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Acceleration of machine learning research in healthcare is challenged by lack of large annotated and balanced datasets. Furthermore, dealing with measurement inaccuracies and exploiting unsupervised data are considered to be central to…
Parkinsons disease (PD) diagnosis is challenging due to subtle early clinical signs. F-DOPA PET is commonly used for early PD diagnosis. We explore the potential of machine-learning (ML) based EEG features extracted from single-channel EEG…
Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…
Automated electrocardiogram (ECG) classification is essential for early detection of cardiovascular diseases. While recent approaches have increasingly relied on deep neural networks with complex architectures, we demonstrate that careful…
Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…
We introduce a unified benchmarking framework focused on evaluating EEG-based foundation models in clinical applications. The benchmark spans 11 well-defined diagnostic tasks across 14 publicly available EEG datasets, including epilepsy,…
Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…
Pathological slowing in the electroencephalogram (EEG) is widely investigated for the diagnosis of neurological disorders. Currently, the gold standard for slowing detection is the visual inspection of the EEG by experts, which is…
Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…
Early-stage Parkinson's disease (EarlyPD) detection from speech is clinically meaningful yet underexplored, and published results are hard to compare because studies differ in datasets, languages, tasks, evaluation protocols, and EarlyPD…
Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…
Parkinson's Disease (PD) affects millions globally, impacting movement. Prior research utilized deep learning for PD prediction, primarily focusing on medical images, neglecting the data's underlying manifold structure. This work proposes a…
Electroencephalography signals (EEGs) contain rich multi-scale information crucial for understanding brain states, with potential applications in diagnosing and advancing the drug development landscape. However, extracting meaningful…
Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…
Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…
Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…
In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…
Recent works in pathological speech analysis have increasingly relied on powerful self-supervised speech representations, leading to promising results. However, the complex, black-box nature of these embeddings and the limited research on…
Early and accurate detection of Parkinson's disease (PD) is a crucial diagnostic challenge carrying immense clinical significance, for effective treatment regimens and patient management. For instance, a group of subjects termed SWEDD who…
Parkinson's disease (PD), a degenerative disorder of the central nervous system, is commonly diagnosed using functional medical imaging techniques such as single-photon emission computed tomography (SPECT). In this study, we utilized two…