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An electrocatalyst is needed to efficiently lower the reaction barriers to produce hydrogen through the H2 evolution reaction (HER). Recently, two-dimensional transition metal dichalcogenides (2D TMDs), such as the pure 2D monolayer MoTe2…

Materials Science · Physics 2024-04-24 Vikash Kumar , Srimanta Pakhira

Bacterial contamination of biological conducts, catheters or water resources is a major threat to public health and can be amplified by the ability of bacteria to swim upstream. The mechanisms of this rheotaxis, the reorientation with…

Soft Condensed Matter · Physics 2019-08-12 Arnold Mathijssen , Nuris Figueroa-Morales , Gaspard Junot , Eric Clement , Anke Lindner , Andreas Zöttl

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

Biological Physics · Physics 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

The multidrug resistant Escherichia coli strains causes multiple clinical infections and has become a rising problem globally. The metallo-\b{eta}-lactamases encoding genes are very severe in gram-negative bacteria especially E. coli. This…

Other Quantitative Biology · Quantitative Biology 2019-04-11 Fazlul MKK , Deepthi S , Farzana Y , Najnin A , Rashid Ma , Munira B , Srikumar C , Nazmul

Sulfide solid state electrolytes are promising candidates to realize all solid state batteries due to their superior ionic conductivity and excellent ductility. However, their hypersensitivity to moisture requires processing environments…

The ability to monitor nutrient and other environmental conditions with high sensitivity is crucial for cell growth and survival. Sensory adaptation allows a cell to recover its sensitivity after a transient response to a shift in the…

Subcellular Processes · Quantitative Biology 2016-01-07 Shou-Wen Wang , Yueheng Lan , Lei-Han Tang

This paper presents a new vision Transformer, Scale-Aware Modulation Transformer (SMT), that can handle various downstream tasks efficiently by combining the convolutional network and vision Transformer. The proposed Scale-Aware Modulation…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Weifeng Lin , Ziheng Wu , Jiayu Chen , Jun Huang , Lianwen Jin

In many sensory systems, transmembrane receptors are spatially organized in large clusters. Such arrangement may facilitate signal amplification and the integration of multiple stimuli. However, this organization likely also affects the…

Molecular Networks · Quantitative Biology 2014-03-05 William Pontius , Michael W. Sneddon , Thierry Emonet

Structural transformations in molecules and solids have generally been studied in isolation, while intermediate systems have eluded characterization. We show that a pair of CdS cluster isomers provides an advantageous experimental platform…

Non-native conformations drive protein misfolding diseases, complicate bioengineering efforts, and fuel molecular evolution. No current experimental technique is well-suited for elucidating them and their phenotypic effects. Especially…

Understanding why some cellular components are conserved across species, while others evolve rapidly is a key question of modern biology. Here we demonstrate that in S. cerevisiae proteins organized in cohesive patterns of interactions are…

Genomics · Quantitative Biology 2007-05-23 S. Wuchty , Z. N. Oltvai , A. -L. Barabasi

The effect of sequence heterogeneity on polynucleotide translocation across a pore and on simple models of molecular motors such as helicases, DNA polymerase/exonuclease and RNA polymerase is studied in detail. Pore translocation of RNA or…

Statistical Mechanics · Physics 2009-11-10 Yariv Kafri , David K. Lubensky , David R. Nelson

Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which…

Molecular Networks · Quantitative Biology 2015-06-05 Rogier Braakman , Eric Smith

Cellular contractility, migration, and extracellular matrix (ECM) mechanics are critical for a wide range of biological processes including embryonic development, wound healing, tissue morphogenesis, and regeneration. Even though the…

Biological Physics · Physics 2023-10-17 Jaemin Kim , Mahmut Selman Sakar , Nikolaos Bouklas

Respiration in bacteria involves a sequence of energetically-coupled electron and proton transfers creating an electrochemical gradient of protons (a proton-motive force) across the inner bacterial membrane. With a simple kinetic model we…

Biological Physics · Physics 2015-05-13 Anatoly Yu. Smirnov , Sergey E. Savel'ev , Franco Nori

Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often combine epithelial and mesenchymal features and tend to…

Cell Behavior · Quantitative Biology 2019-04-17 Dongya Jia , Xuefei Li , Federico Bocci , Shubham Tripathi , Youyuan Deng , Mohit Kumar Jolly , Jose N. Onuchic , Herbert Levine

Hybrid oxide molecular beam epitaxy (hMBE), a thin-film deposition technique in which transition metal cations are delivered using a metal-organic precursor, has emerged as the state-of-the-art approach to the synthesis of electronic-grade…

Bacterial chemotaxis in Escherichia coli is a canonical system for the study of signal transduction. A remarkable feature of this system is the coexistence of precise adaptation in population with large fluctuating cellular behavior in…

Molecular Networks · Quantitative Biology 2019-08-19 Thierry Emonet , Philippe Cluzel

Antimonene is a novel two-dimensional topological semiconductor material with strain driven tunable electronic structure for future electronic and spintronic devices, but the growth of clean antimonene is not fully understood. In this work,…

Materials Science · Physics 2021-12-15 Kai Liu , Keke Bai , Jing Wang , Juntao Song , Ying Liu

Cellular adaptation to environmental changes relies on the dynamic remodeling of subcellular structures. Among these, sarcomere structures are fundamental to the organization and function of the cytoskeletal architecture. In muscle-type…

Cell Behavior · Quantitative Biology 2024-12-17 Yuika Ueda , Shinji Deguchi
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