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Accurate targeting is critical for the effectiveness of transcranial focused ultrasound (tFUS) neuromodulation. While CT provides accurate skull acoustic properties, its ionizing radiation and poor soft tissue contrast limit clinical…

Medical Physics · Physics 2025-07-14 Hengyu Gao , Shaodong Ding , Ziyang Liu , Jiefu Zhang , Bolun Li , Zhiwu An , Li Wang , Jing Jing , Tao Liu , Yubo Fan , Zhongtao Hu

Background: Individual skull models of bone density and geometry are important when planning the expected transcranial ultrasound acoustic field and estimating mechanical and thermal safety in low-intensity transcranial ultrasound…

Transcranial focused ultrasound (tFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively and often under MRI guidance. CT imaging is used to estimate the acoustic properties that vary…

Image and Video Processing · Electrical Eng. & Systems 2022-10-27 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Benoit M. Dawant , Charles F. Caskey

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Cortical surface reconstruction (CSR) from MRI is key to investigating brain structure and function. While recent deep learning approaches have significantly improved the speed of CSR, a substantial amount of runtime is still needed to map…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Xiaoyang Chen , Junjie Zhao , Siyuan Liu , Sahar Ahmad , Pew-Thian Yap

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

Brain segmentation from neonatal MRI images is a very challenging task due to large changes in the shape of cerebral structures and variations in signal intensities reflecting the gestational process. In this context, there is a clear need…

Machine Learning · Statistics 2023-09-12 R Valabregue , F Girka , A Pron , F Rousseau , G Auzias

MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Transcranial MRI-guided focused ultrasound (TcMRgFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively under MRI guidance. It is clinically approved to thermally ablate regions of the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Charles F. Caskey , Benoit M. Dawant

The generation of synthetic CT (sCT) images from cone-beam CT (CBCT) data using deep learning methodologies represents a significant advancement in radiation oncology. This systematic review, following PRISMA guidelines and using the PICO…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Alzahra Altalib , Scott McGregor , Chunhui Li , Alessandro Perelli

This paper presents an annotated dataset of brain MRI images designed to advance the field of brain symmetry study. Magnetic resonance imaging (MRI) has gained interest in analyzing brain symmetry in neonatal infants, and challenges remain…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Arnaud Gucciardi , Safouane El Ghazouali , Francesca Venturini , Vida Groznik , Umberto Michelucci

Accurate synthesis of computed tomography (CT) images from magnetic resonance imaging (MRI) is clinically valuable for cranial applications such as attenuation correction, radiotherapy planning, and image-guided interventions. However,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Zhuoyao Xin , Yiren Zhang , Christopher Wu , Dong Liu , Chunming Gu , Elena Greco , Erik H. Middlebrooks , Jun Hua , Jia Guo

Skullstripping is defined as the task of segmenting brain tissue from a full head magnetic resonance image~(MRI). It is a critical component in neuroimage processing pipelines. Downstream deformable registration and whole brain segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-04-30 Amod Jog , P. Ellen Grant , Joseph L. Jacobson , Andre van der Kouwe , Ernesta M. Meintjes , Bruce Fischl , Lilla Zöllei

Extracranial tissues visible on brain magnetic resonance imaging (MRI) may hold significant value for characterizing health conditions and clinical decision-making, yet they are rarely quantified. Current tools have not been widely…

Computed tomography (CT) is a widely used imaging modality for medical diagnosis and treatment. In electroencephalography (EEG), CT imaging is necessary for co-registering with magnetic resonance imaging (MRI) and for creating more accurate…

Medical Physics · Physics 2019-06-12 Andreas D. Lauritzen , Xenophon Papademetris , Sergei Turovets , John A. Onofrey

Deep learning techniques, particularly convolutional neural networks (CNNs), have gained traction for synthetic computed tomography (sCT) generation from Magnetic resonance imaging (MRI), Cone-beam computed tomography (CBCT) and PET. In…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Satoshi Kondo , Satoshi Kasai , Kousuke Hirasawa

In this work we present a method of automatic segmentation of defective skulls for custom cranial implant design and 3D printing purposes. Since such tissue models are usually required in patient cases with complex anatomical defects and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Oldřich Kodym , Michal Španěl , Adam Herout

Segmentation of magnetic resonance images (MRI) facilitates analysis of human brain development by delineating anatomical structures. However, in infants and young children, accurate segmentation is challenging due to development and…

Machine Learning · Computer Science 2026-04-01 Malte Hoffmann , Lilla Zöllei , Adrian V. Dalca

Precise 3D segmentation of infant brain tissues is an essential step towards comprehensive volumetric studies and quantitative analysis of early brain developement. However, computing such segmentations is very challenging, especially for…

Computer Vision and Pattern Recognition · Computer Science 2017-12-20 Jose Dolz , Christian Desrosiers , Li Wang , Jing Yuan , Dinggang Shen , Ismail Ben Ayed

Computed tomography (CT) equivalent information is needed for attenuation correction in PET imaging and for dose planning in radiotherapy. Prior work has shown that Gaussian mixture models can be used to generate a substitute CT (s-CT)…

Applications · Statistics 2016-09-29 Anders Hildeman , David Bolin , Jonas Wallin , Adam Johansson , Tufve Nyholm , Thomas Asklund , Jun Yu
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