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Irregularly sampled time series data are common in a variety of fields. Many typical methods for drawing insight from data fail in this case. Here we attempt to generalize methods for clustering trajectories to irregularly and sparsely…

Quantitative Methods · Quantitative Biology 2021-09-01 Gary K. Nave , Swati Padhee , Amanuel Alambo , Tanvi Banerjee , Nirmish Shah , Daniel M. Abrams

Nearly a quarter of visits to the Emergency Department are for conditions that could have been managed via outpatient treatment; improvements that allow patients to quickly recognize and receive appropriate treatment are crucial. The…

Quantitative Methods · Quantitative Biology 2021-12-01 Sara M. Clifton , Chaeryon Kang , Jingyi Jessica Li , Qi Long , Nirmish Shah , Daniel M. Abrams

The integration of machine learning and deep learning has transformed data analytics in biomechanics, enabled by extensive wearable sensor data. However, the field faces challenges such as limited large-scale datasets and high data…

Machine Learning · Computer Science 2025-08-26 Christina Halmich , Lucas Höschler , Christoph Schranz , Christian Borgelt

This article develops a novel data assimilation methodology, addressing challenges that are common in real-world settings, such as severe sparsity of observations, lack of reliable models, and non-stationarity of the system dynamics. These…

Optimization and Control · Mathematics 2024-11-05 David J. Abers , George Hripcsak , Lena Mamykina , Melike Sirlanci , Esteban G. Tabak

The use of observational time series data to assess the impact of multi-time point interventions is becoming increasingly common as more health and activity data are collected and digitized via wearables, social media, and electronic health…

Methodology · Statistics 2020-12-01 Roy Adams , Suchi Saria , Michael Rosenblum

Novel methods for rapidly estimating single-photon source (SPS) quality have been promoted in recent literature to address the expensive and time-consuming nature of experimental validation via intensity interferometry. However, the…

Our study investigates the impact of data augmentation on the performance of multivariate time series models, focusing on datasets from the UCR archive. Despite the limited size of these datasets, we achieved classification accuracy…

Machine Learning · Computer Science 2024-06-11 Romain Ilbert , Thai V. Hoang , Zonghua Zhang

Sickle Cell Disease (SCD) is a hereditary disorder of red blood cells in humans. Complications such as pain, stroke, and organ failure occur in SCD as malformed, sickled red blood cells passing through small blood vessels get trapped.…

While convolutional neural networks (CNNs) have been successfully applied to many challenging classification applications, they typically require large datasets for training. When the availability of labeled data is limited, data…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

Labeled speech data from patients with Parkinsons disease (PD) are scarce, and the statistical distributions of training and test data differ significantly in the existing datasets. To solve these problems, dimensional reduction and sample…

Machine Learning · Computer Science 2020-02-11 Xiaoheng Zhang , Yongming Li , Pin Wang , Xiaoheng Tan , Yuchuan Liu

High-dimensional time series datasets are becoming increasingly common in many areas of biological and social sciences. Some important applications include gene regulatory network reconstruction using time course gene expression data, brain…

Methodology · Statistics 2021-08-02 Sumanta Basu , David S. Matteson

In healthcare applications, temporal variables that encode movement, health status and longitudinal patient evolution are often accompanied by rich structured information such as demographics, diagnostics and medical exam data. However,…

Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…

Machine Learning · Computer Science 2018-03-05 Dev Goyal , Zeeshan Syed , Jenna Wiens

Real-world time series data that commonly reflect sequential human behavior are often uniquely irregularly sampled and sparse, with highly nonuniform sampling over time and entities. Yet, commonly-used pretraining and augmentation methods…

Machine Learning · Computer Science 2023-08-29 Nicasia Beebe-Wang , Sayna Ebrahimi , Jinsung Yoon , Sercan O. Arik , Tomas Pfister

Stochastic epidemic models describe the dynamics of an epidemic as a disease spreads through a population. Typically, only a fraction of cases are observed at a set of discrete times. The absence of complete information about the time…

Computation · Statistics 2017-02-14 Jonathan Fintzi , Xiang Cui , Jon Wakefield , Vladimir N. Minin

In clinical practice and biomedical research, measurements are often collected sparsely and irregularly in time while the data acquisition is expensive and inconvenient. Examples include measurements of spine bone mineral density, cancer…

Machine Learning · Statistics 2021-08-05 Łukasz Kidziński , Trevor Hastie

Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of…

Machine Learning · Computer Science 2020-11-18 Jinghe Zhang , Kamran Kowsari , Mehdi Boukhechba , James Harrison , Jennifer Lobo , Laura Barnes

We consider high-dimensional regression over subgroups of observations. Our work is motivated by biomedical problems, where disease subtypes, for example, may differ with respect to underlying regression models, but sample sizes at the…

Motivated by two case studies using primary care records from the Clinical Practice Research Datalink, we describe statistical methods that facilitate the analysis of tall data, with very large numbers of observations. Our focus is on…

Methodology · Statistics 2018-05-14 Kirsty Rhodes , Rebecca Turner , Rupert Payne , Ian White

Sickle Cell Disease (SCD) is a chronic genetic disorder characterized by recurrent acute painful episodes. Opioids are often used to manage these painful episodes; the extent of their use in managing pain in this disorder is an issue of…

Artificial Intelligence · Computer Science 2023-10-11 Swati Padhee , Tanvi Banerjee , Daniel M. Abrams , Nirmish Shah
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