Related papers: Nanodiamond-Enabled Torsion Microscopy Uncovers Mu…
Traction force microscopy is a method widely used in biophysics and cell biology to determine forces that biological cells apply to their environment. In the experiment, the cells adhere to a soft elastic substrate, which is then deformed…
Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chemical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we…
The electrical conductivity of a material can feature subtle, nontrivial, and spatially-varying signatures with critical insight into the material's underlying physics. Here we demonstrate a conductivity imaging technique based on the…
In order to give insights into how anisotropic nano-objects interact with living cell membranes, and possibly self-assemble, we designed magnetic nanorods with average size around 100 nm x 1$\mu$m by assembling iron oxide nanocubes within a…
The precise measurement of mechanical stress at the nanoscale is of fundamental and technological importance. In principle, all six independent variables of the stress tensor, which describe the direction and magnitude of…
Viscoelasticity of the cytoplasm plays a critical role in cell morphology and division. In parallel, local temperature is coupled to viscoelasticity and influences cellular bioenergetics. Probing the interdependence of intracellular…
The fluorescent nitrogen-vacancy (NV) defect in diamond has remarkable photophysical properties, including high photostability, which allows stable fluorescence emission for hours; as a result, there has been much interest in using…
Adherent biological cells generate traction forces on a substrate that play a central role for migration, mechanosensing, differentiation, and collective behavior. The established method for quantifying this cell-substrate interaction is…
Optical bio-markers have been used extensively for intracellular imaging with high spatial and temporal resolution. Extending the modality of these probes is a key driver in cell biology. In recent years, the NV centre in nanodiamond has…
The nitrogen-vacancy (NV) center in diamond exists in different charge states with distinct photoluminescence properties, which are sensitive to the nanoscale electrochemical environment. Hence, the NV charge state is emerging as a powerful…
Diffusion tensor imaging provides increased sensitivity to microstructural tissue changes compared to conventional anatomical imaging but also presents limited specificity. To tackle this problem, the DIAMOND model subdivides the voxel…
The confluence of quantum physics and biology is driving a new generation of quantum-based sensing and imaging technology capable of harnessing the power of quantum effects to provide tools to understand the fundamental processes of life.…
The local thermal conductivity (\k{appa}) is a pivotal biophysical parameter, governing intracellular heat flux and underlying functional processes like metabolic regulation and stress response. However, label-free mapping with sub-micron…
Owing to the unique electronic spin properties, the nitrogen-vacancy (NV) centers hosted in diamond have emerged as a powerful quantum sensor for various physical parameters and biological species. In this work, a miniature optical-fiber…
Magnetic sensing technology has found widespread application in industries as diverse as transportation, medicine, and resource exploration. Such use cases often require highly sensitive instruments to measure the extremely small magnetic…
This study presents a novel, versatile traction force microscopy framework for quantifying three-dimensional (3D) interfacial forces during bio-adhesion by integrating in situ stereo digital image correlation with finite element (FE)…
High biocompatibility, variable size ranging from ~ 5 nm, stable luminescence from its color centers and simple carbon chemistry for biomolecule grafting make nanodiamond (ND) particles an attractive alternative to molecular dyes for…
In this article we explore the requirements for enabling high quality optically detected magnetic resonance (ODMR) spectroscopy in a conventional gradient force optical tweezers using nanodiamonds containing nitrogen-vacancy (NV$^{-}$)…
Nanodiamond reinforced silver matrix nanocomposites with different nanodiamond content are produced from pure silver and nanodiamond powders by a combination of two severe plastic deformation methods, ball-milling and high-pressure torsion…
Deterministic optical manipulation of fluorescent nanodiamonds (FNDs) in fluids has emerged as an experimental challenge in multimodal biological imaging. Designing and developing nano-optical trapping strategies to serve this purpose is an…