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We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Musculoskeletal diseases such as sarcopenia and osteoporosis are major obstacles to health during aging. Although dual-energy X-ray absorptiometry (DXA) and computed tomography (CT) can be used to evaluate musculoskeletal conditions,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Yi Gu , Yoshito Otake , Keisuke Uemura , Masaki Takao , Mazen Soufi , Yuta Hiasa , Hugues Talbot , Seiji Okata , Nobuhiko Sugano , Yoshinobu Sato

Two-sample tests have been extensively employed in various scientific fields and machine learning such as evaluation on the effectiveness of drugs and A/B testing on different marketing strategies to discriminate whether two sets of samples…

Quantum Physics · Physics 2025-11-27 Yu Terada , Yugo Ogio , Ken Arai , Hiroyuki Tezuka , Yu Tanaka

This article presents a quantum computing approach to designing of similarity measures and kernels for classification of stochastic symbolic time series. In the area of machine learning, kernels are important components of various…

Quantum Physics · Physics 2025-06-10 Vanio Markov , Vladimir Rastunkov , Daniel Fry

Quantum-information-inspired experiments in nuclear magnetic resonance spectroscopy may yield a pathway towards determining molecular structure and properties that are otherwise challenging to learn. We measure out-of-time-ordered…

Quantum Physics · Physics 2025-10-23 C. Zhang , R. G. Cortiñas , A. H. Karamlou , N. Noll , J. Provazza , J. Bausch , S. Shirobokov , A. White , M. Claassen , S. H. Kang , A. W. Senior , N. Tomašev , J. Gross , K. Lee , T. Schuster , W. J. Huggins , H. Celik , A. Greene , B. Kozlovskii , F. J. H. Heras , A. Bengtsson , A. Grajales Dau , I. Drozdov , B. Ying , W. Livingstone , V. Sivak , N. Yosri , C. Quintana , D. Abanin , A. Abbas , R. Acharya , L. Aghababaie Beni , G. Aigeldinger , R. Alcaraz , S. Alcaraz , T. I. Andersen , M. Ansmann , F. Arute , K. Arya , W. Askew , N. Astrakhantsev , J. Atalaya , B. Ballard , J. C. Bardin , H. Bates , M. Bigdeli Karimi , A. Bilmes , S. Bilodeau , F. Borjans , A. Bourassa , J. Bovaird , D. Bowers , L. Brill , P. Brooks , M. Broughton , D. A. Browne , B. Buchea , B. B. Buckley , T. Burger , B. Burkett , J. Busnaina , N. Bushnell , A. Cabrera , J. Campero , H. -S. Chang , S. Chen , Z. Chen , B. Chiaro , L. -Y. Chih , A. Y. Cleland , B. Cochrane , M. Cockrell , J. Cogan , R. Collins , P. Conner , H. Cook , W. Courtney , A. L. Crook , B. Curtin , S. Das , M. Damyanov , D. M. Debroy , L. De Lorenzo , S. Demura , L. B. De Rose , A. Di Paolo , P. Donohoe , A. Dunsworth , V. Ehimhen , A. Eickbusch , A. M. Elbag , L. Ella , M. Elzouka , D. Enriquez , C. Erickson , V. S. Ferreira , M. Flores , L. Flores Burgos , E. Forati , J. Ford , A. G. Fowler , B. Foxen , M. Fukami , A. W. L. Fung , L. Fuste , S. Ganjam , G. Garcia , C. Garrick , R. Gasca , H. Gehring , R. Geiger , É. Genois , W. Giang , C. Gidney , D. Gilboa , J. E. Goeders , E. C. Gonzales , R. Gosula , S. J. de Graaf , D. Graumann , J. Grebel , J. Guerrero , J. D. Guimarães , T. Ha , S. Habegger , T. Hadick , A. Hadjikhani , M. P. Harrigan , S. D. Harrington , J. Hartshorn , S. Heslin , P. Heu , O. Higgott , R. Hiltermann , J. Hilton , H. -Y. Huang , M. Hucka , C. Hudspeth , A. Huff , E. Jeffrey , S. Jevons , Z. Jiang , X. Jin , C. Joshi , P. Juhas , A. Kabel , H. Kang , K. Kang , R. Kaufman , K. Kechedzhi , T. Khattar , M. Khezri , S. Kim , R. King , O. Kiss , P. V. Klimov , C. M. Knaut , B. Kobrin , F. Kostritsa , J. M. Kreikebaum , R. Kudo , B. Kueffler , A. Kumar , V. D. Kurilovich , V. Kutsko , N. Lacroix , D. Landhuis , T. Lange-Dei , B. W. Langley , P. Laptev , K. -M. Lau , L. Le Guevel , J. Ledford , J. Lee , B. J. Lester , W. Leung , L. Li , W. Y. Li , M. Li , A. T. Lill , M. T. Lloyd , A. Locharla , D. Lundahl , A. Lunt , S. Madhuk , A. Maiti , A. Maloney , S. Mandra , L. S. Martin , O. Martin , E. Mascot , P. Masih Das , D. Maslov , M. Mathews , C. Maxfield , J. R. McClean , M. McEwen , S. Meeks , K. C. Miao , R. Molavi , S. Molina , S. Montazeri , C. Neill , M. Newman , A. Nguyen , M. Nguyen , C. -H. Ni , M. Y. Niu , L. Oas , R. Orosco , K. Ottosson , A. Pagano , S. Peek , D. Peterson , A. Pizzuto , E. Portoles , R. Potter , O. Pritchard , M. Qian , A. Ranadive , M. J. Reagor , R. Resnick , D. M. Rhodes , D. Riley , G. Roberts , R. Rodriguez , E. Ropes , E. Rosenberg , E. Rosenfeld , D. Rosenstock , E. Rossi , D. A. Rower , M. S. Rudolph , R. Salazar , K. Sankaragomathi , M. C. Sarihan , K. J. Satzinger , M. Schaefer , S. Schroeder , H. F. Schurkus , A. Shahingohar , M. J. Shearn , A. Shorter , N. Shutty , V. Shvarts , S. Small , W. C. Smith , D. A. Sobel , R. D. Somma , B. Spells , S. Springer , G. Sterling , J. Suchard , A. Szasz , A. Sztein , M. Taylor , J. P. Thiruraman , D. Thor , D. Timucin , E. Tomita , A. Torres , M. M. Torunbalci , H. Tran , A. Vaishnav , J. Vargas , S. Vdovichev , G. Vidal , C. Vollgraff Heidweiller , M. Voorhees , S. Waltman , J. Waltz , S. X. Wang , B. Ware , J. D. Watson , Y. Wei , T. Weidel , T. White , K. Wong , B. W. K. Woo , C. J. Wood , M. Woodson , C. Xing , Z. J. Yao , P. Yeh , J. Yoo , E. Young , G. Young , A. Zalcman , R. Zhang , Y. Zhang , N. Zhu , N. Zobrist , Z. Zou , G. Bortoli , S. Boixo , J. Chen , Y. Chen , M. Devoret , M. Hansen , C. Jones , J. Kelly , P. Kohli , A. Korotkov , E. Lucero , J. Manyika , Y. Matias , A. Megrant , H. Neven , W. D. Oliver , G. Ramachandran , R. Babbush , V. Smelyanskiy , P. Roushan , D. Kafri , R. Sarpong , D. W. Berry , C. Ramanathan , X. Mi , C. Bengs , A. Ajoy , Z. K. Minev , N. C. Rubin , T. E. O'Brien

Computational biomarkers (CBs) are histopathology-derived patterns extracted from hematoxylin-eosin (H&E) whole-slide images (WSIs) using artificial intelligence (AI) to predict therapeutic response or prognosis. Recently, slide-level…

