PINN formulations, which are typically heuristic, the…

Numerical Analysis · Mathematics 2026-05-07 Shiv Mishra , Arbaz Khan

Physics Informed Neural Networks (PINNs) are shown to be a promising method for the approximation of Partial Differential Equations (PDEs). PINNs approximate the PDE solution by minimizing physics-based loss functions over a given domain.…

Numerical Analysis · Mathematics 2022-09-13 Shoaib Goraya , Nahil Sobh , Arif Masud

We leverage Physics-Informed Neural Networks (PINNs) to learn solution functions of parametric Navier-Stokes Equations (NSE). Our proposed approach results in a feasible optimization problem setup that bypasses PINNs' limitations in…

Computational Engineering, Finance, and Science · Computer Science 2024-02-06 M. Naderibeni , M. J. T. Reinders , L. Wu , D. M. J. Tax

Physics-informed neural networks (PINNs) are able to solve partial differential equations (PDEs) by incorporating the residuals of the PDEs into their loss functions. Variational Physics-Informed Neural Networks (VPINNs) and hp-VPINNs use…

This paper presents a framework for physics-informed learning in complex cyber-physical systems governed by differential equations with both unknown dynamics and algebraic invariants. First, we formalize the Hybrid Recurrent…

Machine Learning · Computer Science 2025-12-01 Enzo Nicolás Spotorno , Josafat Leal Filho , Antônio Augusto Fröhlich

Physics-informed neural networks (PINNs) provide a framework to build surrogate models for dynamical systems governed by differential equations. During the learning process, PINNs incorporate a physics-based regularization term within the…

Machine Learning · Computer Science 2023-08-14 Shinjan Ghosh , Amit Chakraborty , Georgia Olympia Brikis , Biswadip Dey

We propose a novel projection method that guarantees the conservation of integral quantities in Physics-Informed Neural Networks (PINNs). While the soft constraint that PINNs use to enforce the structure of partial differential equations…

Machine Learning · Computer Science 2026-05-26 Anthony Baez , Wang Zhang , Ziwen Ma , Lam Nguyen , Subhro Das , Luca Daniel

This paper introduces a framework based on physics-informed neural networks (PINNs) for addressing key challenges in nonlinear lattices, including solution approximation, bifurcation diagram construction, and linear stability analysis. We…

Numerical Analysis · Mathematics 2025-07-22 Muhammad Luthfi Shahab , Fidya Almira Suheri , Rudy Kusdiantara , Hadi Susanto