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The increasing use of 3D imaging technologies in biological sciences is generating vast repositories of anatomical data, yet significant barriers prevent this data from reaching its full potential in educational and collaborative contexts.…

Quantitative Methods · Quantitative Biology 2026-01-05 A. Murat Maga , Steve Pieper , Cassandra Donatelli , Paul M Gignac , Matthew Kolmann , Christopher Noto , Adam Summers , Natalie Taft

Point clouds are a set of data points in space to represent the 3D geometry of objects. A fundamental step in the processing is to identify a subset of points to represent the shape. While traditional sampling methods often ignore to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-05 Pierre Onghena , Santiago Velasco-Forero , Beatriz Marcotegui

Although digital methods have significantly advanced morphology, practitioners are still challenged to understand and process tomographic specimen data. As automated processing of fossil data remains insufficient, morphologists still engage…

Human-Computer Interaction · Computer Science 2024-09-27 Lucas Siqueira Rodrigues , Thomas Kosch , John Nyakatura , Stefan Zachow , Johann Habakuk Israel

Collecting and annotating morphological data present significant challenges, requiring linguistic expertise, methodological rigour, and substantial resources. These barriers are particularly acute for low-resource languages and varieties.…

Computation and Language · Computer Science 2026-04-07 Aso Mahmudi , Sina Ahmadi , Kemal Kurniawan , Rico Sennrich , Eduard Hovy , Ekaterina Vylomova

Big data repositories from online learning platforms such as Massive Open Online Courses (MOOCs) represent an unprecedented opportunity to advance research on education at scale and impact a global population of learners. To date, such…

Software Engineering · Computer Science 2018-08-23 Josh Gardner , Christopher Brooks , Juan Miguel L. Andres , Ryan Baker

Cloud computing has the capacity to transform many parts of the research ecosystem, from particular research areas to overall strategic decision making and policy. Scientometrics sits at the boundary between research and the decision making…

Digital Libraries · Computer Science 2021-05-03 Daniel W Hook , Simon J Porter

With advanced imaging, sequencing, and profiling technologies, multiple omics data become increasingly available and hold promises for many healthcare applications such as cancer diagnosis and treatment. Multimodal learning for integrative…

Genomics · Quantitative Biology 2022-12-20 Sina Tabakhi , Mohammod Naimul Islam Suvon , Pegah Ahadian , Haiping Lu

The precise characterization of plant morphology provides valuable insights into plant environment interactions and genetic evolution. A key technology for extracting this information is 3D segmentation, which delineates individual plant…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Ruiming Du , Guangxun Zhai , Tian Qiu , Yu Jiang

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

Quantitative Methods · Quantitative Biology 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello

High-dimensional omics datasets are routinely visualized as heatmaps, where color intensities reveal co-expression patterns and correlations. However, modern omics technologies increasingly generate matrices so large that existing visual…

Genomics · Quantitative Biology 2026-04-21 Osho Rawal , Rex Lu , Edgar Gonzalez-Kozlova , Sacha Gnjatic , Zeynep H. Gümüş

Cloud computing provides a great opportunity for scientists, as it enables large-scale experiments that cannot are too long to run on local desktop machines. Cloud-based computations can be highly parallel, long running and data-intensive,…

Software Engineering · Computer Science 2016-12-07 Maria Spichkova , Heinz W. Schmidt , Ian E. Thomas , Iman I. Yusuf , Steve Androulakis , Grischa R. Meyer

In healthcare, accurately classifying medical images is vital, but conventional methods often hinge on medical data with a consistent grid structure, which may restrict their overall performance. Recent medical research has been focused on…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Kishore Babu Nampalle , Pradeep Singh , Vivek Narayan Uppala , Sumit Gangwar , Rajesh Singh Negi , Balasubramanian Raman

Deep learning methods have emerged as powerful tools for analyzing histopathological images, but current methods are often specialized for specific domains and software environments, and few open-source options exist for deploying models in…

The surge in high-throughput omics data has reshaped the landscape of biological research, underlining the need for powerful, user-friendly data analysis and interpretation tools. This paper presents GenoCraft, a web-based comprehensive…

Morphological profiling is a valuable tool in phenotypic drug discovery. The advent of high-throughput automated imaging has enabled the capturing of a wide range of morphological features of cells or organisms in response to perturbations…

