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Inferring the causal relationships among a set of variables in the form of a directed acyclic graph (DAG) is an important but notoriously challenging problem. Recently, advancements in high-throughput genomic perturbation screens have…

Machine Learning · Computer Science 2025-10-03 Seong Woo Han , Daniel Duy Vo , Brielin C. Brown

Efficient signal representation is essential for the functioning of living and artificial systems operating under resource constraints. A widely recognized framework for deriving such representations is the information bottleneck method,…

Molecular Networks · Quantitative Biology 2025-07-08 Vahe Galstyan , Age Tjalma , Pieter Rein ten Wolde

Generative Bayesian Computation (GBC) methods are developed for Casual Inference. Generative methods are simulation-based methods that use a large training dataset to represent posterior distributions as a map (a.k.a. optimal transport) to…

Methodology · Statistics 2024-12-25 Maria Nareklishvili , Nicholas Polson , Vadim Sokolov

Reliable uncertainty quantification remains a central challenge in predictive modeling. While Bayesian methods are theoretically appealing, their predictive intervals can exhibit poor frequentist calibration, particularly with small sample…

Methodology · Statistics 2025-08-05 Graham Gibson

Due to the superior performance of Graph Neural Networks (GNNs) in various domains, there is an increasing interest in the GNN explanation problem "\emph{which fraction of the input graph is the most crucial to decide the model's…

Machine Learning · Computer Science 2022-07-04 Qinghua Zheng , Jihong Wang , Minnan Luo , Yaoliang Yu , Jundong Li , Lina Yao , Xiaojun Chang

Identifying variables responsible for changes to a biological system enables applications in drug target discovery and cell engineering. Given a pair of observational and interventional datasets, the goal is to isolate the subset of…

Machine Learning · Computer Science 2025-06-02 Menghua Wu , Umesh Padia , Sean H. Murphy , Regina Barzilay , Tommi Jaakkola

Instrumental variable (IV) methods are central to causal inference from observational data, particularly when a randomized experiment is not feasible. However, of the three conventional core IV identification conditions, only one, IV…

Methodology · Statistics 2025-09-23 Zhonghua Liu , Baoluo Sun , Ting Ye , David Richardson , Eric Tchetgen Tchetgen

In many problems, the measured variables (e.g., image pixels) are just mathematical functions of the latent causal variables (e.g., the underlying concepts or objects). For the purpose of making predictions in changing environments or…

Machine Learning · Computer Science 2024-08-13 Kun Zhang , Shaoan Xie , Ignavier Ng , Yujia Zheng

Identifying the underlying time-delayed latent causal processes in sequential data is vital for grasping temporal dynamics and making downstream reasoning. While some recent methods can robustly identify these latent causal variables, they…

Machine Learning · Computer Science 2024-05-31 Guangyi Chen , Yifan Shen , Zhenhao Chen , Xiangchen Song , Yuewen Sun , Weiran Yao , Xiao Liu , Kun Zhang

We propose an adversarial training procedure for learning a causal implicit generative model for a given causal graph. We show that adversarial training can be used to learn a generative model with true observational and interventional…

Machine Learning · Computer Science 2017-09-18 Murat Kocaoglu , Christopher Snyder , Alexandros G. Dimakis , Sriram Vishwanath

Graph Neural Networks (GNNs) have received increasing attention due to their ability to learn from graph-structured data. However, their predictions are often not interpretable. Post-hoc instance-level explanation methods have been proposed…

Machine Learning · Computer Science 2023-07-18 Jiaxing Zhang , Dongsheng Luo , Hua Wei

There has been a tremendous progress in Domain Adaptation (DA) for visual recognition tasks. Particularly, open-set DA has gained considerable attention wherein the target domain contains additional unseen categories. Existing open-set DA…

Computer Vision and Pattern Recognition · Computer Science 2020-04-10 Jogendra Nath Kundu , Naveen Venkat , Ambareesh Revanur , Rahul M , R. Venkatesh Babu

Human Multimodal Language Understanding (MLU) aims to infer human intentions by integrating related cues from heterogeneous modalities. Existing works predominantly follow a ``learning to attend" paradigm, which maximizes mutual information…

Computation and Language · Computer Science 2025-09-29 Menghua Jiang , Yuncheng Jiang , Haifeng Hu , Sijie Mai

Causal representation learning aims to recover the latent causal variables and their causal relations, typically represented by directed acyclic graphs (DAGs), from low-level observations such as image pixels. A prevailing line of research…

Machine Learning · Computer Science 2026-04-28 Ignavier Ng , Shaoan Xie , Xinshuai Dong , Peter Spirtes , Kun Zhang

Visual explanation methods have an important role in the prognosis of the patients where the annotated data is limited or unavailable. There have been several attempts to use gradient-based attribution methods to localize pathology from…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Ugur Demir , Ismail Irmakci , Elif Keles , Ahmet Topcu , Ziyue Xu , Concetto Spampinato , Sachin Jambawalikar , Evrim Turkbey , Baris Turkbey , Ulas Bagci

Directed acyclic graphical (DAG) models are a powerful tool for representing causal relationships among jointly distributed random variables, especially concerning data from across different experimental settings. However, it is not always…

Machine Learning · Statistics 2026-04-03 Francisco Madaleno , Pratik Misra , Alex Markham

We discuss Bayesian model uncertainty analysis and forecasting in sequential dynamic modeling of multivariate time series. The perspective is that of a decision-maker with a specific forecasting objective that guides thinking about relevant…

Methodology · Statistics 2022-06-07 Isaac Lavine , Michael Lindon , Mike West

We study the problem of globally optimising a target variable of an unknown causal graph on which a sequence of soft or hard interventions can be performed. The problem of optimising the target variable associated with a causal graph is…

Machine Learning · Computer Science 2024-11-06 Sumantrak Mukherjee , Mengyan Zhang , Seth Flaxman , Sebastian Josef Vollmer

Instrumental variable (IV) and proximal causal learning (Proxy) methods are central frameworks for causal inference in the presence of unobserved confounding. Despite substantial methodological advances, existing approaches rarely provide…

Machine Learning · Statistics 2026-03-03 Yuqi Zhang , Krikamol Muandet , Dino Sejdinovic , Edwin Fong , Siu Lun Chau

Studies show that the representations learned by deep neural networks can be transferred to similar prediction tasks in other domains for which we do not have enough labeled data. However, as we transition to higher layers in the model, the…

Machine Learning · Computer Science 2019-10-29 Raha Moraffah , Kai Shu , Adrienne Raglin , Huan Liu