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Image reconstruction for positron emission tomography (PET) is challenging because of the ill-conditioned tomographic problem and low counting statistics. Kernel methods address this challenge by using kernel representation to incorporate…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Siqi Li , Guobao Wang

Dynamic positron emission tomography (PET) images can reveal the distribution of tracers in the organism and the dynamic processes involved in biochemical reactions, and it is widely used in clinical practice. Despite the high effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Jie Sun , Junyan Zhang , Qian Xia , Chuanfu Sun , Yumei Chen , Yunjie Yang , Huafeng Liu , Wentao Zhu , Qiegen Liu

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Direct reconstruction methods have been developed to estimate parametric images directly from the measured PET sinograms by combining the PET imaging model and tracer kinetics in an integrated framework. Due to limited counts received,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-22 Kuang Gong , Ciprian Catana , Jinyi Qi , Quanzheng Li

Image reconstruction of low-count positron emission tomography (PET) data is challenging. Kernel methods address the challenge by incorporating image prior information in the forward model of iterative PET image reconstruction. The…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Siqi Li , Kuang Gong , Ramsey D. Badawi , Edward J. Kim , Jinyi Qi , Guobao Wang

Low-dose positron emission tomography (PET) image reconstruction methods have potential to significantly improve PET as an imaging modality. Deep learning provides a promising means of incorporating prior information into the image…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Cameron Dennis Pain , Yasmeen George , Alex Fornito , Gary Egan , Zhaolin Chen

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

The kernel reconstruction is a method that reduces noise in dynamic positron emission tomography (PET) by exploiting spatial correlations in the PET image. Although this method works well for large anatomical regions with relatively slow…

Medical Physics · Physics 2025-07-31 Alan Miranda , Steven Staelens

Positron emission tomography (PET) is an important functional medical imaging technique often used in the evaluation of certain brain disorders, whose reconstruction problem is ill-posed. The vast majority of reconstruction methods in PET…

Image and Video Processing · Electrical Eng. & Systems 2023-06-09 Tin Vlašić , Tomislav Matulić , Damir Seršić

Achieving high image quality for temporal frames in dynamic positron emission tomography (PET) is challenging due to the limited statistic especially for the short frames. Recent studies have shown that deep learning (DL) is useful in a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Kuang Xiaodong , Li Bingxuan , Li Yuan , Rao Fan , Ma Gege , Xie Qingguo , Mok Greta S P , Liu Huafeng , Zhu Wentao

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

Purpose: Inversion recovery prepared ultra-short echo time (IR-UTE)-based MRI enables radiation-free visualization of osseous tissue. However, sufficient signal-to-noise ratio (SNR) can only be obtained with long acquisition times. This…

Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…

Computer Vision and Pattern Recognition · Computer Science 2019-06-12 Dufan Wu , Kyungsang Kim , Quanzheng Li

Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…

Medical Physics · Physics 2023-08-08 Fumio Hashimoto , Yuya Onishi , Kibo Ote , Hideaki Tashima , Taiga Yamaya

In the context of dynamic emission tomography, the conventional processing pipeline consists of independent image reconstruction of single time frames, followed by the application of a suitable kinetic model to time activity curves (TACs)…

Applications · Statistics 2018-08-28 Michele Scipioni , Stefano Pedemonte , Maria Filomena Santarelli , Luigi Landini

Dynamic positron emission tomography (dPET) is currently a widely used medical imaging technique for the clinical diagnosis, staging and therapy guidance of all kinds of human cancers. Higher temporal imaging resolution for the early stage…

Medical Physics · Physics 2021-12-07 Zixiang Chen , Yaping Wu , Na Zhang , Yu Shen , Hairong Zheng , Dong Liang , Meiyun Wang , Zhanli Hu

PET image reconstruction is challenging due to the ill-poseness of the inverse problem and limited number of detected photons. Recently deep neural networks have been widely and successfully used in computer vision tasks and attracted…

Computer Vision and Pattern Recognition · Computer Science 2017-10-11 Kuang Gong , Jiahui Guan , Kyungsang Kim , Xuezhu Zhang , Georges El Fakhri , Jinyi Qi , Quanzheng Li

Positron Emission Tomography (PET) is an essential technique in many clinical applications that allows for quantitative imaging at the molecular level. This study aims to develop a denoising method using novel dilated convolutional neural…

Medical Physics · Physics 2021-01-27 Karl Spuhler , Mario Serrano-Sosa , Renee Cattell , Christine DeLorenzo , Chuan Huang

Image denoising is a fundamental challenge in computer vision, with applications in photography and medical imaging. While deep learning-based methods have shown remarkable success, their reliance on specific noise distributions limits…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Dongjin Kim , Jaekyun Ko , Muhammad Kashif Ali , Tae Hyun Kim
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