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Phenotyping consists in applying algorithms to identify individuals associated with a specific, potentially complex, trait or condition, typically out of a collection of Electronic Health Records (EHRs). Because a lot of the clinical…

Electronic Health Records (EHRs) contain a large volume of heterogeneous patient data, which are useful at the point of care and for retrospective research. These data are typically stored in relational databases. Gaining an integrated view…

Computers and Society · Computer Science 2018-06-04 Dina Levy-Lambert , Jen J. Gong , Tristan Naumann , Tom J. Pollard , John V. Guttag

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

Information Retrieval · Computer Science 2024-09-13 Abderrahim Oussama Batouche , Eugen Czeizler , Miika Koskinen , Tuomas Mirtti , Antti Sakari Rannikko

Multi-institutional electronic health record (Multi-EHR) data have emerged as a powerful resource for developing predictive models to support clinical decisions and for generating reliable real-world evidence. By aggregating information…

Methodology · Statistics 2026-05-12 Yuming Zhang , Congyuan Duan , Dong Xia , Doudou Zhou , Tianxi Cai

Feature engineering for Electronic Health Records (EHR) is complicated by irregular observation intervals, variable measurement frequencies, and structural sparsity inherent to clinical time series. Existing automated methods either lack…

Machine Learning · Computer Science 2026-04-27 Hojjat Karami , David Atienza , Jean-Philippe Thiran , Anisoara Ionescu

Electronic health record (EHR) systems present clinicians with vast repositories of clinical information, creating a significant cognitive burden where critical details are easily overlooked. While Large Language Models (LLMs) offer…

Computation and Language · Computer Science 2026-03-17 Samuel Thio , Matthew Lewis , Spiros Denaxas , Richard JB Dobson

With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

Manual chart review remains an extremely time-consuming and resource-intensive component of clinical research, requiring experts to extract often complex information from unstructured electronic health record (EHR) narratives. We present a…

Understanding a medical conversation between a patient and a physician poses a unique natural language understanding challenge since it combines elements of standard open ended conversation with very domain specific elements that require…

Computation and Language · Computer Science 2020-09-21 Anirudh Joshi , Namit Katariya , Xavier Amatriain , Anitha Kannan

Hospital discharge documentation is among the most essential, yet time-consuming documents written by medical practitioners. The objective of this study was to automatically generate hospital discharge summaries using neural network…

Computation and Language · Computer Science 2023-05-25 Koyena Pal , Seyed Ali Bahrainian , Laura Mercurio , Carsten Eickhoff

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

Machine Learning · Computer Science 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Background: More than half (57%) of pharma clinical research spend is in support of clinical trials. One reason is that Electronic Health Record (EHR) systems and HIPAA privacy rules often limit how broadly patient information can be…

Quantitative Methods · Quantitative Biology 2018-07-03 Andrew J McMurry , Richen Zhang , Alex Foxman , Lawrence Reiter , Ronny Schnel , DeLeys Brandman

Electronic health records (EHRs) and other real-world clinical data are essential for clinical research, medical artificial intelligence, and life science, but their sharing is severely limited by privacy, governance, and interoperability…

Cryptography and Security · Computer Science 2026-03-25 Maolin Wang , Beining Bao , Gan Yuan , Hongyu Chen , Bingkun Zhao , Baoshuo Kan , Jiming Xu , Qi Shi , Yinggong Zhao , Yao Wang , Wei Ying Ma , Jun Yan

In the past decade, with the development of big data technology, an increasing amount of patient information has been stored as electronic health records (EHRs). Leveraging these data, various doctor recommendation systems have been…

Information Retrieval · Computer Science 2022-07-14 Luning Bi , Yunlong Wang , Fan Zhang , Zhuqing Liu , Yong Cai , Emily Zhao

Applying methods in natural language processing on electronic health records (EHR) data is a growing field. Existing corpus and annotation focus on modeling textual features and relation prediction. However, there is a paucity of annotated…

Computation and Language · Computer Science 2022-04-08 Yanjun Gao , Dmitriy Dligach , Timothy Miller , Samuel Tesch , Ryan Laffin , Matthew M. Churpek , Majid Afshar

Electronic Health Records (EHRs) contain extensive patient information that can inform downstream clinical decisions, such as mortality prediction, disease phenotyping, and disease onset prediction. A key challenge in EHR data analysis is…

Applications · Statistics 2026-01-01 Xin Gai , Shiyi Jiang , Anru R. Zhang

The continuously increasing cost of the US healthcare system has received significant attention. Central to the ideas aimed at curbing this trend is the use of technology, in the form of the mandate to implement electronic health records…

Information Retrieval · Computer Science 2017-03-24 Pranjul Yadav , Michael Steinbach , Vipin Kumar , Gyorgy Simon

Background: Electronic health records (EHRs) enable machine learning for diagnosis, prognosis, and clinical decision support. However, EHR standards vary by country and hospital, making records often incompatible. This limits large-scale…

Information Retrieval · Computer Science 2026-03-27 Jiawei Zhao , Md Shamim Ahmed , Nicolai Dinh Khang Truong , Verena Schuster , Rudolf Mayer , Richard Röttger

Electronic health record (EHR) management systems require the adoption of effective technologies when health information is being exchanged. Current management approaches often face risks that may expose medical record storage solutions to…

Cryptography and Security · Computer Science 2021-01-28 Charalampos Stamatellis , Pavlos Papadopoulos , Nikolaos Pitropakis , Sokratis Katsikas , William J Buchanan

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu
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