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Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Yihao Liu , Zhihao Cui , Liming Li , Junjie You , Xinle Feng , Jianxin Wang , Xiangyu Wang , Qing Liu , Minghua Wu

Although melanoma occurs more rarely than several other skin cancers, patients' long term survival rate is extremely low if the diagnosis is missed. Diagnosis is complicated by a high discordance rate among pathologists when distinguishing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Sean Grullon , Vaughn Spurrier , Jiayi Zhao , Corey Chivers , Yang Jiang , Kiran Motaparthi , Michael Bonham , Julianna Ianni

Whole slide images (WSI) provide valuable phenotypic information for histological assessment and malignancy grading of tumors. The WSI-based grading promises to provide rapid diagnostic support and facilitate digital health. Currently, the…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Lipei Zhang , Yiran Wei , Ying Fu , Stephen Price , Carola-Bibiane Schönlieb , Chao Li

Clinicians usually combine information from multiple sources to achieve the most accurate diagnosis, and this has sparked increasing interest in leveraging multimodal deep learning for diagnosis. However, in real clinical scenarios, due to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Kai Han , Chongwen Lyu , Lele Ma , Chengxuan Qian , Siqi Ma , Zheng Pang , Jun Chen , Zhe Liu

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

Multiple Instance Learning (MIL) has advanced WSI analysis but struggles with the complexity and heterogeneity of WSIs. Existing MIL methods face challenges in aggregating diverse patch information into robust WSI representations. While…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Beidi Zhao , SangMook Kim , Hao Chen , Chen Zhou , Zu-hua Gao , Gang Wang , Xiaoxiao Li

Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Xianrui Li , Yufei Cui , Jun Li , Antoni B. Chan

Deep neural network-based medical image classifications often use "hard" labels for training, where the probability of the correct category is 1 and those of others are 0. However, these hard targets can drive the networks over-confident…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Dong Wei , Shilei Cao , Kai Ma , Yefeng Zheng

This paper reports the method and evaluation results of MedAusbild team for ISIC challenge task. Since early 2017, our team has worked on melanoma classification [1][6], and has employed deep learning since beginning of 2018 [7]. Deep…

Machine Learning · Computer Science 2018-07-25 Sara Nasiri , Matthias Jung , Julien Helsper , Madjid Fathi

Modern high-throughput sequencing technologies have enabled us to profile multiple molecular modalities from the same single cell, providing unprecedented opportunities to assay celluar heterogeneity from multiple biological layers.…

Machine Learning · Statistics 2022-05-20 Pengcheng Zeng , Zhixiang Lin

Multimodal deep learning for cancer prognosis is commonly assumed to benefit from synergistic cross-modal interactions, yet this assumption has not been directly tested in survival prediction settings. This work adapts InterSHAP, a Shapley…

Machine Learning · Computer Science 2026-04-15 Iain Swift , JingHua Ye , Ruairi O'Reilly

The color of skin lesions is an important diagnostic feature for identifying malignant melanoma and other skin diseases. Typical colors associated with melanocytic lesions include tan, brown, black, red, white, and blue gray. This study…

Quantitative Methods · Quantitative Biology 2026-01-30 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

Kinship verification is a long-standing research challenge in computer vision. The visual differences presented to the face have a significant effect on the recognition capabilities of the kinship systems. We argue that aggregating multiple…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Guan-Nan Dong , Chi-Man Pun , Zheng Zhang

In this study, we introduce a multi-modal approach that efficiently integrates multi-scale clinical and dermoscopy features within a single network, thereby substantially reducing model parameters. The proposed method includes three novel…

Image and Video Processing · Electrical Eng. & Systems 2024-03-31 Peng Tang , Tobias Lasser

Multiple Instance Learning (MIL) is a sub-domain of classification problems with positive and negative labels and a "bag" of inputs, where the label is positive if and only if a positive element is contained within the bag, and otherwise is…

Machine Learning · Statistics 2023-10-30 Edward Raff , James Holt

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Colorectal cancer is one of the most common and lethal cancers and colorectal cancer liver metastases (CRLM) is the major cause of death in patients with colorectal cancer. Multifocality occurs frequently in CRLM, but is relatively…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Jianan Chen , Helen M. C. Cheung , Laurent Milot , Anne L. Martel

Deep models, e.g., CNNs and Vision Transformers, have achieved impressive achievements in many vision tasks in the closed world. However, novel classes emerge from time to time in our ever-changing world, requiring a learning system to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Da-Wei Zhou , Qi-Wei Wang , Zhi-Hong Qi , Han-Jia Ye , De-Chuan Zhan , Ziwei Liu

Multi-domain task-incremental learning requires a model to sequentially acquire knowledge across visually diverse domains without forgetting prior tasks, and without access to task identity at inference. Parameter-efficient methods built on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Sriram Mandalika

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

Artificial Intelligence · Computer Science 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta