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Fundamental understanding of interatomic forces in molecules must emerge from quantum mechanics, yet widely used empirical force fields rely on simplified mechanistic approximations that often fail to capture the complexity of many-body…

Phase-field modeling is an elegant and versatile computation tool to predict microstructure evolution in materials in the mesoscale regime. However, these simulations require rigorous numerical solutions of differential equations, which are…

Materials Science · Physics 2023-08-08 Owais Ahmad , Naveen Kumar , Rajdip Mukherjee , Somnath Bhowmick

Recently, the machine learning force field has emerged as a powerful atomic simulation approach for its high accuracy and low computational cost. However, its applications in the multi-component materials are relatively less. In this study,…

Materials Science · Physics 2018-07-06 Wenwen Li , Yasunobu Ando

Accurate and efficient simulation of infrared (IR) and Raman spectra is essential for molecular identification and structural analysis. Traditional quantum chemistry methods based on the harmonic approximation neglect anharmonicity and…

Chemical Physics · Physics 2025-10-07 Shengjiao Ji , Yujin Zhang , Zihan Zou , Bin Jiang , Jun Jiang , Yi Luo , Wei Hu

Machine-learning force fields can deliver accurate molecular dynamics (MD) at high computational cost. For SO(3)-equivariant models such as MACE, there is little systematic evidence on whether reduced-precision arithmetic and GPU-optimized…

Machine Learning · Computer Science 2025-10-29 Alexandre Benoit

Predicting the adsorption affinity of a small molecule to a target surface is of importance to a range of fields, from catalysis to drug delivery and human safety, but a complex task to perform computationally when taking into account the…

Chemical Physics · Physics 2022-11-16 Ian Rouse , Vladimir Lobaskin

Machine learning force fields (MLFFs) are transforming materials science and engineering by enabling the study of complex phenomena, such as those critical to battery operation. In this work, we explore the predictive capabilities of…

Materials Science · Physics 2026-04-10 Nada Alghamdi , Paolo de Angelis , Pietro Asinari , Eliodoro Chiavazzo

Coarse-grained (CG) force field methods for molecular systems are a crucial tool to simulate large biological macromolecules and are therefore essential for characterisations of biomolecular systems. While state-of-the-art deep learning…

Machine learning (ML) models hold the promise of transforming atomic simulations by delivering quantum chemical accuracy at a fraction of the computational cost. Realization of this potential would enable high-throughout, high-accuracy…

Machine learning force fields (MLFFs) promise to accurately describe the potential energy surface of molecules at the ab initio level of theory with improved computational efficiency. Within MLFFs, equivariant graph neural networks (EQNNs)…

Chemical Physics · Physics 2025-05-15 Orlando A. Mendible , Jonathan K. Whitmer , Yamil J. Colón

Spherical truncations of Coulomb interactions in standard models for water permit efficient molecular simulations and can give remarkably accurate results for the structure of the uniform liquid. However truncations are known to produce…

Statistical Mechanics · Physics 2009-11-13 Jocelyn M. Rodgers , John D. Weeks

The force field describing the calculated interaction between atoms or molecules is the key to the accuracy of many molecular dynamics (MD) simulation results. Compared with traditional or semi-empirical force fields, machine learning force…

Computational Physics · Physics 2023-06-28 Yongle Li , Feng Xu , Long Hou , Luchao Sun , Haijun Su , Xi Li , Wei Ren

In recent years, many types of machine learning potentials (MLPs) have been introduced, which are able to represent high-dimensional potential-energy surfaces (PES) with close to first-principles accuracy. Most current MLPs rely on atomic…

Materials Science · Physics 2022-04-06 Marius Herbold , Jörg Behler

We propose FMMformers, a class of efficient and flexible transformers inspired by the celebrated fast multipole method (FMM) for accelerating interacting particle simulation. FMM decomposes particle-particle interaction into near-field and…

Machine Learning · Computer Science 2021-08-06 Tan M. Nguyen , Vai Suliafu , Stanley J. Osher , Long Chen , Bao Wang

Machine-learned force fields have generated significant interest in recent years as a tool for molecular dynamics (MD) simulations, with the aim of developing accurate and efficient models that can replace classical interatomic potentials.…

Machine Learning · Computer Science 2023-04-05 Shaswat Mohanty , Sanghyuk Yoo , Keonwook Kang , Wei Cai

We investigate the impact of choosing regressors and molecular representations for the construction of fast machine learning (ML) models of thirteen electronic ground-state properties of organic molecules. The performance of each…

We present the construction of molecular force fields for small molecules (less than 25 atoms) using the recently developed symmetrized gradient-domain machine learning (sGDML) approach [Chmiela et al., Nat. Commun. 9, 3887 (2018); Sci.…

Machine learning and deep learning have revolutionized computational physics, particularly the simulation of complex systems. Equivariance is essential for simulating physical systems because it imposes a strong inductive bias on the…

Strongly Correlated Electrons · Physics 2024-11-13 Yuki Nagai , Akio Tomiya

In this study, we introduce a training protocol for developing machine learning force fields (MLFFs), capable of accurately determining energy barriers in catalytic reaction pathways. The protocol is validated on the extensively explored…

Chemical Physics · Physics 2023-08-23 Lars Schaaf , Edvin Fako , Sandip De , Ansgar Schäfer , Gábor Csányi

The growing penetration of renewable and distributed generation is transforming power systems and challenging conventional protection schemes that rely on fixed settings and local measurements. Machine learning (ML) offers a data-driven…

Machine Learning · Computer Science 2025-12-18 Julian Oelhaf , Mehran Pashaei , Georg Kordowich , Christian Bergler , Andreas Maier , Johann Jäger , Siming Bayer
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