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While it is well known that high levels of prenatal alcohol exposure (PAE) result in significant cognitive deficits in children, the exact nature of the dose response is less well understood. In particular, there is a pressing need to…

Network meta-analysis (NMA) combines evidence from multiple trials to compare the effectiveness of a set of interventions. In public health research, interventions are often complex, made up of multiple components or features. This makes it…

Methodology · Statistics 2024-01-04 Annabel L Davies , Julian P T Higgins

Biomedical researchers usually study the effects of certain exposures on disease risks among a well-defined population. To achieve this goal, the gold standard is to design a trial with an appropriate sample from that population. Due to the…

Applications · Statistics 2019-11-18 Cheng Zheng , Sayan Dasgupta , Yuxiang Xie , Asad Haris , Ying Qing Chen

Diabetes mellitus (DM) is a global health issue of significance that must be diagnosed as early as possible and managed well. This study presents a framework for diabetes prediction using Machine Learning (ML) models, complemented with…

Machine Learning · Computer Science 2025-02-13 Pir Bakhsh Khokhar , Viviana Pentangelo , Fabio Palomba , Carmine Gravino

Motivated by the study of pollution trends in the city of Bergen, we introduce a flexible statistical framework for modeling multivariate air pollution data via a nonhomogeneous Hidden Semi-Markov Vector Auto-Regression. The hidden process…

This manuscript presents a novel Bayesian varying coefficient quantile regression (BVCQR) model designed to assess the longitudinal effects of chemical exposure mixtures on children's neurodevelopment. Recognizing the complexity and…

Applications · Statistics 2024-04-22 Wei Jia , Roman Jandarov

Machine learning is susceptible to poisoning attacks, in which an attacker controls a small fraction of the training data and chooses that data with the goal of inducing some behavior unintended by the model developer in the trained model.…

Machine Learning · Computer Science 2023-11-21 Evan Rose , Fnu Suya , David Evans

Surveys of microbial biodiversity such as the Earth Microbiome Project (EMP) and the Human Microbiome Project (HMP) have revealed robust ecological patterns across different environments. A major goal in ecology is to leverage these…

Populations and Evolution · Quantitative Biology 2020-03-05 Robert Marsland , Wenping Cui , Pankaj Mehta

Childhood obesity is a major public health concern. Multidisciplinary pediatric weight management programs are considered standard treatment for children with obesity and severe obesity who are not able to be successfully managed in the…

Machine Learning · Computer Science 2022-03-08 Hamed Fayyaz , Thao-Ly T. Phan , H. Timothy Bunnell , Rahmatollah Beheshti

Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-09 Karan Daga , Siddharth Agarwal , Zaeem Moti , Matthew BK Lee , Munaib Din , David Wood , Marc Modat , Thomas C Booth

Evaluating the health effects of complex environmental mixtures remains a central challenge in environmental health research. Existing approaches vary in their flexibility, interpretability, scalability, and support for diverse outcome…

Applications · Statistics 2025-12-15 Hyungrok Do , Yuyan Wang , Mengling Liu , Myeonggyun Lee

Electronic health record (EHR) data are increasingly used for biomedical research, but these data have recognized data quality challenges. Data validation is necessary to use EHR data with confidence, but limited resources typically make…

Developmental epidemiology commonly focuses on assessing the association between multiple early life exposures and childhood health. Statistical analyses of data from such studies focus on inferring the contributions of individual…

Applications · Statistics 2024-10-31 Glenn Palmer , Amy H. Herring , David B. Dunson

This paper aims to explore models based on the extreme gradient boosting (XGBoost) approach for business risk classification. Feature selection (FS) algorithms and hyper-parameter optimizations are simultaneously considered during model…

Machine Learning · Statistics 2019-01-25 Yan Wang , Xuelei Sherry Ni

This study investigates crash severity risk modeling strategies for work zones involving large vehicles (i.e., trucks, buses, and vans) under crash data imbalance between low-severity (LS) and high-severity (HS) crashes. We utilized crash…

Machine Learning · Computer Science 2026-02-24 Abdullah Al Mamun , Abyad Enan , Debbie A. Indah , Judith Mwakalonge , Gurcan Comert , Mashrur Chowdhury

Fetal health is a critical concern during pregnancy as it can impact the well-being of both the mother and the baby. Regular monitoring and timely interventions are necessary to ensure the best possible outcomes. While there are various…

Machine Learning · Computer Science 2023-05-30 Md. Simul Hasan Talukder , Sharmin Akter

Machine Learning (ML) models trained on complex health surveys such as the National Health and Nutrition Examination Survey (NHANES) often ignore primary sampling units, stratification variables, and sampling weights. This practice violates…

Machine Learning · Statistics 2026-05-12 YongKyung Oh , Henry W. Zheng , Jeffrey Feng , Alex A. T. Bui

Maternal exposure to air pollution during pregnancy has a substantial public health impact. Epidemiological evidence supports an association between maternal exposure to air pollution and low birth weight. A popular method to estimate this…

This paper integrates deep neural networks (DNNs) into structural economic models to increase flexibility and capture rich heterogeneity while preserving interpretability. Economic structure and machine learning are complements in empirical…

Econometrics · Economics 2025-04-28 Max H. Farrell , Tengyuan Liang , Sanjog Misra

Machine learning models trained on real-world data may inadvertently make biased predictions that negatively impact marginalized communities. Reweighting, which assigns a weight to each data point used during model training, can mitigate…

Machine Learning · Computer Science 2026-03-20 Anil K. Saini , Jose Guadalupe Hernandez , Emily F. Wong , Debanshi Misra , Tiffani J. Bright , Jason H. Moore