English
Related papers

Related papers: Predicting Early and Complete Drug Release from Lo…

200 papers

Precise attribute intensity control--generating Large Language Model (LLM) outputs with specific, user-defined attribute intensities--is crucial for AI systems adaptable to diverse user expectations. Current LLM alignment methods, however,…

Artificial Intelligence · Computer Science 2026-02-19 Rongzhi Zhang , Liqin Ye , Yuzhao Heng , Xiang Chen , Tong Yu , Lingkai Kong , Sudheer Chava , Chao Zhang

Agents powered by large language models (LLMs) have demonstrated strong planning and decision-making capabilities in complex embodied environments. However, such agents often suffer from inefficiencies in multi-turn interactions, frequently…

Computation and Language · Computer Science 2025-09-23 Qingyu Lu , Liang Ding , Siyi Cao , Xuebo Liu , Kanjian Zhang , Jinxia Zhang , Dacheng Tao

Large language models (LLMs) have demonstrated broad utility across molecular domains, spanning drug discovery and materials design. Analyzing LLMs' latent representations is crucial for elucidating their underlying mechanisms, improving…

Machine Learning · Computer Science 2026-02-03 Zhuoran Li , Xu Sun , Wanyu Lin , Jiannong Cao

Introduction: One of the most important tasks in the Emergency Department (ED) is to promptly identify the patients who will benefit from hospital admission. Machine Learning (ML) techniques show promise as diagnostic aids in healthcare.…

Electronic Health Records (EHRs) often lack explicit links between medications and diagnoses, making clinical decision-making and research more difficult. Even when links exist, diagnosis lists may be incomplete, especially during early…

Computation and Language · Computer Science 2025-03-31 Dina Albassam , Adam Cross , Chengxiang Zhai

Advanced manufacturing with new bio-derived materials can be achieved faster and more economically with first-principle-based artificial intelligence and machine learning (AI/ML)-derived models and process optimization. Not only is this…

Soft Condensed Matter · Physics 2026-02-20 Rigoberto Advincula , Jihua Chen

Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity…

Machine Learning · Statistics 2019-08-27 Sepideh Emam , Amy X. Du , Philip Surmanowicz , Simon F. Thomsen , Russ Greiner , Robert Gniadecki

In light of the NIMH's Research Domain Criteria (RDoC), the advent of functional neuroimaging, novel technologies and methods provide new opportunities to develop precise and personalized prognosis and diagnosis of mental disorders. Machine…

Machine Learning · Computer Science 2022-07-13 Zhe Sage Chen , Prathamesh , Kulkarni , Isaac R. Galatzer-Levy , Benedetta Bigio , Carla Nasca , Yu Zhang

Amorphous particulate matter constitutes a wide range of natural and synthetic materials. Despite this ubiquity, the way in which these systems' disordered microstructure couples to their often subtle and complex dynamical behavior is not…

Soft Condensed Matter · Physics 2026-03-09 Erin G. Teich , Jason Z. Kim , Dani S. Bassett

Modeling a system's temporal behaviour in reaction to external stimuli is a fundamental problem in many areas. Pure Machine Learning (ML) approaches often fail in the small sample regime and cannot provide actionable insights beyond…

Machine Learning · Computer Science 2021-06-18 Zhaozhi Qian , William R. Zame , Lucas M. Fleuren , Paul Elbers , Mihaela van der Schaar

Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and…

Industrial Cyber-Physical Systems (CPS) are sensitive infrastructure from both safety and economics perspectives, making their reliability critically important. Machine Learning (ML), specifically deep learning, is increasingly integrated…

Machine Learning · Computer Science 2026-04-09 Annemarie Jutte , Uraz Odyurt

The recent boom of large language models (LLMs) has re-ignited the hope that artificial intelligence (AI) systems could aid medical diagnosis. Yet despite dazzling benchmark scores, LLM assistants have yet to deliver measurable improvements…

Artificial Intelligence · Computer Science 2025-07-03 Matthew JY Kang , Wenli Yang , Monica R Roberts , Byeong Ho Kang , Charles B Malpas

ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics…

Machine Learning · Computer Science 2019-10-08 Zhiheng Li , Xinyue Xing , Bingzhang Lu , Zhixiang Li

As organizations increasingly seek to leverage machine learning (ML) capabilities, the technical complexity of implementing ML solutions creates significant barriers to adoption and impacts operational efficiency. This research examines how…

Human-Computer Interaction · Computer Science 2025-07-09 Jiapeng Yao , Lantian Zhang , Jiping Huang

Acute Myeloid Leukemia (AML) is one of the most aggressive types of hematological neoplasm. To support the specialists' decision about the appropriate therapy, patients with AML receive a prognostic of outcomes according to their…

Machine Learning · Computer Science 2024-05-30 Jade M. Almeida , Giovanna A. Castro , João A. Machado-Neto , Tiago A. Almeida

Large language models (LLMs) have demonstrated potential in the innovation of many disciplines. However, how they can best be developed for oncology remains underdeveloped. State-of-the-art OpenAI models were fine-tuned on a clinical…

Artificial Intelligence · Computer Science 2024-06-17 Tristen Pool , Dennis Trujillo

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large Language Models (LLMs) have shown promise in clinical applications through prompt engineering, allowing flexible clinical predictions. However, they struggle to produce reliable prediction probabilities, which are crucial for…

Artificial Intelligence · Computer Science 2024-12-05 Bowen Gu , Rishi J. Desai , Kueiyu Joshua Lin , Jie Yang

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong