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A vast majority of computation in the brain is performed by spiking neural networks. Despite the ubiquity of such spiking, we currently lack an understanding of how biological spiking neural circuits learn and compute in-vivo, as well as…

Neurons and Cognition · Quantitative Biology 2018-05-31 Friedemann Zenke , Surya Ganguli

Research showed that, the information transmitted in biological neurons is encoded in the instants of successive action potentials or their firing rate. In addition to that, in-vivo operation of the neuron makes measurement difficult and…

Neurons and Cognition · Quantitative Biology 2018-01-10 Ozgur Doruk , Kechen Zhang

Artificial Neural Network (ANN)-based inference on battery-powered devices can be made more energy-efficient by restricting the synaptic weights to be binary, hence eliminating the need to perform multiplications. An alternative, emerging,…

Machine Learning · Computer Science 2020-12-16 Hyeryung Jang , Nicolas Skatchkovsky , Osvaldo Simeone

Spike-timing dependent plasticity (STDP) which observed in the brain has proven to be important in biological learning. On the other hand, artificial neural networks use a different way to learn, such as Back-Propagation or Contrastive…

Neural and Evolutionary Computing · Computer Science 2021-06-10 Shiyuan Li

The problem of training spiking neural networks (SNNs) is a necessary precondition to understanding computations within the brain, a field still in its infancy. Previous work has shown that supervised learning in multi-layer SNNs enables…

Neural and Evolutionary Computing · Computer Science 2018-03-12 Amirhossein Tavanaei , Anthony S. Maida

Understanding cognitive flexibility and task-switching mechanisms in neural systems requires biologically plausible computational models. This tutorial presents a step-by-step approach to constructing a spiking neural network (SNN) that…

Neurons and Cognition · Quantitative Biology 2025-03-07 Ashwin Viswanathan Kannan , Madhumitha Ganesan

Neurons communicate with downstream systems via sparse and incredibly brief electrical pulses, or spikes. Using these events, they control various targets such as neuromuscular units, neurosecretory systems, and other neurons in connected…

Neurons and Cognition · Quantitative Biology 2026-03-17 Paolo Agliati , André Urbano , Pablo Lanillos , Nasir Ahmad , Marcel van Gerven , Sander Keemink

The energy-efficient and brain-like information processing abilities of Spiking Neural Networks (SNNs) have attracted considerable attention, establishing them as a crucial element of brain-inspired computing. One prevalent challenge…

Neural and Evolutionary Computing · Computer Science 2025-10-27 Zhichao Zhu , Yang Qi , Wenlian Lu , Zhigang Wang , Lu Cao , Jianfeng Feng

Humans possess the capability to reason at an abstract level and to structure information into abstract categories, but the underlying neural processes have remained unknown. Experimental evidence has recently emerged for the organization…

Neurons and Cognition · Quantitative Biology 2022-04-05 Michael G. Müller , Christos H. Papadimitriou , Wolfgang Maass , Robert Legenstein

This paper presents a spike-based model which employs neurons with functionally distinct dendritic compartments for classifying high dimensional binary patterns. The synaptic inputs arriving on each dendritic subunit are nonlinearly…

Neural and Evolutionary Computing · Computer Science 2014-11-26 Shaista Hussain , Shih-Chii Liu , Arindam Basu

This paper proposes a neuronal circuitry layout and synaptic plasticity principles that allow the (pyramidal) neuron to act as a "combinatorial switch". Namely, the neuron learns to be more prone to generate spikes given those combinations…

Biological Physics · Physics 2017-05-09 Marat M. Rvachev

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

Temporal coding is one approach to representing information in spiking neural networks. An example of its application is the location of sounds by barn owls that requires especially precise temporal coding. Dependent upon the azimuthal…

Neurons and Cognition · Quantitative Biology 2014-01-24 Thomas Pfeil , Anne-Christine Scherzer , Johannes Schemmel , Karlheinz Meier

Uncertainty in biological neural systems appears to be computationally beneficial rather than detrimental. However, in neuromorphic computing systems, device variability often limits performance, including accuracy and efficiency. In this…

Neural and Evolutionary Computing · Computer Science 2026-02-10 Huannan Zheng , Jingli Liu , Kezhou Yang

How neuronal circuits achieve credit assignment remains a central unsolved question in systems neuroscience. Various studies have suggested plausible solutions for back-propagating error signals through multi-layer networks. These purely…

Neurons and Cognition · Quantitative Biology 2023-12-12 Julian Rossbroich , Friedemann Zenke

Spike-timing-dependent plasticity(STDP) is a biological process of synaptic modification caused by the difference of firing order and timing between neurons. One of the neurodynamical roles of STDP is to form a macroscopic geometrical…

Neurons and Cognition · Quantitative Biology 2021-08-10 Hong-Gyu Yoon , Pilwon Kim

Spike Timing Dependent Plasticity is form of learning that has been demonstrated in real cortical tissue, but attempts to use it for artificial systems have not produced good results. This paper seeks to remedy this with two significant…

Neural and Evolutionary Computing · Computer Science 2020-07-01 Simon Davidson , Stephen B. Furber , Oliver Rhodes

Learning to produce spatiotemporal sequences is a common task that the brain has to solve. The same neural substrate may be used by the brain to produce different sequential behaviours. The way the brain learns and encodes such tasks…

Neurons and Cognition · Quantitative Biology 2020-07-01 Amadeus Maes , Mauricio Barahona , Claudia Clopath

A common view in the neuroscience community is that memory is encoded in the connection strength between neurons. This perception led artificial neural network models to focus on connection weights as the key variables to modulate learning.…

Neural and Evolutionary Computing · Computer Science 2022-02-22 Hananel Hazan , Simon Caby , Christopher Earl , Hava Siegelmann , Michael Levin

The timing of individual neuronal spikes is essential for biological brains to make fast responses to sensory stimuli. However, conventional artificial neural networks lack the intrinsic temporal coding ability present in biological…

Neural and Evolutionary Computing · Computer Science 2020-11-18 Iulia M. Comsa , Krzysztof Potempa , Luca Versari , Thomas Fischbacher , Andrea Gesmundo , Jyrki Alakuijala