Related papers: From Classification to Generation: An Open-Ended P…

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Retrieval-Augmented Generation (RAG) systems leverage Large Language Models (LLMs) to generate accurate and reliable responses that are grounded in retrieved context. However, LLMs often generate inconsistent outputs for semantically…

The capacity of Large Language Models (LLMs) to follow complex instructions and generate factually accurate text is critical for their real-world application. However, standard decoding methods often fail to robustly satisfy these…

Retrieval-augmented generation (RAG) is a paradigm that augments large language models (LLMs) with external knowledge to tackle knowledge-intensive question answering. While several benchmarks evaluate Multimodal LLMs (MLLMs) under…

Recent advances in deep learning have accelerated its use in various applications, such as cellular image analysis and molecular discovery. In molecular discovery, a generative adversarial network (GAN), which comprises a discriminator to…

Retrieval-Augmented Generation (RAG) systems enhance Large Language Models (LLMs) by retrieving relevant documents from external corpora before generating responses. This approach significantly expands LLM capabilities by leveraging vast,…

Retrieval-augmented generation (RAG) utilizes retrieved texts to enhance large language models (LLMs). Studies show that while RAG provides valuable external information (benefit), it may also mislead LLMs (detriment) with noisy or…

Graph-based Retrieval-Augmented Generation (GraphRAG) has become the important paradigm for enhancing Large Language Models (LLMs) with external knowledge. However, existing approaches are constrained by their reliance on high-quality…

Alzheimer's disease (AD) is a progressive neurodegenerative condition necessitating early and precise diagnosis to provide prompt clinical management. Given the paramount importance of early diagnosis, recent studies have increasingly…

Understanding mechanistic relationships among genes and their impacts on biological pathways is essential for elucidating disease mechanisms and advancing precision medicine. Despite the availability of extensive molecular interaction and…

Motivation: Mendelian randomization (MR) infers causal relationships between exposures and outcomes using genetic variants as instrumental variables. Typically, MR considers only a pair of exposure and outcome at a time, limiting its…

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Retrieval-Augmented Generation (RAG) enables large language models (LLMs) to access external knowledge sources, but the effectiveness of RAG relies on the coordination between the retriever and the generator. Since these components are…

Training generative models that capture rich semantics of the data and interpreting the latent representations encoded by such models are very important problems in un-/self-supervised learning. In this work, we provide a simple algorithm…

Graph generation techniques are increasingly being adopted for drug discovery. Previous graph generation approaches have utilized relatively small molecular building blocks such as atoms or simple cycles, limiting their effectiveness to…

The impressive performance of proprietary LLMs like GPT4 in code generation has led to a trend to replicate these capabilities in open-source models through knowledge distillation (e.g. Code Evol-Instruct). However, these efforts often…

The rapid progress in large language models (LLMs) has paved the way for novel approaches in knowledge-intensive tasks. Among these, Cache-Augmented Generation (CAG) has emerged as a promising alternative to Retrieval-Augmented Generation…

Drug-drug interactions are preventable causes of medical injuries and often result in doctor and emergency room visits. Computational techniques can be used to predict potential drug-drug interactions. We approach the drug-drug interaction…

Retrieval-Augmented Generation (RAG), by integrating non-parametric knowledge from external knowledge bases into models, has emerged as a promising approach to enhancing response accuracy while mitigating factual errors and hallucinations.…

Multi-modal multi-label emotion recognition (MMER) aims to identify relevant emotions from multiple modalities. The challenge of MMER is how to effectively capture discriminative features for multiple labels from heterogeneous data. Recent…