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This paper presents a distributed data-driven predictive control (DDPC) approach using the behavioral framework. It aims to design a network of controllers for an interconnected system with linear time-invariant (LTI) subsystems such that a…

Systems and Control · Electrical Eng. & Systems 2024-02-15 Yitao Yan , Jie Bao , Biao Huang

Many systems are subject to periodic disturbances and exhibit repetitive behaviour. Model-based repetitive control employs knowledge of such periodicity to attenuate periodic disturbances and has seen a wide range of successful industrial…

Systems and Control · Electrical Eng. & Systems 2024-08-28 Rogier Dinkla , Tom Oomen , Sebastiaan Mulders , Jan-Willem van Wingerden

The high energy consumption of buildings presents a critical need for advanced control strategies like Demand Response (DR). Differentiable Predictive Control (DPC) has emerged as a promising method for learning explicit control policies,…

Systems and Control · Electrical Eng. & Systems 2026-03-24 Kaipeng Xu , Zhuo Zhi , Ruixuan Zhao , Keyue Jiang

Deep generative models have been widely used for their ability to generate realistic data samples in various areas, such as images, molecules, text, and speech. One major goal of data generation is controllability, namely to generate new…

Machine Learning · Computer Science 2023-10-12 Bo Pan , Muran Qin , Shiyu Wang , Yifei Zhang , Liang Zhao

In tumoral cells, gene regulation mechanisms are severely altered, and these modifications in the regulations may be characteristic of different subtypes of cancer. However, these alterations do not necessarily induce differential…

Controllable Dialogue Generation (CDG) enables chatbots to generate responses with desired attributes, and weighted decoding methods have achieved significant success in the CDG task. However, using a fixed constant value to manage the bias…

Computation and Language · Computer Science 2025-11-04 Seungmin Shin , Dooyoung Kim , Youngjoong Ko

Model Predictive Control (MPC) is an enabling technology in applications requiring controlling physical processes in an optimized way under constraints on inputs and outputs. However, in MPC closed-loop performance is pushed to the limits…

Optimization and Control · Mathematics 2019-05-06 Dario Piga , Marco Forgione , Simone Formentin , Alberto Bemporad

We design a two-component controller to achieve reference tracking with output constraints - exemplified on systems of relative degree two. One component is a data-driven or learning-based predictive controller, which uses data samples to…

Optimization and Control · Mathematics 2025-05-27 Lea Bold , Lukas Lanza , Karl Worthmann

Based on the extension of the behavioral theory and the Fundamental Lemma for Linear Parameter-Varying (LPV) systems, this paper introduces a Data-driven Predictive Control (DPC) scheme capable to ensure reference tracking and satisfaction…

Systems and Control · Electrical Eng. & Systems 2022-01-25 Chris Verhoek , Hossam S. Abbas , Roland Tóth , Sofie Haesaert

This beta technical report asks how reusable experience should be represented so that it can function as effective test-time control and as a substrate for iterative evolution. We study this question in 4.590 controlled trials across 45…

Software Engineering · Computer Science 2026-04-17 Junjie Wang , Yiming Ren , Haoyang Zhang

We study the problem of extrapolative controlled generation, i.e., generating sequences with attribute values beyond the range seen in training. This task is of significant importance in automated design, especially drug discovery, where…

Machine Learning · Computer Science 2023-06-08 Vishakh Padmakumar , Richard Yuanzhe Pang , He He , Ankur P. Parikh

Motivation: Histone modifications are among the most important factors that control gene regulation. Computational methods that predict gene expression from histone modification signals are highly desirable for understanding their…

Machine Learning · Computer Science 2016-07-08 Ritambhara Singh , Jack Lanchantin , Gabriel Robins , Yanjun Qi

Microarrays are made it possible to simultaneously monitor the expression profiles of thousands of genes under various experimental conditions. Identification of co-expressed genes and coherent patterns is the central goal in microarray or…

Computational Engineering, Finance, and Science · Computer Science 2013-07-15 T. Chandrasekhar , K. Thangavel , E. Elayaraja , E. N. Sathishkumar

Gene regulation is an important fundamental biological process. The regulation of gene expression is managed through a variety of methods including epigenetic processes (e.g., DNA methylation). Understanding the role of epigenetic changes…

Molecular Networks · Quantitative Biology 2021-06-01 James Brunner , Jacob Kim , Timothy Downing , Eric Mjolsness , Kord M. Kober

Data-driven predictive control (DPC) is becoming an attractive alternative to model predictive control as it requires less system knowledge for implementation and reliable data is increasingly available in smart engineering systems. Two…

Optimization and Control · Mathematics 2023-04-05 M. Lazar , P. C. N. Verheijen

We consider the problem of predicting gene expressions from DNA sequences. A key challenge of this task is to find the regulatory elements that control gene expressions. Here, we introduce Seq2Exp, a Sequence to Expression network…

Genomics · Quantitative Biology 2025-02-21 Xingyu Su , Haiyang Yu , Degui Zhi , Shuiwang Ji

This paper presents a Model-Inspired Distributionally Robust Data-enabled Predictive Control (MDR-DeePC) framework for systems with partially known and uncertain dynamics. The proposed method integrates model-based equality constraints for…

Systems and Control · Electrical Eng. & Systems 2025-07-01 Shihao Li , Jiachen Li , Christopher Martin , Soovadeep Bakshi , Dongmei Chen

In this letter, we propose a simple yet effective singular value decomposition (SVD) based strategy to reduce the optimization problem dimension in data-enabled predictive control (DeePC). Specifically, in the case of linear time-invariant…

Systems and Control · Electrical Eng. & Systems 2023-10-09 Kaixiang Zhang , Yang Zheng , Chao Shang , Zhaojian Li

Data-driven control methods such as data-enabled predictive control (DeePC) have shown strong potential in efficient control of soft robots without explicit parametric models. However, in object manipulation tasks, unknown external payloads…

Robotics · Computer Science 2025-10-07 Huanqing Wang , Kaixiang Zhang , Kyungjoon Lee , Yu Mei , Vaibhav Srivastava , Jun Sheng , Ziyou Song , Zhaojian Li

Willems' fundamental lemma has recently received an impressive amount of attention from the data-driven control community. In this paper, we formulate a version of this celebrated result based on frequency-domain data. In doing so, we…

Optimization and Control · Mathematics 2026-02-09 T. J. Meijer , K. J. A. Scheres , S. A. N. Nouwens , V. S. Dolk , W. P. M. H. Heemels