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Type 2 Diabetes is a fast-growing, chronic metabolic disorder due to imbalanced insulin activity.The motion of this research is a comparative study of seven machine learning classifiers and an artificial neural network method to…

Machine Learning · Computer Science 2023-01-10 Md. Kowsher , Mahbuba Yesmin Turaba , Tanvir Sajed , M M Mahabubur Rahman

Accurately detecting hypoglycemia without invasive glucose sensors remains a critical challenge in diabetes management, particularly in regions where continuous glucose monitoring (CGM) is prohibitively expensive or clinically inaccessible.…

Human-Computer Interaction · Computer Science 2026-02-12 Lawrence Obiuwevwi , Krzysztof J. Rechowicz , Vikas Ashok , Sampath Jayarathna

Peptide compounds demonstrate considerable potential as therapeutic agents due to their high target affinity and low toxicity, yet their drug development is constrained by their low membrane permeability. Molecular weight and peptide length…

Machine Learning · Computer Science 2025-05-26 Shuang Wu , Meijie Wang , Lun Yu

Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder whose neuroimaging-based diagnosis remains challenging due to complex time-varying disruptions in brain connectivity. Functional MRI (fMRI) provides…

Machine Learning · Computer Science 2026-03-30 Qurat Ul Ain , Alptekin Temizel , Soyiba Jawed

Multivariate time series (MTS) analysis prevails in real-world applications such as finance, climate science and healthcare. The various self-attention mechanisms, the backbone of the state-of-the-art Transformer-based models, efficiently…

Machine Learning · Computer Science 2023-11-21 Quang Minh Nguyen , Lam M. Nguyen , Subhro Das

This paper proposes GluMind, a transformer-based multimodal framework designed for continual and long-term blood glucose forecasting. GluMind devises two attention mechanisms, including cross-attention and multi-scale attention, which…

Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

When modeling longitudinal biomedical data, often dimensionality reduction as well as dynamic modeling in the resulting latent representation is needed. This can be achieved by artificial neural networks for dimension reduction, and…

Machine Learning · Statistics 2023-12-01 Göran Köber , Raffael Kalisch , Lara Puhlmann , Andrea Chmitorz , Anita Schick , Harald Binder

Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce…

Machine Learning · Computer Science 2019-04-01 Neil C. Borle , Edmond A. Ryan , Russell Greiner

Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…

Genomics · Quantitative Biology 2025-05-06 Alireza Sadeghi , Farshid Hajati , Ahmadreza Argha , Nigel H Lovell , Min Yang , Hamid Alinejad-Rokny

Nowadays, the screening methods for the early detection of lung cancer struggle with several limitations such as many false positive results and low sensitivity. The detection of specific biomarkers is of high interest to complement these…

Quantitative Methods · Quantitative Biology 2021-02-19 Juul Goossens , Jente Gieghase , Elien Derveaux , Peter Adriaensens

Clustering time-series data in healthcare is crucial for clinical phenotyping to understand patients' disease progression patterns and to design treatment guidelines tailored to homogeneous patient subgroups. While rich temporal dynamics…

Machine Learning · Computer Science 2023-02-27 Yuchao Qin , Mihaela van der Schaar , Changhee Lee

This study proposes a novel perspective on multimodal deep learning for biomedical signal classification, systematically analyzing how complementary feature domains impact model performance. While fusing multiple domains often presumes…

Machine Learning · Computer Science 2025-08-05 Timothy Oladunni , Alex Wong

Understanding the complex relationships of biomarkers in diabetes is pivotal for advancing treatment strategies, a pressing need in diabetes research. This study applies Bayesian network structure learning to analyze the Shanghai Type 1 and…

Quantitative Methods · Quantitative Biology 2024-06-26 Yuyang Sun , Jingyu Lei , Panagiotis Kosmas

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Managing Type 1 Diabetes (T1D) demands constant vigilance as individuals strive to regulate their blood glucose levels and avoid dysglycemia, including hyperglycemia and hypoglycemia. Despite advances in automated insulin delivery (AID)…

Machine Learning · Computer Science 2026-02-26 Saman Khamesian , Asiful Arefeen , Maria Adela Grando , Bithika M. Thompson , Hassan Ghasemzadeh

Patient subtyping based on temporal observations can lead to significantly nuanced subtyping that acknowledges the dynamic characteristics of diseases. Existing methods for subtyping trajectories treat the evolution of clinical observations…

Machine Learning · Computer Science 2018-11-30 Nikhil Galagali , Minnan Xu-Wilson

The functional diversity in factors identified in association with non-alcoholic fatty liver disease (NAFLD) necessitates the utilization of holistic approaches to investigate the network properties of NAFLD pathogenesis. We describe the…

Molecular Networks · Quantitative Biology 2013-09-06 Adviti Naik , Damjana Rozman , Ales Belic

This work concerns the identification of the allelic sequences of the DQB1 gene of the human leukocyte antigen system conferring susceptibility to the development of insulin-dependent diabetes mellitus (IDDM) in DNA samples with no need of…

Genomics · Quantitative Biology 2011-12-13 Luca Nardo , Giovanna Tosi , Maria Bondani , Roberto S. Accolla , Alessandra Andreoni

Paediatric Acute Myeloid Leukemia is a complex adaptive ecosystem with high morbidity. Current trajectory inference algorithms struggle to predict causal dynamics in AML progression, including relapse and recurrence risk. We propose a…

Quantitative Methods · Quantitative Biology 2025-08-20 Abicumaran Uthamacumaran , Hector Zenil