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Large language models applied to vast biological datasets have the potential to transform biology by uncovering disease mechanisms and accelerating drug development. However, current models are often siloed, trained separately on…

The integration of AI-assisted biomedical image analysis into clinical practice demands AI-generated findings that are not only accurate but also interpretable to clinicians. However, existing biomedical AI models generally lack the ability…

Multimodal large language models (MLLMs) have achieved significant success in the general field of image processing. Their emerging task generalization and freeform conversational capabilities can greatly facilitate medical diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Youzhu Jin , Yichen Zhang

Multimodal models trained on large natural image-text pair datasets have exhibited astounding abilities in generating high-quality images. Medical imaging data is fundamentally different to natural images, and the language used to…

Pathological structures in medical images are typically deviations from the expected anatomy of a patient. While clinicians consider this interplay between anatomy and pathology, recent deep learning algorithms specialize in recognizing…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Alexander Jaus , Constantin Seibold , Simon Reiß , Lukas Heine , Anton Schily , Moon Kim , Fin Hendrik Bahnsen , Ken Herrmann , Rainer Stiefelhagen , Jens Kleesiek

In clinics, a radiology report is crucial for guiding a patient's treatment. However, writing radiology reports is a heavy burden for radiologists. To this end, we present an automatic, multi-modal approach for report generation from a…

Image and Video Processing · Electrical Eng. & Systems 2022-06-02 Shuxin Yang , Xian Wu , Shen Ge , S. Kevin Zhou , Li Xiao

Chest computed tomography (CT) is central to the detection and management of thoracic disease, yet the growing scale and complexity of volumetric imaging increasingly exceed what can be addressed by scan-level prediction alone. Clinically…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuguang Bai , Mingxuan Liu , Tongxi Song , Yifei Chen , Hongjia Yang , Kasidit Anmahapong , Zihan Li , Ying Zhou , Qiyuan Tian

Multimodal large language models have advanced rapidly, but their adoption in medicine is constrained by limited domain coverage, imperfect modality alignment, and insufficient grounded reasoning. We introduce MedMO, a medical multimodal…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ankan Deria , Komal Kumar , Adinath Madhavrao Dukre , Eran Segal , Salman Khan , Imran Razzak

Humans possess spatial reasoning abilities that enable them to understand spaces through multimodal observations, such as vision and sound. Large multimodal reasoning models extend these abilities by learning to perceive and reason, showing…

Recent progress in Large Vision-Language Models (LVLMs) has enabled promising applications in medical tasks, such as report generation and visual question answering. However, existing benchmarks focus mainly on the final diagnostic answer,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hyungyung Lee , Geon Choi , Jung-Oh Lee , Hangyul Yoon , Hyuk Gi Hong , Edward Choi

We introduce the concept of "empathic grounding" in conversational agents as an extension of Clark's conceptualization of grounding in conversation in which the grounding criterion includes listener empathy for the speaker's affective…

Human-Computer Interaction · Computer Science 2024-07-03 Mehdi Arjmand , Farnaz Nouraei , Ian Steenstra , Timothy Bickmore

Target volume contouring for radiation therapy is considered significantly more challenging than the normal organ segmentation tasks as it necessitates the utilization of both image and text-based clinical information. Inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yujin Oh , Sangjoon Park , Hwa Kyung Byun , Yeona Cho , Ik Jae Lee , Jin Sung Kim , Jong Chul Ye

Radiology reports are detailed text descriptions of the content of medical scans. Each report describes the presence/absence and location of relevant clinical findings, commonly including comparison with prior exams of the same patient to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Francesco Dalla Serra , Chaoyang Wang , Fani Deligianni , Jeffrey Dalton , Alison Q O'Neil

Medical foundation models have the potential to revolutionize healthcare by providing robust and generalized representations of medical data. Medical vision-language pre-training has emerged as a promising approach for learning…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Qiao Deng , Zhongzhen Huang , Yunqi Wang , Zhichuan Wang , Zhao Wang , Xiaofan Zhang , Qi Dou , Yeung Yu Hui , Edward S. Hui

Report generation models offer fine-grained textual interpretations of medical images like chest X-rays, yet they often lack interactivity (i.e. the ability to steer the generation process through user queries) and localized…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Philip Müller , Georgios Kaissis , Daniel Rueckert

Spatial reasoning is a fundamental capability for embodied intelligence, especially for fine-grained manipulation tasks such as robotic assembly. While recent vision-language models (VLMs) exhibit preliminary spatial awareness, they largely…

Robotics · Computer Science 2026-04-13 Zhi Jing , Jinbin Qiao , Ouyang Lu , Jicong Ao , Shuang Qiu , Yu-Gang Jiang , Chenjia Bai

Chest radiograph interpretation requires temporal reasoning over prior and current studies, yet most vision-language models are trained on static image-report pairs and lack explicit supervision for modeling longitudinal change. We…

Despite recent progress, medical foundation models still struggle to unify visual understanding and generation, as these tasks have inherently conflicting goals: semantic abstraction versus pixel-level reconstruction. Existing approaches,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Ruiheng Zhang , Jingfeng Yao , Huangxuan Zhao , Hao Yan , Xiao He , Lei Chen , Zhou Wei , Yong Luo , Zengmao Wang , Lefei Zhang , Dacheng Tao , Bo Du

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Automatic radiology report generation is a promising application of multimodal deep learning, aiming to reduce reporting workload and improve consistency. However, current state-of-the-art (SOTA) systems - such as Multimodal AI for…