Quantitative analysis of multidimensional biological images is useful for understanding complex cellular phenotypes and accelerating advances in biomedical research. As modern microscopy generates ever-larger 2D and 3D datasets, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-17 Alexandr A. Kalinin , Anne E. Carpenter , Shantanu Singh , Matthew J. O'Meara

Foundation models demand advanced data processing for their vast, multimodal datasets. However, traditional frameworks struggle with the unique complexities of multimodal data. In response, we present Data-Juicer 2.0, a data processing…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-30 Daoyuan Chen , Yilun Huang , Xuchen Pan , Nana Jiang , Haibin Wang , Yilei Zhang , Ce Ge , Yushuo Chen , Wenhao Zhang , Zhijian Ma , Jun Huang , Wei Lin , Yaliang Li , Bolin Ding , Jingren Zhou

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Zhongying Deng , Cheng Tang , Ziyan Huang , Jiashi Lin , Ying Chen , Junzhi Ning , Chenglong Ma , Jiyao Liu , Wei Li , Yinghao Zhu , Shujian Gao , Yanyan Huang , Sibo Ju , Yanzhou Su , Pengcheng Chen , Wenhao Tang , Tianbin Li , Haoyu Wang , Yuanfeng Ji , Hui Sun , Shaobo Min , Liang Peng , Feilong Tang , Haochen Xue , Rulin Zhou , Chaoyang Zhang , Wenjie Li , Shaohao Rui , Weijie Ma , Xingyue Zhao , Yibin Wang , Kun Yuan , Zhaohui Lu , Shujun Wang , Jinjie Wei , Lihao Liu , Dingkang Yang , Lin Wang , Yulong Li , Haolin Yang , Yiqing Shen , Lequan Yu , Xiaowei Hu , Yun Gu , Yicheng Wu , Benyou Wang , Minghui Zhang , Angelica I. Aviles-Rivero , Qi Gao , Hongming Shan , Xiaoyu Ren , Fang Yan , Hongyu Zhou , Haodong Duan , Maosong Cao , Shanshan Wang , Bin Fu , Xiaomeng Li , Zhi Hou , Chunfeng Song , Lei Bai , Yuan Cheng , Yuandong Pu , Xiang Li , Wenhai Wang , Hao Chen , Jiaxin Zhuang , Songyang Zhang , Huiguang He , Mengzhang Li , Bohan Zhuang , Zhian Bai , Rongshan Yu , Liansheng Wang , Yukun Zhou , Xiaosong Wang , Xin Guo , Guanbin Li , Xiangru Lin , Dakai Jin , Mianxin Liu , Wenlong Zhang , Qi Qin , Conghui He , Yuqiang Li , Ye Luo , Nanqing Dong , Jie Xu , Wenqi Shao , Bo Zhang , Qiujuan Yan , Yihao Liu , Jun Ma , Zhi Lu , Yuewen Cao , Zongwei Zhou , Jianming Liang , Shixiang Tang , Qi Duan , Dongzhan Zhou , Chen Jiang , Yuyin Zhou , Yanwu Xu , Jiancheng Yang , Shaoting Zhang , Xiaohong Liu , Siqi Luo , Yi Xin , Chaoyu Liu , Haochen Wen , Xin Chen , Alejandro Lozano , Min Woo Sun , Yuhui Zhang , Yue Yao , Xiaoxiao Sun , Serena Yeung-Levy , Xia Li , Jing Ke , Chunhui Zhang , Zongyuan Ge , Ming Hu , Jin Ye , Zhifeng Li , Yirong Chen , Yu Qiao , Junjun He

The storage and manipulation of digital images and the analysis of the information held in those images are essential requirements for next-generation medical information systems. The medical community has been exploring collaborative…

Databases · Computer Science 2007-05-23 D Rogulin , F Estrella , T Hauer , R McClatchey , T Solomonides

MRI-based medical imaging has become indispensable in modern clinical diagnosis, particularly for brain tumor detection. However, the rapid growth in data volume poses challenges for conventional diagnostic approaches. Although deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Hayder Saad Abdulbaqi , Mohammed Hadi Rahim , Mohammed Hassan Hadi , Haider Ali Aboud , Ali Hussein Allawi
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