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We propose a novel optimization model for volumetric modulated arc therapy (VMAT) planning that directly optimizes deliverable leaf trajectories in the treatment plan optimization problem, and eliminates the need for a separate…

Medical Physics · Physics 2014-03-05 Dávid Papp , Jan Unkelbach

Medical imaging plays a crucial role in modern healthcare by providing non-invasive visualisation of internal structures and abnormalities, enabling early disease detection, accurate diagnosis, and treatment planning. This study aims to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-25 Walid Ehab , Yongmin Li

Background: Conventional prediction methods such as logistic regression and gradient boosting have been widely utilized for disease onset prediction for their reliability and interpretability. Deep learning methods promise enhanced…

Despite the success of machine learning (ML) in surrogate modeling, its use in radiation dose assessment is limited by safety-critical constraints, scarce training-ready data, and challenges in selecting suitable architectures for…

Machine Learning · Computer Science 2026-02-24 Biswajit Sadhu , Kalpak Gupte , Trijit Sadhu , S. Anand

Cancer is a primary cause of morbidity and mortality worldwide. The radiotherapy plays a more and more important role in cancer treatment. In the radiotherapy, the dose distribution maps in patient need to be calculated and evaluated for…

Medical Physics · Physics 2019-10-18 Zhao Peng , Hongming Shan , Tianyu Liu , Xi Pei , Jieping Zhou , Ge Wang , X. George Xu

A novel approach combining agile beam switching with deep learning to enhance the speed and accuracy of Direction of Arrival (DOA) estimation for millimeter-wave (mmWave) phased array systems with low-complexity hardware implementations is…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Arav Sharma , Lei Chi , Ari Gebhardt , Alon S. Levin , Timothy R. Hoerning , Sam Keene

Depth estimation (DE) provides spatial information about a scene and enables tasks such as 3D reconstruction, object detection, and scene understanding. Recently, there has been an increasing interest in using deep learning (DL)-based…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Ali Rohan , Md Junayed Hasan , Andrei Petrovski

Deep Learning (DL) holds enormous potential for improving medical imaging diagnostics, yet the lack of interpretability in most models hampers clinical trust and adoption. This paper presents an explainable deep learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Sai Teja Erukude , Viswa Chaitanya Marella , Suhasnadh Reddy Veluru

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

Active learning is a unique abstraction of machine learning techniques where the model/algorithm could guide users for annotation of a set of data points that would be beneficial to the model, unlike passive machine learning. The primary…

Computer Vision and Pattern Recognition · Computer Science 2021-01-08 Vishwesh Nath , Dong Yang , Bennett A. Landman , Daguang Xu , Holger R. Roth

Objective: To assess the performance of a probabilistic deep learning based algorithm for predicting inter-fraction anatomical changes in head and neck patients. Approach: A probabilistic daily anatomy model for head and neck patients…

Medical Physics · Physics 2024-11-12 Tiberiu Burlacu , Mischa Hoogeman , Danny Lathouwers , Zoltán Perkó

Purpose: This study presents a Deep Learning (DL)-based quality assessment (QA) approach for evaluating auto-generated contours (auto-contours) in radiotherapy, with emphasis on Online Adaptive Radiotherapy (OART). Leveraging Bayesian…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Biling Wang , Austen Maniscalco , Ti Bai , Siqiu Wang , Michael Dohopolski , Mu-Han Lin , Chenyang Shen , Dan Nguyen , Junzhou Huang , Steve Jiang , Xinlei Wang

In this work we explored the use of patient specific reinforced learning to generate 3D activity maps from two 2D planar images (anterior and posterior). The solution of this problem remains unachievable using conventional methodologies and…

Accurate segmentation is crucial for clinical applications, but existing models often assume fixed, high-resolution inputs and degrade significantly when faced with lower-resolution data in real-world scenarios. To address this limitation,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Simon Winther Albertsen , Hjalte Svaneborg Bjørnstrup , Mostafa Mehdipour Ghazi

Adaptive radiotherapy (ART), especially online ART, effectively accounts for positioning errors and anatomical changes. One key component of online ART is accurately and efficiently delineating organs at risk (OARs) and targets on online…

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep learning algorithm that can accurately detect breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen , Laurie R. Margolies , Joseph H. Rothstein , Eugene Fluder , Russell B. McBride , Weiva Sieh

Depth prediction is a critical problem in robotics applications especially autonomous driving. Generally, depth prediction based on binocular stereo matching and fusion of monocular image and laser point cloud are two mainstream methods.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Guancheng Chen , Junli Lin , Huabiao Qin

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

Personalized computed tomography (CT) dosimetry has great potential in assessing patient-specific radiation exposure, supporting risk assessment, and optimizing clinical protocols. The aim of this study is to evaluate the potential of…

Medical Physics · Physics 2026-01-15 Marie-Luise Kuhlmann , Jörg Martin , Stefan Pojtinger

This paper presents a deep learning framework for image classification aimed at increasing predictive performance for Cytotoxic Edema (CE) diagnosis in infants and children. The proposed framework includes two 3D network architectures…

Image and Video Processing · Electrical Eng. & Systems 2022-10-11 Henok Ghebrechristos , Stence Nicholas , David Mirsky , Gita Alaghband , Manh Huynh , Zackary Kromer , Ligia Batista , Brent ONeill , Steven Moulton , Daniel M. Lindberg