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Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey

Persistent homology is a tool that can be employed to summarize the shape of data by quantifying homological features. When the data is an object in $\mathbb{R}^d$, the (augmented) persistent homology transform ((A)PHT) is a family of…

Computational Geometry · Computer Science 2022-12-27 Brittany Terese Fasy , Samuel Micka , David L. Millman , Anna Schenfisch , Lucia Williams

Persistent homology (PH) is a rigorous mathematical theory that provides a robust descriptor of data in the form of persistence diagrams (PDs) which are 2D multisets of points. Their variable size makes them, however, difficult to combine…

Machine Learning · Statistics 2019-06-14 Bartosz Zielinski , Michal Lipinski , Mateusz Juda , Matthias Zeppelzauer , Pawel Dlotko

How can we detect when global events fundamentally reshape public discourse? This study introduces a topological framework for identifying structural change in media narratives using persistent homology. Drawing on international news…

Social and Information Networks · Computer Science 2025-06-19 Mark M. Bailey , Mark I. Heiligman

RS Oph is a symbiotic recurrent nova containing a massive white dwarf with heavy mass loss during activity. In August 2021, it underwent its seventh optical eruption since the end of the 19th century. The goal of this work is to analyse the…

Tipping points are abrupt, drastic, and often irreversible changes in the evolution of non-stationary and chaotic dynamical systems. For instance, increased greenhouse gas concentrations are predicted to lead to drastic decreases in low…

Persistent homology (PH) is a method used in topological data analysis (TDA) to study qualitative features of data that persist across multiple scales. It is robust to perturbations of input data, independent of dimensions and coordinates,…

Algebraic Topology · Mathematics 2017-09-13 Nina Otter , Mason A. Porter , Ulrike Tillmann , Peter Grindrod , Heather A. Harrington

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

Topological Data Analysis (TDA) is a rising field of computational topology in which the topological structure of a data set can be observed by persistent homology. By considering a sequence of sublevel sets, one obtains a filtration that…

Methodology · Statistics 2020-03-17 Yu-Min Chung , William Cruse , Austin Lawson

We introduce the Overlap-Weighted Hierarchical Normalized Persistence Velocity (OW-HNPV), a novel topological data analysis method for detecting anomalies in time-varying networks. Unlike existing methods that measure cumulative topological…

Machine Learning · Computer Science 2025-12-18 Omid Khormali

Many datasets can be viewed as a noisy sampling of an underlying space, and tools from topological data analysis can characterize this structure for the purpose of knowledge discovery. One such tool is persistent homology, which provides a…

In this review I summarize the observational attempts done so far to unveil the nature of the progenitor system/s of Type Ia Supernovae. In particular, I focus on the most recent developments that followed the alleged detection of…

Solar and Stellar Astrophysics · Physics 2011-09-28 Ferdinando Patat

Graph neural networks have become the default choice by practitioners for graph learning tasks such as graph classification and node classification. Nevertheless, popular graph neural network models still struggle to capture higher-order…

Machine Learning · Computer Science 2024-11-27 Davide Buffelli , Farzin Soleymani , Bastian Rieck

Convection is a well-studied topic in fluid dynamics, yet it is less understood in the context of networks flows. Here, we incorporate techniques from topological data analysis (namely, persistent homology) to automate the detection and…

Dynamical Systems · Mathematics 2022-03-15 Minh Quang Le , Dane Taylor

A long-standing question related to nova eruptions is how these eruptions can lead to the formation of dust despite the ostensibly inhospitable environment for dust within the hot, irradiated ejecta. Novae in systems such as the symbiotic…

Solar and Stellar Astrophysics · Physics 2023-12-06 Y. Nikolov , G. J. M. Luna , K. A. Stoyanov , G. Borisov , K. Mukai , J. L. Sokoloski , A. Avramova-Boncheva

Persistent homology computes the multiscale topology of a data set by using a sequence of discrete complexes. In this paper, we propose that persistent homology may be a useful tool for studying the structure of the landscape of string…

High Energy Physics - Theory · Physics 2019-04-24 Alex Cole , Gary Shiu

The machinery of topological data analysis becomes increasingly popular in a broad range of machine learning tasks, ranging from anomaly detection and manifold learning to graph classification. Persistent homology is one of the key…

Point-cloud persistent homology (PH) -- computing alpha or Rips complexes on spin-position point clouds -- has been widely applied to detect phase transitions in classical spin models since Donato et al. (2016), with subsequent studies…

Statistical Mechanics · Physics 2026-04-01 Matthew Loftus

RS Ophiuchi is a symbiotic variable and a recurrent nova. We have monitored it with the Nordic Optical Telescope and obtained 30 high resolution (R=46 000) optical spectra over one orbital cycle during quiescence. To our knowledge this is…

Solar and Stellar Astrophysics · Physics 2016-10-12 A. Somero , P. Hakala , G. A. Wynn

The paper introduces a novel topological method for prediction and modeling for a nonlinear time--series that exhibit recurring patterns. According to the model, global manifold of the reconstructed state--space can be approximated by a few…

Chaotic Dynamics · Physics 2017-11-21 Sajini Anand P S , Prabhakar G Vaidya
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