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AI agents are increasingly useful for biological data analysis, but existing benchmarks mostly test broad biological knowledge, executable workflows, or localized analysis steps rather than end-to-end scientific reasoning over spatial…

Artificial Intelligence · Computer Science 2026-05-28 Ian Diks , Harihara Muralidharan , Tim Proctor , Kenny Workman

As single-cell RNA sequencing datasets grow in adoption, scale, and complexity, data analysis remains a bottleneck for many research groups. Although frontier AI agents have improved dramatically at software engineering and general data…

Genomics · Quantitative Biology 2026-02-11 Kenny Workman , Zhen Yang , Harihara Muralidharan , Aidan Abdulali , Hannah Le

AI agents may soon become capable of autonomously completing valuable, long-horizon tasks in diverse domains. Current benchmarks either do not measure real-world tasks, or are not sufficiently difficult to meaningfully measure frontier…

While spatial foundation models have demonstrated impressive performance on standard datasets, a critical question remains: are they truly all-round players capable of generalizing robustly across diverse downstream tasks, arbitrary…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Haosong Peng , Hao Li , Jiaqi Chen , Yuhao Pan , Runmao Yao , Yalun Dai , Fushuo Huo , Fangzhou Hong , Zhaoxi Chen , Haozhao Wang , Dingwen Zhang , Ziwei Liu , Wenchao Xu

AI agents hold the potential to revolutionize scientific productivity by automating literature reviews, replicating experiments, analyzing data, and even proposing new directions of inquiry; indeed, there are now many such agents, ranging…

Large Language Models (LLMs) and LLM-based agents show great promise in accelerating scientific research. Existing benchmarks for measuring this potential and guiding future development continue to evolve from pure recall and rote knowledge…

Workspace learning requires AI agents to identify, reason over, exploit, and update explicit and implicit dependencies among heterogeneous files in a worker's workspace, enabling them to complete both routine and advanced tasks effectively.…

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and…

LLM agents are increasingly deployed as executable systems that use tools, modify workspaces, and produce concrete artifacts. In such workflows, performance depends not only on the base model, but also on the harness: the system layer that…

Artificial Intelligence · Computer Science 2026-05-28 Yilun Yao , Xinyu Tan , Chao-Hsuan Liu , Yaoming Li , Zhengyang Wang , Wenhan Yu , Zhewen Tan , Yuxuan Tian , Guangxiang Zhao , Lin Sun , Xiangzheng Zhang , Tong Yang

As autonomous coding agents become capable of handling increasingly long-horizon tasks, they have gradually demonstrated the potential to complete end-to-end software development. Although existing benchmarks have recently evolved from…

Software Engineering · Computer Science 2026-05-19 Qingnan Ren , Shun Zou , Shiting Huang , Ziao Zhang , Kou Shi , Zhen Fang , Yiming Zhao , Yu Zeng , Qisheng Su , Lin Chen , Yong Wang , Zehui Chen , Xiangxiang Chu , Feng Zhao

As LLM-based agents are increasingly deployed in real-life scenarios, existing benchmarks fail to capture their inherent complexity of handling extensive information, leveraging diverse resources, and managing dynamic user interactions. To…

Computation and Language · Computer Science 2025-10-20 Wei He , Yueqing Sun , Hongyan Hao , Xueyuan Hao , Zhikang Xia , Qi Gu , Chengcheng Han , Dengchang Zhao , Hui Su , Kefeng Zhang , Man Gao , Xi Su , Xiaodong Cai , Xunliang Cai , Yu Yang , Yunke Zhao

Modern AI progress has been driven by ML methods that are generalizable across settings and scalable to larger regimes. As large language models demonstrate advanced capabilities in reasoning, coding, and engineering tasks, it is…

AI models are increasingly deployed in live clinical environments where they must perform reliably across complex, high-stakes workflows that standard training and validation datasets were never designed to capture. Evaluating these systems…

Artificial Intelligence · Computer Science 2026-05-12 Prasanna Desikan , Harshit Rajgarhia , Shivali Dalmia , Ananya Mantravadi

Spatial competence is the quality of maintaining a consistent internal representation of an environment and using it to infer discrete structure and plan actions under constraints. Prevailing spatial evaluations for large models are limited…

Artificial Intelligence · Computer Science 2026-04-14 Jash Vira , Ashley Harris

Optimism for accelerating scientific discovery with AI continues to grow. Current applications of AI in scientific research range from training dedicated foundation models on scientific data to agentic autonomous hypothesis generation…

Frontier AI agents show increasing promise as scientific research assistants, and may eventually be useful for extended, open-ended research workflows. However, in order to use agents for novel research, we must first assess the underlying…

Video production workflows offer a rich and demanding arena for evaluating multimodal AI agents: they require composite capabilities across text, image, audio, and video understanding, along with long-horizon planning, and tool use. To this…

Cryptography and Security · Computer Science 2026-05-28 Zongheng Cao , Yi Zheng , Rui Song , Xinyu Hu

We introduce DRBench, a benchmark for evaluating AI agents on complex, open-ended deep research tasks in enterprise settings. Unlike prior benchmarks that focus on simple questions or web-only queries, DRBench evaluates agents on multi-step…

Existing AI benchmarks for software automation rarely combine cross-application coordination, autonomous API discovery, and policy adherence. Real business workflows demand all three: a single task may span a CRM, inbox, calendar, and…

Artificial Intelligence · Computer Science 2026-04-22 Daniel Shepard , Robin Salimans
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