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While Mixed-integer linear programming (MILP) is NP-hard in general, practical MILP has received roughly 100--fold speedup in the past twenty years. Still, many classes of MILPs quickly become unsolvable as their sizes increase, motivating…

Machine Learning · Computer Science 2023-05-29 Ziang Chen , Jialin Liu , Xinshang Wang , Jianfeng Lu , Wotao Yin

Mixed-integer linear programming (MILP) is widely employed for modeling combinatorial optimization problems. In practice, similar MILP instances with only coefficient variations are routinely solved, and machine learning (ML) algorithms are…

Optimization and Control · Mathematics 2023-03-07 Qingyu Han , Linxin Yang , Qian Chen , Xiang Zhou , Dong Zhang , Akang Wang , Ruoyu Sun , Xiaodong Luo

ReLU neural networks have been modelled as constraints in mixed integer linear programming (MILP), enabling surrogate-based optimisation in various domains and efficient solution of machine learning certification problems. However, previous…

Optimization and Control · Mathematics 2023-12-05 Tom McDonald , Calvin Tsay , Artur M. Schweidtmann , Neil Yorke-Smith

Mixed-integer programming (MIP) technology offers a generic way of formulating and solving combinatorial optimization problems. While generally reliable, state-of-the-art MIP solvers base many crucial decisions on hand-crafted heuristics,…

Machine Learning · Computer Science 2022-05-31 Elias B. Khalil , Christopher Morris , Andrea Lodi

Mixed-integer linear programs (MILPs) are extensively used to model practical problems such as planning and scheduling. A prominent method for solving MILPs is large neighborhood search (LNS), which iteratively seeks improved solutions…

Optimization and Control · Mathematics 2024-12-12 Wenbo Liu , Akang Wang , Wenguo Yang , Qingjiang Shi

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

Mixed Integer Linear Programs (MILPs) are highly flexible and powerful tools for modeling and solving complex real-world combinatorial optimization problems. Recently, machine learning (ML)-guided approaches have demonstrated significant…

Artificial Intelligence · Computer Science 2025-06-13 Junyang Cai , Taoan Huang , Bistra Dilkina

Mixed Integer Linear Programs (MILPs) are essential tools for solving planning and scheduling problems across critical industries such as construction, manufacturing, and logistics. However, their widespread adoption is limited by long…

Machine Learning · Computer Science 2025-06-10 Xiaoke Wang , Batuhan Altundas , Zhaoxin Li , Aaron Zhao , Matthew Gombolay

Mixed Integer programs (MIPs) are typically solved by the Branch-and-Bound algorithm. Recently, Learning to imitate fast approximations of the expert strong branching heuristic has gained attention due to its success in reducing the running…

Optimization and Control · Mathematics 2023-07-03 Sahil Manchanda , Sayan Ranu

Designing faster algorithms for solving Mixed-Integer Linear Programming (MILP) problems is highly desired across numerous practical domains, as a vast array of complex real-world challenges can be effectively modeled as MILP formulations.…

Artificial Intelligence · Computer Science 2026-01-23 Ruizhi Liu , Liming Xu , Xulin Huang , Jingyan Sui , Shizhe Ding , Boyang Xia , Chungong Yu , Dongbo Bu

The core of molecular dynamics simulation fundamentally lies in the interatomic potential. Traditional empirical potentials lack accuracy, while first-principles methods are computationally prohibitive. Machine learning interatomic…

Machine Learning · Computer Science 2026-03-25 Shuyu Bi , Zhede Zhao , Qiangchao Sun , Tao Hu , Xionggang Lu , Hongwei Cheng

Mixed-integer linear programming (MILP) stands as a notable NP-hard problem pivotal to numerous crucial industrial applications. The development of effective algorithms, the tuning of solvers, and the training of machine learning models for…

Machine Learning · Computer Science 2023-10-23 Haoyu Wang , Jialin Liu , Xiaohan Chen , Xinshang Wang , Pan Li , Wotao Yin

A recent Graph Neural Network (GNN) approach for learning to branch has been shown to successfully reduce the running time of branch-and-bound algorithms for Mixed Integer Linear Programming (MILP). While the GNN relies on a GPU for…

Machine Learning · Computer Science 2020-10-26 Prateek Gupta , Maxime Gasse , Elias B. Khalil , M. Pawan Kumar , Andrea Lodi , Yoshua Bengio

Mixed Integer Linear Programming (MILP) is essential for modeling complex decision-making problems but faces challenges in computational tractability and requires expert formulation. Current deep learning approaches for MILP focus on…

Machine Learning · Computer Science 2025-02-24 Sirui Li , Janardhan Kulkarni , Ishai Menache , Cathy Wu , Beibin Li

Mixed Integer Linear Programming (MILP) is a fundamental class of NP-hard problems that has garnered significant attention from both academia and industry. The Branch-and-Bound (B\&B) method is the dominant approach for solving MILPs and…

Machine Learning · Computer Science 2025-11-27 Tongkai Lu , Shuai Ma , Chongyang Tao

In this paper, we develop a fast mixed-integer convex programming (MICP) framework for multi-robot navigation by combining graph attention networks and distributed optimization. We formulate a mixed-integer optimization problem for receding…

Systems and Control · Electrical Eng. & Systems 2025-03-28 Viet-Anh Le , Panagiotis Kounatidis , Andreas A. Malikopoulos

Mixed Integer Linear Programming (MILP) is a pillar of mathematical optimization that offers a powerful modeling language for a wide range of applications. During the past decades, enormous algorithmic progress has been made in solving…

Optimization and Control · Mathematics 2024-02-09 Lara Scavuzzo , Karen Aardal , Andrea Lodi , Neil Yorke-Smith

By exploiting the correlation between the structure and the solution of Mixed-Integer Linear Programming (MILP), Machine Learning (ML) has become a promising method for solving large-scale MILP problems. Existing ML-based MILP solvers…

Machine Learning · Computer Science 2025-01-03 Yixuan Li , Can Chen , Jiajun Li , Jiahui Duan , Xiongwei Han , Tao Zhong , Vincent Chau , Weiwei Wu , Wanyuan Wang

Graph representation learning has rapidly emerged as a pivotal field of study. Despite its growing popularity, the majority of research has been confined to embedding single-layer graphs, which fall short in representing complex systems…

Machine Learning · Computer Science 2024-03-29 Marco Bongiovanni , Luca Gallo , Roberto Grasso , Alfredo Pulvirenti

Mixed-integer optimization is at the core of many online decision-making systems that demand frequent updates of decisions in real time. However, due to their combinatorial nature, mixed-integer linear programs (MILPs) can be difficult to…

Optimization and Control · Mathematics 2026-04-21 Shivi Dixit , Rishabh Gupta , Qi Zhang
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