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Background: Parkinson's disease (PD) is a prevalent long-term neurodegenerative disease. Though the diagnostic criteria of PD are relatively well defined, the current medical imaging diagnostic procedures are expertise-demanding, and thus…

Quantitative Methods · Quantitative Biology 2019-02-27 Jiahang Xu , Fangyang Jiao , Yechong Huang , Xinzhe Luo , Qian Xu , Ling Li , Xueling Liu , Chuantao Zuo , Ping Wu , Xiahai Zhuang

Deep learning has shown significant potential in diagnosing neurodegenerative diseases from MRI data. However, most existing methods rely heavily on large volumes of labeled data and often yield representations that lack interpretability.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Fangqi Cheng , Yingying Zhao , Xiaochen Yang

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

Machine Learning · Computer Science 2020-10-14 Jie Mei , Christian Desrosiers , Johannes Frasnelli

Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of…

We evaluate the effectiveness of combining brain connectivity metrics with signal statistics for early stage Parkinson's Disease (PD) classification using electroencephalogram data (EEG). The data is from 5 arousal states - wakeful and four…

Neurons and Cognition · Quantitative Biology 2024-08-02 Amarpal Sahota , Amber Roguski , Matthew W Jones , Zahraa S. Abdallah , Raul Santos-Rodriguez

Although recent studies have proposed seizure detection algorithms with good sensitivity performance, there is a remained challenge that they were hard to achieve significantly short detection latency in real-time scenarios. In this…

Signal Processing · Electrical Eng. & Systems 2023-06-29 Yankun Xu , Jie Yang , Wenjie Ming , Shuang Wang , Mohamad Sawan

Parkinson's disease (PD) is a neurological disorder requiring early and accurate diagnosis for effective management. Machine learning (ML) has emerged as a powerful tool to enhance PD classification and diagnostic accuracy, particularly by…

Interpretation of electrocardiography (ECG) signals is required for diagnosing cardiac arrhythmia. Recently, machine learning techniques have been applied for automated computer-aided diagnosis. Machine learning tasks can be divided into…

Objective. Supervised learning paradigms are often limited by the amount of labeled data that is available. This phenomenon is particularly problematic in clinically-relevant data, such as electroencephalography (EEG), where labeling can be…

Machine Learning · Statistics 2020-08-03 Hubert Banville , Omar Chehab , Aapo Hyvärinen , Denis-Alexander Engemann , Alexandre Gramfort

Electrocardiography is a very common, non-invasive diagnostic procedure and its interpretation is increasingly supported by automatic interpretation algorithms. The progress in the field of automatic ECG interpretation has up to now been…

Machine Learning · Computer Science 2020-04-29 Nils Strodthoff , Patrick Wagner , Tobias Schaeffter , Wojciech Samek

At present, the majority of the proposed Deep Learning (DL) methods provide point predictions without quantifying the models uncertainty. However, a quantification of the reliability of automated image analysis is essential, in particular…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Lisa Herzog , Elvis Murina , Oliver Dürr , Susanne Wegener , Beate Sick

An important paradigm in smart health is developing diagnosis tools and monitoring a patient's heart activity through processing Electrocardiogram (ECG) signals is a key example, sue to high mortality rate of heart-related disease. However,…

Signal Processing · Electrical Eng. & Systems 2018-11-02 Jiaming Chen , Ali Valehi , Abolfazl Razi

Clinical methods that assess gait in Parkinson's Disease (PD) are mostly qualitative. Quantitative methods necessitate costly instrumentation or cumbersome wearable devices, which limits their usability. Only few of these methods can…

Machine Learning · Computer Science 2020-06-23 Nabeel Seedat , Vered Aharonson

Cross-validation plays a fundamental role in Machine Learning, enabling robust evaluation of model performance and preventing overestimation on training and validation data. However, one of its drawbacks is the potential to create data…

Machine Learning · Computer Science 2025-08-28 Afonso Martini Spezia , Thomas Fontanari , Mariana Recamonde-Mendoza

Brain vessel segmentation of MR scans is a critical step in the diagnosis of cerebrovascular diseases. Due to the fine vessel structure, manual vessel segmentation is time consuming. Therefore, automatic deep learning (DL) based…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Omini Rathore , Richard Paul , Abigail Morrison , Hanno Scharr , Elisabeth Pfaehler

This paper studies the classification problem on electroencephalogram (EEG) data of mental tasks, using standard architecture of three-layer CNN, stacked LSTM, stacked GRU. We further propose a novel classifier - a mixed LSTM model with a…

Signal Processing · Electrical Eng. & Systems 2019-10-09 Zeyu Bai , Ruizhi Yang , Youzhi Liang

Machine learning (ML) has the potential to become an essential tool in supporting clinical decision-making processes, offering enhanced diagnostic capabilities and personalized treatment plans. However, outsourcing medical records to train…

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

Numerical Analysis · Mathematics 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

In recent years, deep learning has shown potential and efficiency in a wide area including computer vision, image and signal processing. Yet, translational challenges remain for user applications due to a lack of interpretability of…

Machine Learning · Computer Science 2022-07-12 Hamid Niknazar , Sara C. Mednick

Decoding the human brain from electroencephalography (EEG) signals holds promise for understanding neurological activities. However, EEG data exhibit heterogeneity across subjects and sessions, limiting the generalization of existing…

Computational Engineering, Finance, and Science · Computer Science 2026-02-03 Zhi Zhang , Yan Liu , Zhejing Hu , Gong Chen , Jiannong Cao , Shenghua Zhong , Sean Fontaine , Changhong Jing , Shuqiang Wang
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