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Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

In this study, we aim to initiate the development of Radiology Foundation Model, termed as RadFM. We consider the construction of foundational models from three perspectives, namely, dataset construction, model design, and thorough…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Chaoyi Wu , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

There is substantial interest in developing artificial intelligence systems to support radiologists across tasks ranging from segmentation to report generation. Existing computed tomography (CT) foundation models have largely focused on…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Rubén Moreno-Aguado , Alba Magallón , Victor Moreno , Yingying Fang , Guang Yang

Vision-language models trained with contrastive learning on paired medical images and reports show strong zero-shot diagnostic capabilities, yet the effect of training batch composition on learned representations remains unexplored for 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Shivika , Kartik Bose , Pankaj Gupta

Foundation models such as Segment Anything Model 2 (SAM 2) exhibit strong generalization on natural images and videos but perform poorly on medical data due to differences in appearance statistics, imaging physics, and three-dimensional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Satrajit Chakrabarty , Sourya Sengupta , Gopal Avinash , Ravi Soni

Segmenting 3D blood vessels is a critical yet challenging task in medical image analysis. This is due to significant imaging modality-specific variations in artifacts, vascular patterns and scales, signal-to-noise ratios, and background…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Bastian Wittmann , Yannick Wattenberg , Tamaz Amiranashvili , Suprosanna Shit , Bjoern Menze

General-purpose vision-language models (VLMs) have emerged as promising tools in radiology, offering zero-shot capabilities that mitigate the need for large labeled datasets. However, in high-stakes domains like diagnostic radiology, these…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Hao-Chih Lee , Zelong Liu , Hamza Ahmed , Spencer Kim , Sean Huver , Vishwesh Nath , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Pretraining with large-scale 3D volumes has a potential for improving the segmentation performance on a target medical image dataset where the training images and annotations are limited. Due to the high cost of acquiring pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Guotai Wang , Jianghao Wu , Xiangde Luo , Xinglong Liu , Kang Li , Shaoting Zhang

Foundation models like the Segment Anything Model (SAM) excel in zero-shot segmentation for natural images but struggle with medical image segmentation due to differences in texture, contrast, and noise. Annotating medical images is costly…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Sourya Sengupta , Satrajit Chakrabarty , Keerthi Sravan Ravi , Gopal Avinash , Ravi Soni

Reliable identification of anatomical body regions is a prerequisite for many automated medical imaging workflows, yet existing solutions remain heavily dependent on unreliable DICOM metadata. Current solutions mainly use supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Farnaz Khun Jush , Grit Werner , Mark Klemens , Matthias Lenga

3D medical vision-language (VL) pretraining has shown potential in radiology by leveraging large-scale multimodal datasets with CT-report pairs. However, existing methods primarily rely on a global VL alignment directly adapted from 2D…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Jingyang Lin , Yingda Xia , Jianpeng Zhang , Ke Yan , Kai Cao , Le Lu , Jiebo Luo , Ling Zhang

The advancement of artificial intelligence (AI) for organ segmentation and tumor detection is propelled by the growing availability of computed tomography (CT) datasets with detailed, per-voxel annotations. However, these AI models often…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Jie Liu , Yixiao Zhang , Kang Wang , Mehmet Can Yavuz , Xiaoxi Chen , Yixuan Yuan , Haoliang Li , Yang Yang , Alan Yuille , Yucheng Tang , Zongwei Zhou

Segmentation of multiple organs-at-risk (OARs) is essential for radiation therapy treatment planning and other clinical applications. We developed an Automated deep Learning-based Abdominal Multi-Organ segmentation (ALAMO) framework based…

Image and Video Processing · Electrical Eng. & Systems 2020-08-25 Yuhua Chen , Dan Ruan , Jiayu Xiao , Lixia Wang , Bin Sun , Rola Saouaf , Wensha Yang , Debiao Li , Zhaoyang Fan

Federated learning (FL) has become a promising paradigm for collaborative medical image analysis, yet existing frameworks remain tightly coupled to task-specific backbones and are fragile under heterogeneous imaging modalities. Such…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Meilin Liu , Jiaying Wang , Jing Shan

Recent advancements in foundation models have shown significant potential in medical image analysis. However, there is still a gap in models specifically designed for medical image localization. To address this, we introduce MedLAM, a 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Wenhui Lei , Xu Wei , Xiaofan Zhang , Kang Li , Shaoting Zhang

Automatic radiology report generation holds significant potential to streamline the labor-intensive process of report writing by radiologists, particularly for 3D radiographs such as CT scans. While CT scans are critical for clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Che Liu , Zhongwei Wan , Yuqi Wang , Hui Shen , Haozhe Wang , Kangyu Zheng , Mi Zhang , Rossella Arcucci

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain MRI alone. Human aging and disease arise through coordinated biological processes across…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Qiangqiang Wu , Grace McIlvain , Zhou Yu , Junhao Wen

Whole abdominal organ segmentation is important in diagnosing abdomen lesions, radiotherapy, and follow-up. However, oncologists' delineating all abdominal organs from 3D volumes is time-consuming and very expensive. Deep learning-based…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Xiangde Luo , Wenjun Liao , Jianghong Xiao , Jieneng Chen , Tao Song , Xiaofan Zhang , Kang Li , Dimitris N. Metaxas , Guotai Wang , Shaoting Zhang

While emerging 3D medical foundation models are envisioned as versatile tools with offer general-purpose capabilities, their validation remains largely confined to regional and structural imaging, leaving a significant modality discrepancy…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Yichi Zhang , Feiyang Xiao , Le Xue , Wenbo Zhang , Gang Feng , Chenguang Zheng , Yuan Qi , Yuan Cheng , Zixin Hu
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