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Unsupervised pre-training is now the predominant approach for both text and speech understanding. Self-attention models pre-trained on large amounts of unannotated data have been hugely successful when fine-tuned on downstream tasks from a…

Real-world live retrieval-augmented generation (RAG) systems face significant challenges when processing user queries that are often noisy, ambiguous, and contain multiple intents. While RAG enhances large language models (LLMs) with…

Automated single-cell annotation is difficult when the most abundant genes are not the most discriminative ones, or when a target state is poorly covered by a fixed reference atlas. GPTCelltype-style one-shot prompting allows large language…

Knowledge enhanced pre-trained language models (K-PLMs) are shown to be effective for many public tasks in the literature but few of them have been successfully applied in practice. To address this problem, we propose K-AID, a systematic…

This paper presents an ontology-aware pretrained language model (OPAL) for end-to-end task-oriented dialogue (TOD). Unlike chit-chat dialogue models, task-oriented dialogue models fulfill at least two task-specific modules: dialogue state…

We present Clinical Camel, an open large language model (LLM) explicitly tailored for clinical research. Fine-tuned from LLaMA-2 using QLoRA, Clinical Camel achieves state-of-the-art performance across medical benchmarks among openly…

Retrieval-augmented Generation (RAG) enhances Large Language Models (LLMs) by integrating external knowledge to reduce hallucinations and incorporate up-to-date information without retraining. As an essential part of RAG, external knowledge…

Reinforcement Learning (RL) has shown promise in improving the reasoning abilities of Large Language Models (LLMs). However, the specific challenges of adapting RL to multimodal data and formats remain relatively unexplored. In this work,…

Large language models have emerged as a promising approach towards achieving general-purpose AI agents. The thriving open-source LLM community has greatly accelerated the development of agents that support human-machine dialogue interaction…

Many real-world applications involve the use of Optical Character Recognition (OCR) engines to transform handwritten images into transcripts on which downstream Natural Language Processing (NLP) models are applied. In this process, OCR…

Multilingual automatic speech recognition (ASR) models have shown great promise in recent years because of the simplified model training and deployment process. Conventional methods either train a universal multilingual model without taking…

The field of natural language processing (NLP) has recently seen a large change towards using pre-trained language models for solving almost any task. Despite showing great improvements in benchmark datasets for various tasks, these models…

Foundation models have revolutionized natural language processing and artificial intelligence, significantly enhancing how machines comprehend and generate human languages. Inspired by the success of these foundation models, researchers…

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

The unprecedented performance of large language models (LLMs) necessitates improvements in evaluations. Rather than merely exploring the breadth of LLM abilities, we believe meticulous and thoughtful designs are essential to thorough,…

Offline reinforcement learning (RL) aims to find a near-optimal policy using pre-collected datasets. In real-world scenarios, data collection could be costly and risky; therefore, offline RL becomes particularly challenging when the…

Recent studies have demonstrated the feasibility of modeling single-cell data as natural languages and the potential of leveraging powerful large language models (LLMs) for understanding cell biology. However, a comprehensive evaluation of…

Previous language model pre-training methods have uniformly applied a next-token prediction loss to all training tokens. Challenging this norm, we posit that "9l training". Our initial analysis examines token-level training dynamics of…

Large Language Model (LLM) unlearning aims to erase or suppress undesirable knowledge within the model, offering promise for controlling harmful or private information to prevent misuse. However, recent studies highlight its limited…

Modeling the dynamics of cellular differentiation is fundamental to advancing the understanding and treatment of diseases associated with this process, such as cancer. With the rapid growth of single-cell datasets, this has also become a…