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The advent of cost effective cloud computing over the past decade and ever-growing accumulation of high-fidelity clinical data in a modern hospital setting is leading to new opportunities for translational medicine. Machine learning is…

Databases · Computer Science 2021-06-09 Sanjay Malunjkar , Susan Weber , Somalee Datta

Machine learning-based approaches outperform competing methods in most disciplines relevant to diagnostic radiology. Interventional radiology, however, has not yet benefited substantially from the advent of deep learning, in particular…

It is now common to process volumetric biomedical images using 3D Convolutional Networks (ConvNets). This can be challenging for the teravoxel and even petavoxel images that are being acquired today by light or electron microscopy. Here we…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-03 Jingpeng Wu , William M. Silversmith , Kisuk Lee , H. Sebastian Seung

Multidimensional Big Data Analytics is an emerging area that marries the capabilities of OLAP with modern Big Data Analytics. Essentially, the idea is engrafting multidimensional models into Big Data analytics processes to gain into…

Databases · Computer Science 2024-07-29 Alfredo Cuzzocrea , Abderraouf Hafsaoui , Ismail Benlaredj

The distribution and interactions of cellular organelles play a critical role in mediating cellular physiology and pathology. Large-scale electron microscopy enables visualization of organelle distribution and interactions at the tissue…

Biological Physics · Physics 2026-02-24 Li Xiao , Liqing Liu , Hongjun Wu , Jiayi Zhong , Xixia Li , Yan Zhang , Junjie Hu , Sun Fei , Ge Yang , Tao Xu

The rise of mixed reality systems such as Microsoft HoloLens has prompted an increase in interest in the fields of 2D and 3D holography. Already applied in fields including telecommunications, imaging, projection, lithography, beam shaping…

Image and Video Processing · Electrical Eng. & Systems 2021-09-28 Peter J. Christopher , Andrew Kadis , George S. D. Gordon , Timothy D. Wilkinson

Analysis of genomics data is central to nearly all areas of modern biology. Despite significant progress in artificial intelligence (AI) and computational methods, these technologies require significant human oversight to generate novel and…

In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…

Image and Video Processing · Electrical Eng. & Systems 2022-02-03 Matthis Maillard , Anton François , Joan Glaunès , Isabelle Bloch , Pietro Gori

In the past decade, deep learning (DL) has achieved unprecedented success in numerous fields including computer vision, natural language processing, and healthcare. In particular, DL is experiencing an increasing development in applications…

Computer Vision and Pattern Recognition · Computer Science 2020-07-15 Liang Zhang , Johann Li , Ping Li , Xiaoyuan Lu , Peiyi Shen , Guangming Zhu , Syed Afaq Shah , Mohammed Bennarmoun , Kun Qian , Björn W. Schuller

The proliferation of open-source scientific software for science and research presents opportunities and challenges. In this paper, we introduce the SciCat dataset -- a comprehensive collection of Free-Libre Open Source Software (FLOSS)…

Software Engineering · Computer Science 2023-12-12 Addi Malviya-Thakur , Reed Milewicz , Lavinia Paganini , Ahmed Samir Imam Mahmoud , Audris Mockus

This paper presents HyperGraphOS, a significant innovation in the domain of operating systems, specifically designed to address the needs of scientific and engineering domains. This platform aims to combine model-based engineering, graph…

Software Engineering · Computer Science 2024-12-18 Antonello Ceravola , Frank Joublin

Higher Degree by Research (HDR) candidates increasingly depend on cloud-provisioned virtual machines and local GPU hardware for their computational experiments, yet a persistent and under-addressed gap exists between having compute…

Computational Engineering, Finance, and Science · Computer Science 2026-04-01 Bowen Li , Jiazhu Xie , Chelsea Wang , Alessandro Umberto D'Aloia , Ziqi Xu , Fengling Han

Motivation: Bioinformatics is faced with a variety of problems that require human involvement. Tasks like genome annotation, image analysis, knowledge-base construction and protein structure determination all benefit from human input. In…

Quantitative Methods · Quantitative Biology 2013-07-01 Benjamin M. Good , Andrew I. Su

Achieving precise, object-level control in image editing remains challenging: 2D methods lack 3D awareness and often yield ambiguous or implausible results, while existing 3D-aware approaches rely on heavy optimization or incomplete…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Yuhuan Xie , Aoxuan Pan , Yi-Hua Huang , Chirui Chang , Peng Dai , Xin Yu , Xiaojuan Qi

Multi-modal skin lesion diagnosis (MSLD) has achieved remarkable success by modern computer-aided diagnosis (CAD) technology based on deep convolutions. However, the information aggregation across modalities in MSLD remains challenging due…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yilan Zhang , Fengying Xie , Jianqi Chen

FPGAs have found their way into data centers as accelerator cards, making reconfigurable computing more accessible for high-performance applications. At the same time, new high-level synthesis compilers like Xilinx Vitis and runtime…

Hardware Architecture · Computer Science 2021-12-16 Puya Amiri , Arsène Pérard-Gayot , Richard Membarth , Philipp Slusallek , Roland Leißa , Sebastian Hack

Deformable image registration is one of the fundamental tasks in medical imaging. Classical registration algorithms usually require a high computational cost for iterative optimizations. Although deep-learning-based methods have been…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Boah Kim , Inhwa Han , Jong Chul Ye

Dense image segmentation tasks e.g., semantic, panoptic) are useful for image editing, but existing methods can hardly generalize well in an in-the-wild setting where there are unrestricted image domains, classes, and image resolution and…

Computer Vision and Pattern Recognition · Computer Science 2023-04-04 Lu Qi , Jason Kuen , Weidong Guo , Tiancheng Shen , Jiuxiang Gu , Jiaya Jia , Zhe Lin , Ming-Hsuan Yang

With the booming development of data science, many clustering methods have been proposed. All clustering methods have inherent merits and deficiencies. Therefore, they are only capable of clustering some specific types of data robustly. In…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Zhenzhou Wang

Open material databases storing hundreds of thousands of material structures and their corresponding properties have become the cornerstone of modern computational materials science. Yet, the raw outputs of the simulations, such as the…