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Deformable image registration poses a challenging problem where, unlike most deep learning tasks, a complex relationship between multiple coordinate systems has to be considered. Although data-driven methods have shown promising…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Vasiliki Sideri-Lampretsa , Nil Stolt-Ansó , Huaqi Qiu , Julian McGinnis , Wenke Karbole , Martin Menten , Daniel Rueckert

The potential of deep neural networks in skin lesion classification has already been demonstrated to be on-par if not superior to the dermatologists diagnosis. However, the performance of these models usually deteriorates when the test data…

Computer Vision and Pattern Recognition · Computer Science 2023-10-06 Sireesha Chamarthi , Katharina Fogelberg , Roman C. Maron , Titus J. Brinker , Julia Niebling

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Longitudinal image registration is challenging and has not yet benefited from major performance improvements thanks to deep-learning. Inspired by Deep Image Prior, this paper introduces a different use of deep architectures as regularizers…

Domain generalization (DG) is a fundamental yet very challenging research topic in machine learning. The existing arts mainly focus on learning domain-invariant features with limited source domains in a static model. Unfortunately, there is…

Machine Learning · Computer Science 2022-05-30 Zhishu Sun , Zhifeng Shen , Luojun Lin , Yuanlong Yu , Zhifeng Yang , Shicai Yang , Weijie Chen

Accurate deformable 4-dimensional (4D) (3-dimensional in space and time) medical images registration is essential in a variety of medical applications. Deep learning-based methods have recently gained popularity in this area for the…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 Yunlu Zhang , Xue Wu , H. Michael Gach , Harold Li , Deshan Yang

The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…

Image and Video Processing · Electrical Eng. & Systems 2019-09-09 Abdullah Nazib , Clinton Fookes , Dimitri Perrin

Deep Neural Networks have shown great promise on a variety of downstream applications; but their ability to adapt and generalize to new data and tasks remains a challenge. However, the ability to perform few or zero-shot adaptation to novel…

Machine Learning · Computer Science 2020-10-14 Samarth Sinha , Karsten Roth , Anirudh Goyal , Marzyeh Ghassemi , Hugo Larochelle , Animesh Garg

Medical image registration drives quantitative analysis across organs, modalities, and patient populations. Recent deep learning methods often combine low-level "trend-driven" computational blocks from computer vision, such as large-kernel…

Image and Video Processing · Electrical Eng. & Systems 2025-12-02 Bailiang Jian , Jiazhen Pan , Rohit Jena , Morteza Ghahremani , Hongwei Bran Li , Daniel Rueckert , Christian Wachinger , Benedikt Wiestler

Deep Neural Networks have exhibited considerable success in various visual tasks. However, when applied to unseen test datasets, state-of-the-art models often suffer performance degradation due to domain shifts. In this paper, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Jintao Guo , Lei Qi , Yinghuan Shi

Deep neural networks often suffer performance drops when test data distribution differs from training data. Domain Generalization (DG) aims to address this by focusing on domain-invariant features or augmenting data for greater diversity.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Nam Duong Tran , Nam Nguyen Phuong , Hieu H. Pham , Phi Le Nguyen , My T. Thai

Classical deformable registration techniques achieve impressive results and offer a rigorous theoretical treatment, but are computationally intensive since they solve an optimization problem for each image pair. Recently, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Adrian V. Dalca , Guha Balakrishnan , John Guttag , Mert R. Sabuncu

Recently, cross domain transfer has been applied for unsupervised image restoration tasks. However, directly applying existing frameworks would lead to domain-shift problems in translated images due to lack of effective supervision.…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Wenchao Du , Hu Chen , Hongyu Yang

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Modern medical image registration approaches predict deformations using deep networks. These approaches achieve state-of-the-art (SOTA) registration accuracy and are generally fast. However, deep learning (DL) approaches are, in contrast to…

Deep Learning in Image Registration (DLIR) methods have been tremendously successful in image registration due to their speed and ability to incorporate weak label supervision at training time. However, existing DLIR methods forego many of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Rohit Jena , Pratik Chaudhari , James C. Gee

This paper presents NimbleReg, a light-weight deep-learning (DL) framework for diffeomorphic image registration leveraging surface representation of multiple segmented anatomical regions. Deep learning has revolutionized image registration…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Antoine Legouhy , Ross Callaghan , Nolah Mazet , Vivien Julienne , Hojjat Azadbakht , Hui Zhang

Diffeomorphic deformable image registration is crucial in many medical image studies, as it offers unique, special properties including topology preservation and invertibility of the transformation. Recent deep learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 Tony C. W. Mok , Albert C. S. Chung