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Despite high performance on clinical benchmarks, large language models may reach correct conclusions through faulty reasoning, a failure mode with safety implications for oncology decision support that is not captured by accuracy-based…

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Models of human feedback for AI alignment, such as those underpinning Direct Preference Optimization (DPO), often bake in a singular, static set of preferences, limiting adaptability. This paper challenges the assumption of monolithic…

Computation and Language · Computer Science 2025-06-16 Víctor Gallego

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

Large Language Models (LLMs) have demonstrated remarkable capabilities in many real-world applications. Nonetheless, LLMs are often criticized for their tendency to produce hallucinations, wherein the models fabricate incorrect statements…

Computation and Language · Computer Science 2024-06-05 Qinggang Zhang , Junnan Dong , Hao Chen , Daochen Zha , Zailiang Yu , Xiao Huang

With the recent progress of Large Language Models (LLMs), there is a growing interest in applying these models to solve complex and challenging problems. Modern LLMs, capable of processing long contexts and generating verbalized…

Computation and Language · Computer Science 2026-04-14 WonJin Yoon , Kangyu Zhu , Ian Bulovic , Autumn Sehy , Yanjun Gao , Dmitriy Dligach , Majid Afshar , Timothy A. Miller

We present a scalable, AI-powered system that identifies and extracts evidence-based behavioral nudges from unstructured biomedical literature. Nudges are subtle, non-coercive interventions that influence behavior without limiting choice,…

Large language models (LLMs) are entering clinical workflows as decision support tools, yet how they respond to explicit patient value statements -- the core content of shared decision-making -- remains unmeasured. We conducted a factorial…

Computers and Society · Computer Science 2026-03-03 Sanjay Basu

Prompt learning has become a prevalent strategy for adapting vision-language foundation models (VLMs) such as CLIP to downstream tasks. With the emergence of large language models (LLMs), recent studies have explored the potential of using…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Yubin Wang , Xinyang Jiang , De Cheng , Wenli Sun , Dongsheng Li , Cairong Zhao

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

Cross-Domain Recommendation (CDR) seeks to enhance item retrieval in low-resource domains by transferring knowledge from high-resource domains. While recent advancements in Large Language Models (LLMs) have demonstrated their potential in…

Information Retrieval · Computer Science 2025-03-12 Xinyi Liu , Ruijie Wang , Dachun Sun , Dilek Hakkani-Tur , Tarek Abdelzaher

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Although large language models (LLMs) demonstrate expert-level medical knowledge, aligning their open-ended outputs with fine-grained clinician preferences remains challenging. Existing methods often rely on coarse objectives or unreliable…

Artificial Intelligence · Computer Science 2026-02-12 Shiwei Lyu , Xidong Wang , Lei Liu , Hao Zhu , Chaohe Zhang , Jian Wang , Jinjie Gu , Benyou Wang , Yue Shen

Traditional methods for evaluating the robustness of large language models (LLMs) often rely on standardized benchmarks, which can escalate costs and limit evaluations across varied domains. This paper introduces a novel framework designed…

Computation and Language · Computer Science 2024-12-03 Aihua Pei , Zehua Yang , Shunan Zhu , Ruoxi Cheng , Ju Jia

Customized medical prompts enable Large Language Models (LLM) to effectively address medical dialogue summarization. The process of medical reporting is often time-consuming for healthcare professionals. Implementing medical dialogue…

Computation and Language · Computer Science 2024-01-22 Daphne van Zandvoort , Laura Wiersema , Tom Huibers , Sandra van Dulmen , Sjaak Brinkkemper

Large Language Models (LLMs) have shown remarkable capabilities across various domains, yet they struggle with knowledge-intensive tasks in areas that demand factual accuracy, e.g. industrial automation and healthcare. Key limitations…

Machine Learning · Computer Science 2025-09-10 Michael Banf , Johannes Kuhn

Over the past decade, the use of machine learning (ML) models in healthcare applications has rapidly increased. Despite high performance, modern ML models do not always capture patterns the end user requires. For example, a model may…

Recent studies have made remarkable progress in histopathology classification. Based on current successes, contemporary works proposed to further upgrade the model towards a more generalizable and robust direction through incrementally…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Yu Zhu , Kang Li , Lequan Yu , Pheng-Ann Heng

Constraint programming (CP) is a crucial technology for solving real-world constraint optimization problems (COPs), with the advantages of rich modeling semantics and high solving efficiency. Using large language models (LLMs) to generate…

Artificial Intelligence · Computer Science 2026-01-13 Weichun Shi , Minghao Liu , Wanting Zhang , Langchen Shi , Fuqi Jia , Feifei Ma , Jian Zhang