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Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

Quantitative Methods · Quantitative Biology 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

We analyze the dynamics of streaming stochastic gradient descent (SGD) in the high-dimensional limit when applied to generalized linear models and multi-index models (e.g. logistic regression, phase retrieval) with general data-covariance.…

Optimization and Control · Mathematics 2023-08-21 Elizabeth Collins-Woodfin , Courtney Paquette , Elliot Paquette , Inbar Seroussi

Fine-tuning-as-a-service, while commercially successful for Large Language Model (LLM) providers, exposes models to harmful fine-tuning attacks. As a widely explored defense paradigm against such attacks, unlearning attempts to remove…

Cryptography and Security · Computer Science 2025-05-23 Biao Yi , Tiansheng Huang , Baolei Zhang , Tong Li , Lihai Nie , Zheli Liu , Li Shen

We present a convergence rate analysis for biased stochastic gradient descent (SGD), where individual gradient updates are corrupted by computation errors. We develop stochastic quadratic constraints to formulate a small linear matrix…

Optimization and Control · Mathematics 2020-03-31 Bin Hu , Peter Seiler , Laurent Lessard

Large language models (LLMs) have demonstrated remarkable reasoning capability in solving mathematical problems. However, existing approaches primarily focus on improving the quality of correct training data, e.g., distilling high-quality…

Machine Learning · Computer Science 2025-06-02 Zhuoshi Pan , Yu Li , Honglin Lin , Qizhi Pei , Zinan Tang , Wei Wu , Chenlin Ming , H. Vicky Zhao , Conghui He , Lijun Wu

Recent benchmarks reveal that models for single-cell perturbation response are often outperformed by simply predicting the dataset mean. We trace this anomaly to a metric artifact: control-referenced deltas and unweighted error metrics…

The problem of model collapse has presented new challenges in iterative training of generative models, where such training with synthetic data leads to an overall degradation of performance. This paper looks at the problem from a…

Machine Learning · Statistics 2026-02-19 Soham Bakshi , Sunrit Chakraborty

Compression techniques for deep neural network models are becoming very important for the efficient execution of high-performance deep learning systems on edge-computing devices. The concept of model compression is also important for…

Simultaneous localization and mapping (SLAM) based on particle filtering has been extensively employed in indoor scenarios due to its high efficiency. However, in geometry feature-less scenes, the accuracy is severely reduced due to lack of…

Robotics · Computer Science 2025-07-28 Yanbin Li , Wei Zhang , Zhiguo Zhang , Xiaogang Shi , Ziruo Li , Mingming Zhang , Hongping Xie , Wenzheng Chi

Pretrained Large Language Models (LLMs) are prone to generating fluent yet factually incorrect text-a phenomenon known as hallucinations, undermining their reliability and utility in downstream tasks. We hypothesize that a generated text…

Computation and Language · Computer Science 2026-03-10 Koduvayur Subbalakshmi , Sabbir Hossain Ujjal , Venkata Krishna Teja Mangichetty , Nastaran Jamalipour Soofi

The widespread adoption of large language models (LLMs) necessitates reliable methods to detect LLM-generated text. We introduce SimMark, a robust sentence-level watermarking algorithm that makes LLMs' outputs traceable without requiring…

Computation and Language · Computer Science 2025-09-12 Amirhossein Dabiriaghdam , Lele Wang

Training large language models (LLMs) is highly resource-intensive due to their massive number of parameters and the overhead of optimizer states. While recent work has aimed to reduce memory consumption, such efforts often entail…

Machine Learning · Computer Science 2025-10-28 Sahar Rajabi , Nayeema Nonta , Sirisha Rambhatla

The growing complexity and diversity of news coverage have made framing analysis a crucial yet challenging task in computational social science. Traditional approaches, including manual annotation and fine-tuned models, remain limited by…

Computation and Language · Computer Science 2026-05-22 Valeria Pastorino , Jasivan A. Sivakumar , Nafise Sadat Moosavi

Despite its flexibility to learn diverse inductive biases in machine learning programs, meta learning (i.e., learning to learn) has long been recognized to suffer from poor scalability due to its tremendous compute/memory costs, training…

Machine Learning · Computer Science 2023-10-24 Sang Keun Choe , Sanket Vaibhav Mehta , Hwijeen Ahn , Willie Neiswanger , Pengtao Xie , Emma Strubell , Eric Xing

Foundation models have achieved remarkable success, yet their growing parameter counts pose significant computational and memory challenges. Low-rank factorization offers a promising route to reduce training and inference costs, but the…

Machine Learning · Computer Science 2026-02-16 Paul Janson , Edouard Oyallon , Eugene Belilovsky

Training and fine-tuning deep learning models, especially large language models (LLMs), on limited and imbalanced datasets poses substantial challenges. These issues often result in poor generalization, where models overfit to dominant…

Computation and Language · Computer Science 2025-01-14 Ashok Choudhary , Cornelius Thiels , Hojjat Salehinejad

Despite their empirical success, pushing Transformer architectures to extreme depth often leads to a paradoxical failure: representations become increasingly redundant, lose rank, and ultimately collapse. Existing explanations largely…

Machine Learning · Computer Science 2026-01-16 Haoran Su , Chenyu You

The purpose of image inpainting is to recover scratches and damaged areas using context information from remaining parts. In recent years, thanks to the resurgence of convolutional neural networks (CNNs), image inpainting task has made…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Zeyu Lu , Junjun Jiang , Junqin Huang , Gang Wu , Xianming Liu

Self-Supervised Learning (SSL) methods harness the concept of semantic invariance by utilizing data augmentation strategies to produce similar representations for different deformations of the same input. Essentially, the model captures the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Huijie Guo , Ying Ba , Jie Hu , Lingyu Si , Wenwen Qiang , Lei Shi

Various recent experimental results show that large language models (LLM) exhibit emergent abilities that are not present in small models. System performance is greatly improved after passing a certain critical threshold of scale. In this…

Computation and Language · Computer Science 2023-03-24 Cheng-Shang Chang
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