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Trustworthy clinical AI requires that performance gains reflect genuine evidence integration rather than surface-level artifacts. We evaluate 12 open-weight vision-language models (VLMs) on binary classification across two clinical…
Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…
The emergence of foundation models in neuroimaging is driven by the increasing availability of large-scale and heterogeneous brain imaging datasets. Recent advances in self-supervised learning, particularly reconstruction-based objectives,…
A fundamental challenge in neuroscience is to decode mental states from brain activity. While functional magnetic resonance imaging (fMRI) offers a non-invasive approach to capture brain-wide neural dynamics with high spatial precision,…
Whole brain segmentation on a structural magnetic resonance imaging (MRI) is essential in non-invasive investigation for neuroanatomy. Historically, multi-atlas segmentation (MAS) has been regarded as the de facto standard method for whole…
Light sheet fluorescence microscopy (LSM) enables high-resolution, three-dimensional (3D) imaging of biological specimens, providing rich volumetric data for studying cellular organization, pathology, and vascular networks. However, the…
Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…
Functional magnetic resonance imaging (fMRI) data contain complex spatiotemporal dynamics, thus researchers have developed approaches that reduce the dimensionality of the signal while extracting relevant and interpretable dynamics. Models…
We study the problem of training self-supervised foundation models for functional MRI. Our main contributions are: (1) we introduce a new model family (CortexMAE) trained using the masked autoencoder framework on 2.1K hours of open fMRI…
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder impacting social and behavioral development. Resting-state fMRI, a non-invasive tool for capturing brain connectivity patterns, aids in early ASD diagnosis and differentiation…
Foundation vision or vision-language models are trained on large unlabeled or noisy data and learn robust representations that can achieve impressive zero- or few-shot performance on diverse tasks. Given these properties, they are a natural…
Large language models (LLMs) have demonstrated exceptional proficiency in understanding and generating human language, but efficient inference on resource-constrained embedded devices remains challenging due to large model sizes and…
Magnetic Resonance Spectroscopic Imaging (MRSI) is a powerful tool for non-invasive mapping of brain metabolites, providing critical insights into neurological conditions. However, its utility is often limited by missing or corrupted data…
Volumetric data compression is critical in fields like medical imaging, scientific simulation, and entertainment. We introduce a structure-free neural compression method combining Fourierfeature encoding with selective voxel sampling,…
Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…
Data scarcity is a major limiting factor for applying modern machine learning techniques to clinical tasks. Although sufficient data exists for some well-studied medical tasks, there remains a long tail of clinically relevant tasks with…
Spatio-temporal fetal brain atlases are important for characterizing normative neurodevelopment and identifying congenital anomalies. However, existing atlas construction pipelines necessitate days for slice-to-volume reconstruction (SVR)…
The landscape of publicly available vision foundation models (VFMs), such as CLIP and Segment Anything Model (SAM), is expanding rapidly. VFMs are endowed with distinct capabilities stemming from their pre-training objectives. For instance,…
Although developed functional magnetic resonance imaging (fMRI) registration algorithms based on deep learning have achieved a certain degree of alignment of functional area, they underutilized fine structural information. In this paper, we…
Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…