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Deep neural-network-based language models (LMs) are increasingly applied to large-scale protein sequence data to predict protein function. However, being largely black-box models and thus challenging to interpret, current protein LM…

Quantitative Methods · Quantitative Biology 2024-08-06 Mai Ha Vu , Rahmad Akbar , Philippe A. Robert , Bartlomiej Swiatczak , Victor Greiff , Geir Kjetil Sandve , Dag Trygve Truslew Haug

Diadochokinetic speech tasks (DDK), in which participants repeatedly produce syllables, are commonly used as part of the assessment of speech motor impairments. These studies rely on manual analyses that are time-intensive, subjective, and…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-30 Yael Segal , Kasia Hitczenko , Matthew Goldrick , Adam Buchwald , Angela Roberts , Joseph Keshet

In this paper we propose augmenting Vision Transformer models with learnable memory tokens. Our approach allows the model to adapt to new tasks, using few parameters, while optionally preserving its capabilities on previously learned tasks.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Mark Sandler , Andrey Zhmoginov , Max Vladymyrov , Andrew Jackson

Repetitive DNA sequences underpin genome architecture and evolutionary processes, yet they remain challenging to classify accurately. Terrier is a deep learning model designed to overcome these challenges by classifying repetitive DNA…

Genomics · Quantitative Biology 2025-07-10 Robert Turnbull , Neil D. Young , Edoardo Tescari , Lee F. Skerratt , Tiffany A. Kosch

Molecular representation learning has become a central approach in AI-driven drug discovery, yet existing molecular tokenizations such as SMILES remain largely syntactic and do not naturally align with chemically meaningful substructures.…

Machine Learning · Computer Science 2026-05-19 Takayuki Kimura

Masked language modeling, widely used in discriminative language model (e.g., BERT) pretraining, commonly adopts a random masking strategy. However, random masking does not consider the importance of the different words in the sentence…

Computation and Language · Computer Science 2023-05-25 Qihuang Zhong , Liang Ding , Juhua Liu , Bo Du , Dacheng Tao

Resampling is a key component of sample-based recursive state estimation in particle filters. Recent work explores differentiable particle filters for end-to-end learning. However, resampling remains a challenge in these works, as it is…

Machine Learning · Computer Science 2020-04-28 Michael Zhu , Kevin Murphy , Rico Jonschkowski

Tokenization sits at the boundary between high-throughput genomic input and GPU compute, posing challenges in both algorithm design and system throughput. Overlapping k-mer tokenization can introduce information leakage under masked…

Genomics · Quantitative Biology 2026-01-12 Eliatan Niktab , Hardip Patel

Subword tokenization is a commonly used input pre-processing step in most recent NLP models. However, it limits the models' ability to leverage end-to-end task learning. Its frequency-based vocabulary creation compromises tokenization in…

Computation and Language · Computer Science 2022-04-25 Md Mofijul Islam , Gustavo Aguilar , Pragaash Ponnusamy , Clint Solomon Mathialagan , Chengyuan Ma , Chenlei Guo

For the semantic segmentation of images, state-of-the-art deep neural networks (DNNs) achieve high segmentation accuracy if that task is restricted to a closed set of classes. However, as of now DNNs have limited ability to operate in an…

Computer Vision and Pattern Recognition · Computer Science 2022-09-13 Svenja Uhlemeyer , Matthias Rottmann , Hanno Gottschalk

Most neural-network based speaker-adaptive acoustic models for speech synthesis can be categorized into either layer-based or input-code approaches. Although both approaches have their own pros and cons, most existing works on speaker…

Audio and Speech Processing · Electrical Eng. & Systems 2018-10-02 Hieu-Thi Luong , Junichi Yamagishi

Modern language models are internally -- and mathematically -- distributions over $\it{token}$ strings rather than $\it{character}$ strings, posing numerous challenges for programmers building user applications on top of them. For example,…

Computation and Language · Computer Science 2025-06-11 Tim Vieira , Ben LeBrun , Mario Giulianelli , Juan Luis Gastaldi , Brian DuSell , John Terilla , Timothy J. O'Donnell , Ryan Cotterell

Models based on deep convolutional neural networks (CNN) have significantly improved the performance of semantic segmentation. However, learning these models requires a large amount of training images with pixel-level labels, which are very…

Computer Vision and Pattern Recognition · Computer Science 2018-02-05 Linwei Ye , Zhi Liu , Yang Wang

Commonly-used transformer language models depend on a tokenization schema which sets an unchangeable subword vocabulary prior to pre-training, destined to be applied to all downstream tasks regardless of domain shift, novel word formations,…

Computation and Language · Computer Science 2021-08-03 Yuval Pinter , Amanda Stent , Mark Dredze , Jacob Eisenstein

As opposed to general English, many concepts in biomedical terminology have been designed in recent history by biomedical professionals with the goal of being precise and concise. This is often achieved by concatenating meaningful…

Computation and Language · Computer Science 2023-07-11 Bernal Jiménez Gutiérrez , Huan Sun , Yu Su

Applying the Transformer architecture on the character level usually requires very deep architectures that are difficult and slow to train. These problems can be partially overcome by incorporating a segmentation into tokens in the model.…

Computation and Language · Computer Science 2020-09-30 Jindřich Libovický , Alexander Fraser

Deep neural networks have achieved strong performance in genomic sequence classification; however, relating their predictions to biologically meaningful sequence patterns remains challenging. In this work, we present AttnGen, an…

Machine Learning · Computer Science 2026-05-15 Rayhaneh Shabani Nia , Ali Karkehabadi

Pre-trained language models have achieved promising performance on general benchmarks, but underperform when migrated to a specific domain. Recent works perform pre-training from scratch or continual pre-training on domain corpora. However,…

Computation and Language · Computer Science 2022-11-02 Dou Hu , Xiaolong Hou , Xiyang Du , Mengyuan Zhou , Lianxin Jiang , Yang Mo , Xiaofeng Shi

Even though deep neural networks have shown tremendous success in countless applications, explaining model behaviour or predictions is an open research problem. In this paper, we address this issue by employing a simple yet effective method…

Computer Vision and Pattern Recognition · Computer Science 2023-01-12 Ryan Benkert , Oluwaseun Joseph Aribido , Ghassan AlRegib

Compositional generalization is a basic mechanism in human language learning, which current neural networks struggle with. A recently proposed Disentangled sequence-to-sequence model (Dangle) shows promising generalization capability by…

Computation and Language · Computer Science 2022-12-13 Hao Zheng , Mirella Lapata