Background: In this second part of a two-part paper, we intend to demonstrate the impact of the previously proposed advanced quality control pipeline. To understand its benefit and challenge the proposed methodology in a real scenario, we…

These notes provide a self-contained introduction to kernel methods and their geometric foundations in machine learning. Starting from the construction of Hilbert spaces, we develop the theory of positive definite kernels, reproducing…

Quantitative Susceptibility Mapping (QSM) can estimate the underlying tissue magnetic susceptibility and reveal pathology. Current deep-learning-based approaches to solve the QSM inverse problem are restricted on fixed image resolution.…

Medical Physics · Physics 2019-08-02 Juan Liu , Kevin M. Koch

Chronic obstructive pulmonary disease (COPD) is a lung disease which can be quantified using chest computed tomography (CT) scans. Recent studies have shown that COPD can be automatically diagnosed using weakly supervised learning of…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Veronika Cheplygina , Isabel Pino Peña , Jesper Holst Pedersen , David A. Lynch , Lauge Sørensen , Marleen de Bruijne

Accurate prediction of protein active-site structures remains a central challenge in structural biology, particularly for short and flexible peptide fragments where conventional and simulation-based methods often fail. Here, we present a…

We consider the problem of distinguishing two vectors (visualized as images or barcodes) and learning if they are related to one another. For this, we develop a geometric quantum machine learning (GQML) approach with embedded symmetries…

Quantum Physics · Physics 2024-09-04 Chukwudubem Umeano , Stefano Scali , Oleksandr Kyriienko

We present a comprehensive study of the commute time kernel method via the effective resistance framework analyzing the quantum complexity of the originally classical approach. Our study reveals that while there is a trade-off between…

Quantum Physics · Physics 2026-01-06 Adam Wesołowski , Karim Essafi

Generalized Bayesian Inference (GBI) provides a flexible framework for updating prior distributions using various loss functions instead of the traditional likelihoods, thereby enhancing the model robustness to model misspecification.…

Machine Learning · Computer Science 2026-01-08 Elham Afzali , Saman Muthukumarana , Liqun Wang

Motivated by the challenging segmentation task of pancreatic tubular networks, this paper tackles two commonly encountered problems in biomedical imaging: Topological consistency of the segmentation, and expensive or difficult annotation.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-29 Kasra Arnavaz , Oswin Krause , Kilian Zepf , Jelena M. Krivokapic , Silja Heilmann , Jakob Andreas Bærentzen , Pia Nyeng , Aasa Feragen

Monitoring maternal and fetal health during pregnancy is crucial for preventing adverse outcomes. While tests such as ultrasound scans offer high accuracy, they can be costly and inconvenient. Telehealth and more accessible body shape…

Longitudinal biomedical studies monitor individuals over time to capture dynamics in brain development, disease progression, and treatment effects. However, estimating trajectories of brain biomarkers is challenging due to biological…

Machine Learning · Computer Science 2025-04-15 Vasiliki Tassopoulou , Haochang Shou , Christos Davatzikos

Kernel methods are an important class of techniques in machine learning. To be effective, good feature maps are crucial for mapping non-linearly separable input data into a higher dimensional (feature) space, thus allowing the data to be…

Quantum Physics · Physics 2024-07-16 Rowan Pellow-Jarman , Anban Pillay , Ilya Sinayskiy , Francesco Petruccione

As quantum computers become increasingly practical, so does the prospect of using quantum computation to improve upon traditional algorithms. Kernel methods in machine learning is one area where such improvements could be realized in the…

Quantum Physics · Physics 2023-05-30 Ara Ghukasyan , Jack S. Baker , Oktay Goktas , Juan Carrasquilla , Santosh Kumar Radha

This paper introduces an approach for detecting differences in the first-order structures of spatial point patterns. The proposed approach leverages the kernel mean embedding in a novel way by introducing its approximate version tailored to…

Methodology · Statistics 2020-06-15 Raif M. Rustamov , James T. Klosowski