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The design of molecules and materials with tailored properties is challenging, as candidate molecules must satisfy multiple competing requirements that are often difficult to measure or compute. While molecular structures, produced through…

Chemical Physics · Physics 2023-02-07 Julia Westermayr , Joe Gilkes , Rhyan Barrett , Reinhard J. Maurer

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

For optimization models to be used in practice, it is crucial that users trust the results. A key factor in this aspect is the interpretability of the solution process. A previous framework for inherently interpretable optimization models…

Optimization and Control · Mathematics 2026-02-13 Marc Goerigk , Michael Hartisch , Sebastian Merten , Kartikey Sharma

Pathways that describe the optimal evolution of energy systems across multiple decades are important in energy system research and policy literature, with net-zero and similar climate policies being common drivers behind them. While there…

Physics and Society · Physics 2026-05-12 Ivan Ruiz Manuel , Meijun Chen , Francesco Lombardi , Stefan Pfenninger-Lee

An important factor in the practical implementation of optimization models is the acceptance by the intended users. This is influenced among other factors by the interpretability of the solution process. Decision rules that meet this…

Machine Learning · Computer Science 2024-12-03 Marc Goerigk , Michael Hartisch , Sebastian Merten

With dramatic improvements in optimization software, the solution of large-scale problems that seemed intractable decades ago are now a routine task. This puts even more real-world applications into the reach of optimizers. At the same…

Optimization and Control · Mathematics 2023-03-07 Marc Goerigk , Michael Hartisch

Accurate exploration of protein conformational ensembles is essential for uncovering function but remains hard because molecular-dynamics (MD) simulations suffer from high computational costs and energy-barrier trapping. This paper presents…

Machine Learning · Computer Science 2025-11-14 Yuancheng Sun , Yuxuan Ren , Zhaoming Chen , Xu Han , Kang Liu , Qiwei Ye

The electrification of heating, cooling, and transportation to reach decarbonization targets calls for a rapid expansion of renewable technologies. Due to their decentral and intermittent nature, these technologies require robust planning…

Physics and Society · Physics 2022-03-01 Febin Kachirayil , Jann Michael Weinand , Fabian Scheller , Russell McKenna

The European Materials and Modelling Ontology (EMMO) is a top-level ontology designed by the European Materials Modelling Council to facilitate semantic interoperability between platforms, models, and tools in computational molecular…

Computational Engineering, Finance, and Science · Computer Science 2020-01-14 Martin Thomas Horsch , Silvia Chiacchiera , Youness Bami , Georg J. Schmitz , Gabriele Mogni , Gerhard Goldbeck , Emanuele Ghedini

The increasing number of Electric Vehicles (EVs) have led to rising energy demands which aggregates the burden on grid supply. A few solutions have been proposed to reduce grid load, for example, using storage systems for storing surplus…

Systems and Control · Electrical Eng. & Systems 2023-12-14 Ferheen Ayaz , Maziar Nekovee

The generation of synthetic natural gas from renewable electricity enables long-term energy storage and provides clean fuels for transportation. In this article, we analyze fully renewable Power-to-Methane systems using a high-resolution…

Physics and Society · Physics 2020-02-17 Simon Morgenthaler , Christopher Ball , Jan Koj , Wilhelm Kuckshinrichs , Dirk Witthaut

Compared with traditional design methods, generative design significantly attracts engineers in various disciplines. In thiswork, howto achieve the real-time generative design of optimized structures with various diversities and…

Computational Engineering, Finance, and Science · Computer Science 2024-01-23 Zongliang Du , Xinyu Ma , Wenyu Hao , Yuan Liang , Xiaoyu Zhang , Hongzhi Luo , Xu Guo

Generative machine learning has emerged as a powerful tool for design representation and exploration. However, its application is often constrained by the need for large datasets of existing designs and the lack of interpretability about…

Machine Learning · Computer Science 2025-08-13 Eric Seng , Hugh O'Connor , Adam Boyce , Josh J. Bailey , Anton van Beek

Climate neutrality paradigms put electricity systems at the core of a clean energy supply. At the same time, indirect electrification, with a potential uptake of hydrogen or derived fuel economy, plays a crucial role in decarbonising the…

General Economics · Economics 2025-05-27 Felix Frischmuth , Mattis Berghoff , Martin Braun , Philipp Haertel

Deep learning has recently been applied to various research areas of design optimization. This study presents the need and effectiveness of adopting deep learning for generative design (or design exploration) research area. This work…

Machine Learning · Computer Science 2020-05-27 Sangeun Oh , Yongsu Jung , Seongsin Kim , Ikjin Lee , Namwoo Kang

Energy infrastructure planning under uncertainty has become increasingly complex as electrification, interdependence between energy carriers, decarbonization, and extreme weather events reshape long-term investment decisions. This paper…

Systems and Control · Electrical Eng. & Systems 2026-04-14 Rahman Khorramfar , Aron Brenner , Lara Booth , Ana Rivera , Ruaridh Macdonald , Priya Donti , Saurabh Amin

Hydrogen can be produced from water, using electricity. The hydrogen can subsequently be kept in inventory in large quantities, unlike the electricity itself. This enables solar and wind energy generation to occur asynchronously from its…

Optimization and Control · Mathematics 2024-01-05 Umur Hasturk , Albert H. Schrotenboer , Evrim Ursavas , Kees Jan Roodbergen

Energy efficiency is a crucial requirement for enabling powerful artificial intelligence applications at the microedge. Hardware acceleration with frugal architectural allocation is an effective method for reducing energy. Many emerging…

Artificial Intelligence · Computer Science 2023-05-23 Rishad Shafik , Tousif Rahman , Adrian Wheeldon , Ole-Christoffer Granmo , Alex Yakovlev

The intermittent nature of renewable energy resources such as wind and solar causes the energy supply to be less predictable leading to possible mismatches in the power network. To this end, hydrogen production and storage can provide a…

Systems and Control · Electrical Eng. & Systems 2021-08-03 Arjen T. Veenstra , Albert H. Schrotenboer , Michiel A. J. Uit het Broek , Evrim Ursavas

This article proposes a fundamental methodological shift in the modelling of policy interventions for sustainability transitions in order to account for complexity (e.g. self-reinforcing mechanism arising from multi-agent interactions) and…

Physics and Society · Physics 2016-03-23 J. -F. Mercure , H. Pollitt , A. M. Bassi , J. E Viñuales , N. R. Edwards