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Reliable tools and software for penetrance (age-specific risk among those who carry a genetic variant) estimation are critical to improving clinical decision making and risk assessment for hereditary syndromes. We introduce penetrance, an…

Computation · Statistics 2025-03-28 Nicolas Kubista , Danielle Braun , Giovanni Parmigiani

The matrixdist R package provides a comprehensive suite of tools for the statistical analysis of matrix distributions, including phase-type, inhomogeneous phase-type, discrete phase-type, and related multivariate distributions. This paper…

Computation · Statistics 2025-03-11 Martin Bladt , Alaric Mueller , Jorge Yslas

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

We consider extension of Granger causality to nonlinear bivariate time series. In this frame, if the prediction error of the first time series is reduced by including measurements from the second time series, then the second time series is…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Nicola Ancona , Daniele Marinazzo , Sebastiano Stramaglia

varstan is an \proglang{R} package for Bayesian analysis of time series models using \proglang{Stan}. The package offers a dynamic way to choose a model, define priors in a wide range of distributions, check model's fit, and forecast with…

Computation · Statistics 2020-05-22 Izhar Asael Alonzo Matamoros , Cristian Andres Cruz Torres

Granger causality (GC) is undoubtedly the most widely used method to infer cause-effect relations from observational time series. Several nonlinear alternatives to GC have been proposed based on kernel methods. We generalize kernel Granger…

Chaotic Dynamics · Physics 2020-12-10 Diego Bueso , Maria Piles , Gustau Camps-Valls

We describe an R package developed by the research group Turbulence, Wind energy and Stochastics (TWiSt) at the Carl von Ossietzky University of Oldenburg, which extracts the (stochastic) evolution equation underlying a set of data or…

Data Analysis, Statistics and Probability · Physics 2016-08-30 Philip Rinn , Pedro G. Lind , Matthias Wächter , Joachim Peinke

This report reviews the conceptual and theoretical links between Granger causality and directed information theory. We begin with a short historical tour of Granger causality, concentrating on its closeness to information theory. The…

Information Theory · Computer Science 2015-06-12 Pierre-Olivier Amblard , Olivier J. J. Michel

Cross-slice attack attribution in 6G networks faces the fundamental challenge of distinguishing genuine causal relationships from spurious correlations in shared infrastructure environments. We propose a theoretically-grounded…

Cryptography and Security · Computer Science 2025-10-08 Minh K. Quan , Pubudu N. Pathirana

We provide methods for in-database support of decision making under uncertainty. Many important decision problems correspond to selecting a package (bag of tuples in a relational database) that jointly satisfy a set of constraints while…

Databases · Computer Science 2021-03-12 Matteo Brucato , Nishant Yadav , Azza Abouzied , Peter J. Haas , Alexandra Meliou

Wiener and Granger have introduced an intuitive concept of causality between two variables which is based on the idea that an effect never occurs before its cause. Later, Geweke has generalized this concept to a multivariate Granger…

Generating artificial data is a crucial step when performing Monte-Carlo simulation studies. Depending on the planned study, complex data generation processes (DGP) containing multiple, possibly time-varying, variables with various forms of…

Methodology · Statistics 2025-06-03 Robin Denz , Nina Timmesfeld

The longevity R package provides provide maximum likelihood estimation routine for modelling of survival data that are subject to non-informative censoring and truncation mechanisms. It includes a selection of 12 parametric models of…

Applications · Statistics 2023-11-17 Léo R. Belzile

Correlation among the observations in high-dimensional regression modeling can be a major source of confounding. We present a new open-source package, plmmr, to implement penalized linear mixed models in R. This R package estimates…

Computation · Statistics 2026-05-13 Tabitha K. Peter , Anna C. Reisetter , Yujing Lu , Oscar A. Rysavy , Patrick J. Breheny

Rgbp is an R package that provides estimates and verifiable confidence intervals for random effects in two-level conjugate hierarchical models for overdispersed Gaussian, Poisson, and Binomial data. Rgbp models aggregate data from k…

Methodology · Statistics 2017-10-23 Hyungsuk Tak , Joseph Kelly , Carl N. Morris

Longitudinal (panel) data provide the opportunity to examine temporal patterns of individuals, because measurements are collected on the same person at different, and often irregular, time points. The data is typically visualised using a…

Applications · Statistics 2020-12-04 Nicholas J Tierney , Dianne Cook , Tania Prvan

While most classical approaches to Granger causality detection assume linear dynamics, many interactions in real-world applications, like neuroscience and genomics, are inherently nonlinear. In these cases, using linear models may lead to…

Machine Learning · Statistics 2021-03-16 Alex Tank , Ian Covert , Nicholas Foti , Ali Shojaie , Emily Fox

An approach is proposed for inferring Granger causality between jointly stationary, Gaussian signals from quantized data. First, a necessary and sufficient rank criterion for the equality of two conditional Gaussian distributions is proved.…

Systems and Control · Electrical Eng. & Systems 2022-02-07 Salman Ahmadi , Girish N. Nair , Erik Weyer

We introduce the R package \CRANpkg{SIHR} for statistical inference in high-dimensional generalized linear models with continuous and binary outcomes. The package provides functionalities for constructing confidence intervals and performing…

Computation · Statistics 2023-05-03 Prabrisha Rakshit , Zhenyu Wang , T. Tony Cai , Zijian Guo

The sparse group lasso is a high-dimensional regression technique that is useful for problems whose predictors have a naturally grouped structure and where sparsity is encouraged at both the group and individual predictor level. In this…