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User and item attributes are essential side-information; their interactions (i.e., their co-occurrence in the sample data) can significantly enhance prediction accuracy in various recommender systems. We identify two different types of…

Information Retrieval · Computer Science 2021-07-26 Yixin Su , Rui Zhang , Sarah Erfani , Junhao Gan

A daunting challenge faced by modern biological sciences is finding an efficient and computationally feasible approach to deal with the curse of high dimensionality. The problem becomes even more severe when the research focus is on…

Methodology · Statistics 2013-04-16 Hung Hung , Yu-Tin Lin , Pengwen Chen , Chen-Chien Wang , Su-Yun Huang , Jung-Ying Tzeng

Interacting systems are ubiquitous in nature and engineering, ranging from particle dynamics in physics to functionally connected brain regions. These interacting systems can be modeled by graphs where edges correspond to the interactions…

Machine Learning · Computer Science 2024-01-25 Zhichao Han , Olga Fink , David S. Kammer

Interactions between pieces of information (entities) play a substantial role in the way an individual acts on them: adoption of a product, the spread of news, strategy choice, etc. However, the underlying interaction mechanisms are often…

Machine Learning · Computer Science 2022-02-02 Gaël Poux-Médard , Julien Velcin , Sabine Loudcher

Motivation. Association studies have been widely used to search for associations between common genetic variants observations and a given phenotype. However, it is now generally accepted that genes and environment must be examined jointly…

The remarkable progress of network embedding has led to state-of-the-art algorithms in recommendation. However, the sparsity of user-item interactions (i.e., explicit preferences) on websites remains a big challenge for predicting users'…

Information Retrieval · Computer Science 2019-07-30 Jun Zhao , Zhou Zhou , Ziyu Guan , Wei Zhao , Wei Ning , Guang Qiu , Xiaofei He

Recommender system research has oftentimes focused on approaches that operate on large-scale datasets containing millions of user interactions. However, many small businesses struggle to apply state-of-the-art models due to their very…

The prediction modeling of drug-target interactions is crucial to drug discovery and design, which has seen rapid advancements owing to deep learning technologies. Recently developed methods, such as those based on graph neural networks…

Quantitative Methods · Quantitative Biology 2025-11-19 Xinnan Zhang , Jialin Wu , Junyi Xie , Tianlong Chen , Kaixiong Zhou

Feature interactions are essential for achieving high accuracy in recommender systems. Many studies take into account the interaction between every pair of features. However, this is suboptimal because some feature interactions may not be…

Machine Learning · Computer Science 2021-05-19 Yixin Su , Rui Zhang , Sarah Erfani , Zhenghua Xu

Inspired by the immense success of deep learning, graph neural networks (GNNs) are widely used to learn powerful node representations and have demonstrated promising performance on different graph learning tasks. However, most real-world…

Machine Learning · Computer Science 2020-01-24 Kaize Ding , Yichuan Li , Jundong Li , Chenghao Liu , Huan Liu

Feature selection can efficiently identify the most informative features with respect to the target feature used in training. However, state-of-the-art vector-based methods are unable to encapsulate the relationships between feature samples…

Machine Learning · Computer Science 2018-09-11 Lixin Cui , Lu Bai , Zhihong Zhang , Yue Wang , Edwin R. Hancock

Adopting advances in recommendation systems is often challenging in industrial settings due to unique constraints. This paper aims to highlight these constraints through the lens of feature interactions. Feature interactions are critical…

Information Retrieval · Computer Science 2024-12-04 Siddarth Malreddy , Matthew Lawhon , Usha Amrutha Nookala , Aditya Mantha , Dhruvil Deven Badani

In domains where transparency and trustworthiness are crucial, such as healthcare, rule-based systems are widely used and often preferred over black-box models for decision support systems due to their inherent interpretability. However, as…

Machine Learning · Computer Science 2025-06-18 Christel Sirocchi , Damiano Verda

Much of the natural variation for a complex trait can be explained by variation in DNA sequence levels. As part of sequence variation, gene-gene interaction has been ubiquitously observed in nature, where its role in shaping the development…

Applications · Statistics 2012-10-01 Shaoyu Li , Yuehua Cui

Factorization machines (FM) are a popular model class to learn pairwise interactions by a low-rank approximation. Different from existing FM-based approaches which use a fixed rank for all features, this paper proposes a Rank-Aware FM…

Machine Learning · Computer Science 2019-05-21 Xiaoshuang Chen , Yin Zheng , Jiaxing Wang , Wenye Ma , Junzhou Huang

Graph neural networks (GNNs) are powerful tools for handling graph-structured data. However, their design often limits them to learning only higher-order feature interactions, leaving low-order feature interactions overlooked. To address…

Machine Learning · Computer Science 2024-06-14 Minkyu Kim , Hyun-Soo Choi , Jinho Kim

Factorization machine (FM) is a prevalent approach to modeling pairwise (second-order) feature interactions when dealing with high-dimensional sparse data. However, on the one hand, FM fails to capture higher-order feature interactions…

Machine Learning · Computer Science 2025-02-24 Shu Wu , Zekun Li , Yunyue Su , Zeyu Cui , Xiaoyu Zhang , Liang Wang

We propose a filtering feature selection framework that considers subsets of features as paths in a graph, where a node is a feature and an edge indicates pairwise (customizable) relations among features, dealing with relevance and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-16 Giorgio Roffo , Simone Melzi , Umberto Castellani , Alessandro Vinciarelli , Marco Cristani

One component of precision medicine is to construct prediction models with their predictive ability as high as possible, e.g. to enable individual risk prediction. In genetic epidemiology, complex diseases have a polygenic basis and a…

Machine Learning · Statistics 2019-01-28 Damian Gola , Inke R. König

Increasing evidence has shown that gene-gene interactions have important effects on biological processes of human diseases. Due to the high dimensionality of genetic measurements, existing interaction analysis methods usually suffer from a…

Methodology · Statistics 2021-01-11 Xing Qin , Shuangge Ma , Mengyun Wu
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