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Medical image segmentation plays a crucial role in clinical medicine, serving as a key tool for auxiliary diagnosis, treatment planning, and disease monitoring. However, traditional segmentation methods such as U-Net are often limited by…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Gaoyu Chen , Haixia Pan

Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Abdul Qayyum , Moona Mazher Imran Razzak , Steven A Niederer

Transformer architecture has emerged to be successful in a number of natural language processing tasks. However, its applications to medical vision remain largely unexplored. In this study, we present UTNet, a simple yet powerful hybrid…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Yunhe Gao , Mu Zhou , Dimitris Metaxas

A U-Net based deep learning architecture is designed to segment brain tumors as they appear on various MRI modalities. Special emphasis is lent to the non-enhancing tumor compartment. The latter has not been considered anymore in recent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 T. Schaffer , A. Brawanski , S. Wein , A. M. Tomé , E. W. Lang

Brain Tumor Segmentation from magnetic resonance imaging (MRI) is a critical technique for early diagnosis. However, rather than having complete four modalities as in BraTS dataset, it is common to have missing modalities in clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Yan Shen , Mingchen Gao

Deep learning-based techniques have been widely utilized for brain tumor segmentation using both single and multi-modal Magnetic Resonance Imaging (MRI) images. Most current studies focus on centralized training due to the intrinsic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Ruojun Zhou , Lisha Qu , Lei Zhang , Ziming Li , Hongwei Yu , Bing Luo

Brain metastasis segmentation poses a significant challenge in medical imaging due to the complex presentation and variability in size and location of metastases. In this study, we first investigate the impact of different imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-07-22 Yousef Sadegheih , Dorit Merhof

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin

Cancer subtype classification is crucial for personalized treatment and prognostic assessment. However, effectively integrating multi-omic data remains challenging due to the heterogeneous nature of genomic, epigenomic, and transcriptomic…

Machine Learning · Computer Science 2025-06-10 Sajib Acharjee Dip , Uddip Acharjee Shuvo , Dipanwita Mallick , Abrar Rahman Abir , Liqing Zhang

The high cure rate of cancer is inextricably linked to physicians' accuracy in diagnosis and treatment, therefore a model that can accomplish high-precision tumor segmentation has become a necessity in many applications of the medical…

Image and Video Processing · Electrical Eng. & Systems 2023-07-26 Zeqiu. Yu , Shuo. Han , Ziheng. Song

Brain tumors, particularly glioblastoma, continue to challenge medical diagnostics and treatments globally. This paper explores the application of deep learning to multi-modality magnetic resonance imaging (MRI) data for enhanced brain…

Image and Video Processing · Electrical Eng. & Systems 2023-08-15 Chiranjeewee Prasad Koirala , Sovesh Mohapatra , Advait Gosai , Gottfried Schlaug

A major challenge in brain tumor treatment planning and quantitative evaluation is determination of the tumor extent. The noninvasive magnetic resonance imaging (MRI) technique has emerged as a front-line diagnostic tool for brain tumors…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Hao Dong , Guang Yang , Fangde Liu , Yuanhan Mo , Yike Guo

Accurate segmentation of brain tumour sub-regions from multi-parametric MRI is critical for treatment planning yet remains challenging due to morphological variability, class imbalance, and overlapping appearances of tumour regions across…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Hasaan Maqsood , Saif Ur Rehman Khan , Sebastian Vollmer , Andreas Dengel , Muhammad Nabeel Asim

Recent rising interests in patient-specific thoracic surgical planning and simulation require efficient and robust creation of digital anatomical models from automatic medical image segmentation algorithms. Deep learning (DL) is now…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Arash Harirpoush , Amirhossein Rasoulian , Marta Kersten-Oertel , Yiming Xiao

Prostate cancer biopsy benefits from accurate fusion of transrectal ultrasound (TRUS) and magnetic resonance (MR) images. In the past few years, convolutional neural networks (CNNs) have been proved powerful in extracting image features…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Xinrui Song , Hengtao Guo , Xuanang Xu , Hanqing Chao , Sheng Xu , Baris Turkbey , Bradford J. Wood , Ge Wang , Pingkun Yan

We share our recent findings in an attempt to train a universal segmentation network for various cell types and imaging modalities. Our method was built on the generalized U-Net architecture, which allows the evaluation of each component…

Computer Vision and Pattern Recognition · Computer Science 2022-08-01 Tianqi Guo , Yin Wang , Luis Solorio , Jan P. Allebach

Accurate segmentation of brain tumors from magnetic resonance imaging (MRI) is clinically relevant in diagnoses, prognoses and surgery treatment, which requires multiple modalities to provide complementary morphological and physiopathologic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-30 Yixin Wang , Yang Zhang , Yang Liu , Zihao Lin , Jiang Tian , Cheng Zhong , Zhongchao Shi , Jianping Fan , Zhiqiang He

Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Glioma is a harmful brain tumor that requires early detection to ensure better health results. Early detection of this tumor is key for effective treatment and requires an automated segmentation process. However, it is a challenging task to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Mohsen Yaghoubi Suraki

We apply nnU-Net to the segmentation task of the BraTS 2020 challenge. The unmodified nnU-Net baseline configuration already achieves a respectable result. By incorporating BraTS-specific modifications regarding postprocessing, region-based…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 Fabian Isensee , Paul F. Jaeger , Peter M. Full , Philipp Vollmuth , Klaus H. Maier-Hein