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The synthesis of a metasurface exhibiting a specific set of desired scattering properties is a time-consuming and resource-demanding process, which conventionally relies on many cycles of full-wave simulations. It requires an experienced…

Signal Processing · Electrical Eng. & Systems 2021-09-15 Parinaz Naseri , Sean V. Hum

Generative models for materials have achieved strong performance on periodic bulk crystals, yet their ability to generalize across scale transitions to finite nanostructures remains largely untested. We introduce Crystal-to-Nanoparticle…

Materials Science · Physics 2026-01-28 Can Polat , Erchin Serpedin , Mustafa Kurban , Hasan Kurban

In the recent decade, computational tools have become central in material design, allowing rapid development cycles at reduced costs. Machine learning tools are especially on the rise in photonics. However, the inversion of the Maxwell…

High-level synthesis (HLS) has significantly advanced the automation of digital circuits design, yet the need for expertise and time in pragma tuning remains challenging. Existing solutions for the design space exploration (DSE) adopt…

Hardware Architecture · Computer Science 2025-04-14 Ping Chang , Tosiron Adegbija , Yuchao Liao , Claudio Talarico , Ao Li , Janet Roveda

Although large language models (LLMs) have recently achieved remarkable performance on various complex reasoning benchmarks, the academic community still lacks an in-depth understanding of base model training processes and data quality. To…

Computation and Language · Computer Science 2025-05-14 Xiaoyu Tian , Sitong Zhao , Haotian Wang , Shuaiting Chen , Yiping Peng , Yunjie Ji , Han Zhao , Xiangang Li

Microstructural materials design is one of the most important applications of inverse modeling in materials science. Generally speaking, there are two broad modeling paradigms in scientific applications: forward and inverse. While the…

Machine Learning · Computer Science 2021-01-27 Zijiang Yang , Dipendra Jha , Arindam Paul , Wei-keng Liao , Alok Choudhary , Ankit Agrawal

The conventional approach to nanophotonic metasurface design and optimization for a targeted electromagnetic response involves exploring large geometry and material spaces, which is computationally costly, time consuming and a highly…

Optics · Physics 2020-05-27 Abhishek Mall , Abhijeet Patil , Amit Sethi , Anshuman Kumar

The field of DNA nanotechnology has made it possible to assemble, with high yields, different structures that have actionable properties. For example, researchers have created components that can be actuated. An exciting next step is to…

Machine Learning · Computer Science 2021-02-01 Emma Benjaminson , Rebecca E. Taylor , Matthew Travers

Inverse protein folding, the process of designing sequences that fold into a specific 3D structure, is crucial in bio-engineering and drug discovery. Traditional methods rely on experimentally resolved structures, but these cover only a…

Biomolecules · Quantitative Biology 2023-11-27 Igor Melnyk , Aurelie Lozano , Payel Das , Vijil Chenthamarakshan

Single-photon emitters (SPEs) based on nitrogen-vacancy centers in nanodiamonds (neutral NV0 (wavelength 575 nm) and negative NV- (wavelength 637 nm)) represent promising platforms for quantum nanophotonics applications, yet their emission…

Optics · Physics 2025-11-20 Omar A. M. Abdelraouf

Generative deep learning is powering a wave of new innovations in materials design. In this article, we discuss the basic operating principles of these methods and their advantages over rational design through the lens of a case study on…

Generative models are powerful tools for sampling from a learned distribution $\mathcal{P}(Y \mid X)$, and inverse-design methods invert this map to find an input $x$ that produces a desired point output $y^*$. However, many design goals…

Machine Learning · Computer Science 2026-05-12 Ori Meidler , Shaul Tolkovsky , Or Zuk

Electrospinning is a powerful technique for producing micro to nanoscale fibers with application specific architectures. Small variations in solution or operating conditions can shift the jet regime, generating non Gaussian fiber diameter…

Machine Learning · Computer Science 2026-02-11 Elisa Roldan , Tasneem Sabir

The inverse design of materials with specific desired properties, such as high-temperature superconductivity, represents a formidable challenge in materials science due to the vastness of chemical and structural space. We present a guided…

Inverse design is a common yet challenging engineering problem, particularly for nonlinear functional responses such as mechanical behavior or spectral analysis. Deep generative models are motivated by intractability, non-existence or…

Computational Engineering, Finance, and Science · Computer Science 2025-10-09 Haoxuan Dylan Mu , Mingjian Tang , Wei Gao , Wei "Wayne" Chen

The development of new materials typically involves a process of trial and error, guided by insights from past experimental and theoretical findings. The inverse design approach for soft-matter systems has the potential to optimize specific…

Realizing general inverse design could greatly accelerate the discovery of new materials with user-defined properties. However, state-of-the-art generative models tend to be limited to a specific composition or crystal structure. Herein, we…

Large language models (LLMs) have become a dominant and important tool for NLP researchers in a wide range of tasks. Today, many researchers use LLMs in synthetic data generation, task evaluation, fine-tuning, distillation, and other…

Computation and Language · Computer Science 2024-05-29 Ajay Patel , Colin Raffel , Chris Callison-Burch

The rational design of novel polymers with tailored material properties has been a long-standing challenge in the field due to the large number of possible polymer design variables. To accelerate this design process, there is a critical…

Soft Condensed Matter · Physics 2025-04-11 Vinson Liao , Arthi Jayaraman

Analysis of chemical graphs is a major research topic in computational molecular biology due to its potential applications to drug design. One approach is inverse quantitative structure activity/property relationship (inverse QSAR/QSPR)…

Data Structures and Algorithms · Computer Science 2020-09-22 Naveed Ahmed Azam , Jianshen Zhu , Yanming Sun , Yu Shi , Aleksandar Shurbevski , Liang Zhao , Hiroshi Nagamochi , Tatsuya Akutsu