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Phylogenetic trees are the fundamental mathematical representation of evolutionary processes in biology. They are also objects of interest in pure mathematics, such as algebraic geometry and combinatorics, due to their discrete geometry.…

Metric Geometry · Mathematics 2022-07-01 Anthea Monod , Bo Lin , Ruriko Yoshida , Qiwen Kang

We study the behavior of phylogenetic tree shapes in the tropical geometric interpretation of tree space. Tree shapes are formally referred to as tree topologies; a tree topology can also be thought of as a tree combinatorial type, which is…

Combinatorics · Mathematics 2023-01-25 Bo Lin , Anthea Monod , Ruriko Yoshida

Phylogenetic trees summarize evolutionary relationships. The Billera-Holmes-Vogtmann (BHV) space for comparing phylogenetic trees has many elegant mathematical properties, but it does not encompass trees with differing leaf sets. To…

Populations and Evolution · Quantitative Biology 2025-08-12 Maria Alejandra Valdez Cabrera , Amy D Willis

In this paper we study tropicalization of Grassmannian and linear varieties. In particular, we study the tropical linear spaces cor- responding to the phylogenetic trees. We prove that corresponding to each subtree of the phylogenetic tree…

Combinatorics · Mathematics 2014-05-01 Ambedkar Dukkipati , Aritra Sen

Phylogenomics is a new field which applies to tools in phylogenetics to genome data. Due to a new technology and increasing amount of data, we face new challenges to analyze them over a space of phylogenetic trees. Because a space of…

Combinatorics · Mathematics 2020-05-15 Ruriko Yoshida

The metric space of phylogenetic trees defined by Billera, Holmes, and Vogtmann, which we refer to as BHV space, provides a natural geometric setting for describing collections of trees on the same set of taxa. However, it is sometimes…

Populations and Evolution · Quantitative Biology 2018-07-12 Gillian Grindstaff , Megan Owen

In tropical algebraic geometry, the solution sets of polynomial equations are piecewise-linear. We introduce the tropical variety of a polynomial ideal, and we identify it with a polyhedral subcomplex of the Grobner fan. The tropical…

Algebraic Geometry · Mathematics 2007-05-23 David Speyer , Bernd Sturmfels

A classic problem in computational biology is constructing a phylogenetic tree given a set of distances between n species. In most cases, a tree structure is too constraining. We consider a circular split network, a generalization of a tree…

Combinatorics · Mathematics 2016-07-26 Satyan L. Devadoss , Samantha Petti

We study the geometry of metrics and convexity structures on the space of phylogenetic trees, which is here realized as the tropical linear space of all \ ultrametrics. The ${\rm CAT}(0)$-metric of Billera-Holmes-Vogtman arises from the…

Metric Geometry · Mathematics 2018-02-19 Bo Lin , Bernd Sturmfels , Xiaoxian Tang , Ruriko Yoshida

Phylogenetic inference, grounded in molecular evolution models, is essential for understanding the evolutionary relationships in biological data. Accounting for the uncertainty of phylogenetic tree variables, which include tree topologies…

Machine Learning · Computer Science 2023-12-04 Takahiro Mimori , Michiaki Hamada

The phylogenetic tree space introduced by Billera, Holmes, and Vogtmann (BHV tree space) is a CAT(0) continuous space that represents trees with edge weights with an intrinsic geodesic distance measure. The geodesic distance measure unique…

Quantitative Methods · Quantitative Biology 2021-10-29 Yingying Ren , Sihan Zha , Jingwen Bi , José A. Sanchez , Cara Monical , Michelle Delcourt , Rosemary K. Guzman , Ruth Davidson

In 2004 Pachter and Speyer introduced the higher dissimilarity maps for phylogenetic trees and asked two important questions about their relation to the tropical Grassmannian. Multiple authors, using independent methods, answered…

Algebraic Geometry · Mathematics 2022-05-11 Alessio Caminata , Noah Giansiracusa , Han-Bom Moon , Luca Schaffler

We propose a new space of phylogenetic trees which we call wald space. The motivation is to develop a space suitable for statistical analysis of phylogenies, but with a geometry based on more biologically principled assumptions than…

Probability · Mathematics 2020-09-21 Maryam K. Garba , Tom M. W. Nye , Jonas Lueg , Stephan F. Huckemann

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Populations and Evolution · Quantitative Biology 2024-03-26 Mingyang Zhou , Zichao Yan , Elliot Layne , Nikolay Malkin , Dinghuai Zhang , Moksh Jain , Mathieu Blanchette , Yoshua Bengio

When we apply comparative phylogenetic analyses to genome data, it is a well-known problem and challenge that some of given species (or taxa) often have missing genes. In such a case, we have to impute a missing part of a gene tree from a…

Populations and Evolution · Quantitative Biology 2023-07-06 Ruriko Yoshida

The space of phylogenetic trees arises naturally in tropical geometry as the tropical Grassmannian. Tropical geometry therefore suggests a natural notion of a tropical path between two trees, given by a tropical line segment in the tropical…

Combinatorics · Mathematics 2023-12-06 Shelby Cox

A phylogenetic tree is an acyclic graph with distinctly labeled leaves, whose internal edges have a positive weight. Given a set of n leaves, the collection of all phylogenetic trees with this leaf set can be assembled into a metric cube…

Combinatorics · Mathematics 2019-04-02 Gillian Grindstaff

Phylogenetic networks extend phylogenetic trees to allow for modeling reticulate evolutionary processes such as hybridization. They take the shape of a rooted, directed, acyclic graph, and when parameterized with evolutionary parameters,…

Populations and Evolution · Quantitative Biology 2018-08-28 R. A. L. Elworth , H. A. Ogilvie , J. Zhu , L. Nakhleh

Phylogenetics is the study of the evolutionary relationships between organisms. One of the main challenges in the field is to take biological data for a group of organisms and to infer an evolutionary tree, a graph that represents these…

Populations and Evolution · Quantitative Biology 2019-06-05 Elizabeth Gross , Colby Long , Joseph Rusinko

Phylogenetic algebraic geometry is concerned with certain complex projective algebraic varieties derived from finite trees. Real positive points on these varieties represent probabilistic models of evolution. For small trees, we recover…

Algebraic Geometry · Mathematics 2007-06-13 Nicholas Eriksson , Kristian Ranestad , Bernd Sturmfels , Seth Sullivant
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