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The neocortex, a complex system driving multi-region interactions, remains a core puzzle in neuroscience. Despite quantitative insights across brain scales, understanding the mechanisms underlying neural activities is challenging. Advances…

Neurons and Cognition · Quantitative Biology 2024-11-27 Xiaochen Wang , Yuxuan Wu , Feng Zhang , Jin Wang

A model computational quantum thermodynamic network is constructed with two variable temperature baths coupled by a linker system, with an asymmetry in the coupling of the linker to the two baths. It is found in computational simulations…

Statistical Mechanics · Physics 2021-11-10 Phillip C. Lotshaw , Michael E. Kellman

Stochastic neural networks are a prototypical computational device able to build a probabilistic representation of an ensemble of external stimuli. Building on the relationship between inference and learning, we derive a synaptic plasticity…

Disordered Systems and Neural Networks · Physics 2018-10-23 Luca Saglietti , Federica Gerace , Alessandro Ingrosso , Carlo Baldassi , Riccardo Zecchina

Stochastic differential equations (SDEs) are of utmost importance in various scientific and industrial areas. They are the natural description of dynamical processes whose precise equations of motion are either not known or too expensive to…

Methodology · Statistics 2017-11-08 Philipp Frank , Theo Steininger , Torsten A. Enßlin

The question of characterization of the degree of non-equilibrium activity in active matter systems is studied in the context of a stochastic microswimmer model driven by a chemical cycle. The resulting dynamical properties and entropy…

Statistical Mechanics · Physics 2024-05-27 Michalis Chatzittofi , Jaime Agudo-Canalejo , Ramin Golestanian

The manifold hypothesis suggests that high-dimensional neural time series lie on a low-dimensional manifold shaped by simpler underlying dynamics. To uncover this structure, latent dynamical variable models such as state-space models,…

Machine Learning · Computer Science 2025-07-30 Pedram Rajaei , Maryam Ostadsharif Memar , Navid Ziaei , Behzad Nazari , Ali Yousefi

We present the design for a thermodynamic computer that can perform arbitrary nonlinear calculations in or out of equilibrium. Simple thermodynamic circuits, fluctuating degrees of freedom in contact with a thermal bath and confined by a…

Statistical Mechanics · Physics 2026-01-08 Stephen Whitelam , Corneel Casert

In these lecture notes, the basic principles of stochastic thermodynamics are developed starting with a closed system in contact with a heat bath. A trajectory undergoes Markovian transitions between observable meso-states that correspond…

Statistical Mechanics · Physics 2018-06-13 Udo Seifert

Thermodynamic computing exploits fluctuations and dissipation in physical systems to efficiently solve various mathematical problems. For example, it was recently shown that certain linear algebra problems can be solved thermodynamically,…

Statistical Mechanics · Physics 2024-01-08 Samuel Duffield , Maxwell Aifer , Gavin Crooks , Thomas Ahle , Patrick J. Coles

We provide a unified thermodynamic formalism describing information transfers in autonomous as well as nonautonomous systems described by stochastic thermodynamics. We demonstrate how information is continuously generated in an auxiliary…

Statistical Mechanics · Physics 2014-08-06 Jordan M. Horowitz , Massimiliano Esposito

Hydrodynamic theories effectively describe many-body systems out of equilibrium in terms of a few macroscopic parameters. However, such hydrodynamic parameters are difficult to derive from microscopics. Seldom is this challenge more…

Modern neuroscience has accumulated extensive evidence on perception, memory, prediction, valuation, and consciousness, yet still lacks an explicit operational architecture capable of integrating these phenomena within a unified…

Neurons and Cognition · Quantitative Biology 2026-03-17 Ionel Cristian Vladu , Nicu Bizdoaca , Ionica Pirici , Tudor-Adrian Balseanu , Eduard Nicusor Bondoc

In this work, we analyze the nonequilibrium thermodynamics of a class of neural networks known as Restricted Boltzmann Machines (RBMs) in the context of unsupervised learning. We show how the network is described as a discrete Markov…

Statistical Mechanics · Physics 2017-08-23 Domingos S. P. Salazar

We show that models of opinion formation and dissemination in a community of individuals can be framed within stochastic thermodynamics from which we can build a nonequilibrium thermodynamics of opinion dynamics. This is accomplished by…

Statistical Mechanics · Physics 2023-07-12 Tânia Tomé , Carlos E. Fiore , Mário J. de Oliveira

Autoregressive generative models -- including Transformers, recurrent neural networks, classical Kalman filters, state space models, and Mamba -- all generate sequences by sampling each output from a deterministic summary of the past,…

Statistical Mechanics · Physics 2026-04-17 Takahiro Sagawa

Fluctuations in parameters that are typically treated as fixed play a crucial role in the behavior of complex systems. However, to date, we lack a general non-equilibrium thermodynamic treatment of such a complex system. In this Letter, to…

Statistical Mechanics · Physics 2026-03-31 Tuan Pham , Deepak Gupta

We introduce a non-equilibrium density-functional theory of local temperature and associated local energy density that is suited for the study of thermoelectric phenomena. The theory rests on a local temperature field coupled to the…

Strongly Correlated Electrons · Physics 2014-05-16 F. G. Eich , M. Di Ventra , G. Vignale

We consider overdamped diffusion processes driven out of thermal equilibrium and we analyze their dynamical steady fluctuations. We discuss the thermodynamic interpretation of the joint fluctuations of occupation times and currents; they…

Statistical Mechanics · Physics 2009-11-13 Christian Maes , Karel Netocny , Bram Wynants

A core challenge in the interpretation of deep neural networks is identifying commonalities between the underlying algorithms implemented by distinct networks trained for the same task. Motivated by this problem, we introduce DYNAMO, an…

Machine Learning · Computer Science 2023-03-01 Jordan Cotler , Kai Sheng Tai , Felipe Hernández , Blake Elias , David Sussillo

Numerical annealing and renormalization group have conceived various successful approaches to study the thermodynamics of strongly-correlated systems where perturbation or expansion theories fail to work. As the process of lowering the…

Quantum Physics · Physics 2022-05-02 Ding-Zu Wang , Guo-Feng Zhang , Maciej Lewenstein , Shi-Ju Ran
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