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In recent years, the machine learning community has increasingly embraced the optimal transport (OT) framework for modeling distributional relationships. In this work, we introduce a sample-based neural solver for computing the Wasserstein…

Machine Learning · Computer Science 2026-02-26 Hailiang Liu , Yan-Han Chen

We propose a novel approach based on optimal transport (OT) for tackling the problem of highly mixed data in blind hyperspectral unmixing. Our method constrains the distribution of the estimated abundance matrix to resemble a targeted…

Image and Video Processing · Electrical Eng. & Systems 2025-09-26 D. Doutsas , B. Figliuzzi

The goal of this paper is to introduce a new theoretical framework for Optimal Transport (OT), using the terminology and techniques of Fully Probabilistic Design (FPD). Optimal Transport is the canonical method for comparing probability…

Artificial Intelligence · Computer Science 2022-12-29 Sarah Boufelja Y. , Anthony Quinn , Martin Corless , Robert Shorten

We introduce sliced optimal transport dataset distance (s-OTDD), a model-agnostic, embedding-agnostic approach for dataset comparison that requires no training, is robust to variations in the number of classes, and can handle disjoint label…

Machine Learning · Computer Science 2025-05-16 Khai Nguyen , Hai Nguyen , Tuan Pham , Nhat Ho

The matching principles behind optimal transport (OT) play an increasingly important role in machine learning, a trend which can be observed when OT is used to disambiguate datasets in applications (e.g. single-cell genomics) or used to…

Machine Learning · Statistics 2022-09-16 Meyer Scetbon , Marco Cuturi

Protein sequence alignment is a cornerstone of bioinformatics, traditionally approached using dynamic programming (DP) algorithms that find an optimal sequential path. This paper introduces UniOTalign, a novel framework that recasts…

Quantitative Methods · Quantitative Biology 2025-10-09 Yue Hu , Zanxia Cao , Yingchao Liu

Optimal transport (\OT) theory defines a powerful set of tools to compare probability distributions. \OT~suffers however from a few drawbacks, computational and statistical, which have encouraged the proposal of several regularized variants…

Machine Learning · Statistics 2019-10-29 Tam Le , Makoto Yamada , Kenji Fukumizu , Marco Cuturi

Transport systems on networks are crucial in various applications, but face a significant risk of being adversely affected by unforeseen circumstances such as disasters. The application of entropy-regularized optimal transport (OT) on graph…

Machine Learning · Computer Science 2025-05-07 Koshi Oishi , Yota Hashizume , Tomohiko Jimbo , Hirotaka Kaji , Kenji Kashima

The automated analysis of flow cytometry measurements is an active research field. We introduce a new algorithm, referred to as CytOpT, using regularized optimal transport to directly estimate the different cell population proportions from…

Applications · Statistics 2022-07-01 Paul Freulon , Jérémie Bigot , Boris P. Hejblum

In many applications of optimal transport (OT), the object of primary interest is the optimal transport map. This map rearranges mass from one probability distribution to another in the most efficient way possible by minimizing a specified…

Statistics Theory · Mathematics 2025-06-25 Sivaraman Balakrishnan , Tudor Manole , Larry Wasserman

Optimal transport tools (OTT-JAX) is a Python toolbox that can solve optimal transport problems between point clouds and histograms. The toolbox builds on various JAX features, such as automatic and custom reverse mode differentiation,…

Machine Learning · Computer Science 2022-01-31 Marco Cuturi , Laetitia Meng-Papaxanthos , Yingtao Tian , Charlotte Bunne , Geoff Davis , Olivier Teboul

We statistically analyze empirical plug-in estimators for unbalanced optimal transport (UOT) formalisms, focusing on the Kantorovich-Rubinstein distance, between general intensity measures based on observations from spatio-temporal point…

Statistics Theory · Mathematics 2025-09-05 Marina Struleva , Shayan Hundrieser , Dominic Schuhmacher , Axel Munk

We propose a novel amortized optimization method for predicting optimal transport (OT) plans across multiple pairs of measures by leveraging Kantorovich potentials derived from sliced OT. We introduce two amortization strategies:…

Machine Learning · Statistics 2026-04-17 Minh-Phuc Truong , Khai Nguyen

Optimal Transport (OT) problem aims to find a transport plan that bridges two distributions while minimizing a given cost function. OT theory has been widely utilized in generative modeling. In the beginning, OT distance has been used as a…

Machine Learning · Computer Science 2024-03-08 Jaemoo Choi , Jaewoong Choi , Myungjoo Kang

Optimal transport aligns samples across distributions by minimizing the transportation cost between them, e.g., the geometric distances. Yet, it ignores coherence structure in the data such as clusters, does not handle outliers well, and…

Machine Learning · Computer Science 2023-05-31 Ching-Yao Chuang , Stefanie Jegelka , David Alvarez-Melis

In many real-world settings--e.g., single-cell RNA sequencing, mobility sensing, and environmental monitoring--data are observed only as temporally aggregated snapshots collected over finite time windows, often with noisy or uncertain…

Machine Learning · Computer Science 2026-05-25 Keisuke Kawano , Takuro Kutsuna , Naoki Hayashi , Yasushi Esaki , Hidenori Tanaka

Optimal transport (OT) and Gromov-Wasserstein (GW) alignment provide interpretable geometric frameworks for comparing, transforming, and aggregating heterogeneous datasets -- tasks ubiquitous in data science and machine learning. Because…

Machine Learning · Computer Science 2025-12-04 Sanjit Dandapanthula , Aleksandr Podkopaev , Shiva Prasad Kasiviswanathan , Aaditya Ramdas , Ziv Goldfeld

The optimal transport (OT) map is a geometry-driven transformation between high-dimensional probability distributions which underpins a wide range of tasks in statistics, applied probability, and machine learning. However, existing…

Machine Learning · Statistics 2025-12-11 Sloan Nietert , Ziv Goldfeld

We study multi-marginal optimal transport (MOT) problems where the underlying cost has a graphical structure. These graphical multi-marginal optimal transport problems have found applications in several domains including traffic flow…

Optimization and Control · Mathematics 2025-12-02 Jiaojiao Fan , Isabel Haasler , Qinsheng Zhang , Johan Karlsson , Yongxin Chen

We study the use of amortized optimization to predict optimal transport (OT) maps from the input measures, which we call Meta OT. This helps repeatedly solve similar OT problems between different measures by leveraging the knowledge and…

Machine Learning · Computer Science 2023-06-06 Brandon Amos , Samuel Cohen , Giulia Luise , Ievgen Redko