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At the heart of medicine lies the physician-patient dialogue, where skillful history-taking paves the way for accurate diagnosis, effective management, and enduring trust. Artificial Intelligence (AI) systems capable of diagnostic dialogue…

Numerous medical systems powered by Large Language Models (LLMs) have achieved remarkable progress in diverse healthcare tasks. However, research on their medication safety remains limited due to the lack of real world datasets, constrained…

Artificial Intelligence · Computer Science 2025-11-07 Jiahao Zhao , Luxin Xu , Minghuan Tan , Lichao Zhang , Ahmadreza Argha , Hamid Alinejad-Rokny , Min Yang

Background: Cognitive biases in clinical decision-making significantly contribute to errors in diagnosis and suboptimal patient outcomes. Addressing these biases presents a formidable challenge in the medical field. Objective: This study…

Computation and Language · Computer Science 2024-05-14 Yu He Ke , Rui Yang , Sui An Lie , Taylor Xin Yi Lim , Hairil Rizal Abdullah , Daniel Shu Wei Ting , Nan Liu

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

In recent years, interest has arisen in using machine learning to improve the efficiency of automatic medical consultation and enhance patient experience. In this article, we propose two frameworks to support automatic medical consultation,…

Computation and Language · Computer Science 2022-12-27 Wei Chen , Zhiwei Li , Hongyi Fang , Qianyuan Yao , Cheng Zhong , Jianye Hao , Qi Zhang , Xuanjing Huang , Jiajie Peng , Zhongyu Wei

With the proliferation of Large Language Models (LLMs) in diverse domains, there is a particular need for unified evaluation standards in clinical medical scenarios, where models need to be examined very thoroughly. We present CliMedBench,…

Computation and Language · Computer Science 2024-10-07 Zetian Ouyang , Yishuai Qiu , Linlin Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Online health resources and large language models (LLMs) are increasingly used as a first point of contact for medical decision-making, yet their reliability in healthcare remains limited by low accuracy, lack of transparency, and…

Artificial Intelligence · Computer Science 2026-04-22 Yujia Liu , Sophia Yu , Hongyue Jin , Jessica Wen , Alexander Qian , Terrence Lee , Mattheus Ramsis , Gi Won Choi , Lianhui Qin , Xin Liu , Edward J. Wang

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this…

Computation and Language · Computer Science 2023-12-21 Yan Cai , Linlin Wang , Ye Wang , Gerard de Melo , Ya Zhang , Yanfeng Wang , Liang He

Large Language Models (LLMs) have shown impressive performance on existing medical question-answering benchmarks. This high performance makes it increasingly difficult to meaningfully evaluate and differentiate advanced methods. We present…

Computation and Language · Computer Science 2025-03-21 Xiangru Tang , Daniel Shao , Jiwoong Sohn , Jiapeng Chen , Jiayi Zhang , Jinyu Xiang , Fang Wu , Yilun Zhao , Chenglin Wu , Wenqi Shi , Arman Cohan , Mark Gerstein

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

An effective healthcare agent must be able to recall and reason over a patient's longitudinal medical history. However, the absence of datasets with realistic long-term dialogue timelines limits systematic evaluation. Real clinical text is…

Computation and Language · Computer Science 2026-05-20 Hebin Hu , Renke Dai , Ah-Hwee Tan , Yilin Kang

As opposed to evaluating computation and logic-based reasoning, current benchmarks for evaluating large language models (LLMs) in medicine are primarily focused on question-answering involving domain knowledge and descriptive reasoning.…

The rapid advancement of speech-to-speech (S2S) large language models (LLMs) has significantly improved real-time spoken interaction. However, current evaluation frameworks remain inadequate for assessing performance in complex, multi-turn…

Computation and Language · Computer Science 2025-09-16 Yuhao Du , Qianwei Huang , Guo Zhu , Zhanchen Dai , Shunian Chen , Qiming Zhu , Le Pan , Minghao Chen , Yuhao Zhang , Li Zhou , Benyou Wang , Haizhou Li

While Large Language Models (LLMs) excel on standardized medical exams, high scores often fail to translate to high-quality responses for real-world medical queries. Current evaluations rely heavily on multiple-choice questions, failing to…

Background: Recent advancements in large language models (LLMs) offer potential benefits in healthcare, particularly in processing extensive patient records. However, existing benchmarks do not fully assess LLMs' capability in handling…

The escalating global mental health crisis, marked by persistent treatment gaps, availability, and a shortage of qualified therapists, positions Large Language Models (LLMs) as a promising avenue for scalable support. While LLMs offer…

Large Language Models (LLMs) have made significant progress in various fields. However, challenges remain in Multi-Disciplinary Team (MDT) medical consultations. Current research enhances reasoning through role assignment, task…

Artificial Intelligence · Computer Science 2025-03-19 Kai Chen , Xinfeng Li , Tianpei Yang , Hewei Wang , Wei Dong , Yang Gao

Large language models (LLMs) have achieved remarkable breakthroughs in new dialogue capabilities by leveraging instruction tuning, which refreshes human impressions of dialogue systems. The long-standing goal of dialogue systems is to be…

Computation and Language · Computer Science 2024-04-01 Jiao Ou , Junda Lu , Che Liu , Yihong Tang , Fuzheng Zhang , Di Zhang , Kun Gai

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

We present Doctorina MedBench, a comprehensive evaluation framework for agent-based medical AI based on the simulation of realistic physician-patient interactions. Unlike traditional medical benchmarks that rely on solving standardized test…

Computation and Language · Computer Science 2026-03-30 Anna Kozlova , Stanislau Salavei , Pavel Satalkin , Hanna Plotnitskaya , Sergey Parfenyuk