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T2 hyperintensities in spinal cord MR images are crucial biomarkers for conditions such as degenerative cervical myelopathy. However, current clinical diagnoses primarily rely on manual evaluation. Deep learning methods have shown promise…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Kun Wang , Lianming Wu , Hongxing Shen , Jianqi Sun

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Existing anomaly detection (AD) methods often treat the modality and class as independent factors. Although this paradigm has enriched the development of AD research branches and produced many specialized models, it has also led to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuan Zhao , Youwei Pang , Lihe Zhang , Hanqi Liu , Jiaming Zuo , Huchuan Lu , Xiaoqi Zhao

We present a foundation model for brain MRI that can work with different combinations of imaging sequences. The model uses one encoder with learnable modality embeddings, conditional layer normalization, and a masked autoencoding objective…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Minh Sao Khue Luu , Bair N. Tuchinov

Vision foundation models like DINOv2 demonstrate remarkable potential in medical imaging despite their origin in natural image domains. However, their design inherently works best for uni-modal image analysis, limiting their effectiveness…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Viktoria Ehm , Anke Meyer-Baese , Jan C. Peeken , Daniel Rueckert , Benedikt Wiestler

Anomaly detection (AD) is a fundamental research problem in machine learning and computer vision, with practical applications in industrial inspection, video surveillance, and medical diagnosis. In medical imaging, AD is especially vital…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Jinan Bao , Hanshi Sun , Hanqiu Deng , Yinsheng He , Zhaoxiang Zhang , Xingyu Li

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Multimodal Industrial Anomaly Detection (MIAD), which utilizes 3D point clouds and 2D RGB images to identify abnormal regions in products, plays a crucial role in industrial quality inspection. However, traditional MIAD settings assume that…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Bingchen Miao , Wenqiao Zhang , Juncheng Li , Wangyu Wu , Siliang Tang , Zhaocheng Li , Haochen Shi , Jun Xiao , Yueting Zhuang

Normative modelling is an emerging method for understanding the underlying heterogeneity within brain disorders like Alzheimer Disease (AD) by quantifying how each patient deviates from the expected normative pattern that has been learned…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Sayantan Kumar , Philip Payne , Aristeidis Sotiras

In multi-class unsupervised anomaly detection(MUAD), reconstruction-based methods learn to map input images to normal patterns to identify anomalous pixels. However, this strategy easily falls into the well-known "learning shortcut" issue…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Jiajie Quan , Ao Tong , Yuxuan Cai , Xinwei He , Yulong Wang , Yang Zhou

While anomaly detection has made significant progress, generating detailed analyses that incorporate industrial knowledge remains a challenge. To address this gap, we introduce OmniAD, a novel framework that unifies anomaly detection and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Shifang Zhao , Yiheng Lin , Lu Han , Yao Zhao , Yunchao Wei

Unsupervised anomaly detection (UAD) has evolved from building specialized single-class models to unified multi-class models, yet existing multi-class models significantly underperform the most advanced one-for-one counterparts. Moreover,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Jia Guo , Shuai Lu , Lei Fan , Zelin Li , Donglin Di , Yang Song , Weihang Zhang , Wenbing Zhu , Hong Yan , Fang Chen , Huiqi Li , Hongen Liao

We propose a unified deep meta-learning framework for accelerated magnetic resonance imaging (MRI) that jointly addresses multi-coil reconstruction and cross-modality synthesis. Motivated by the limitations of conventional methods in…

Optimization and Control · Mathematics 2026-03-10 Merham Fouladvand , Peuroly Batra

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Georges El Fakhri , Jonghye Woo

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Medical Anomaly Detection (MedAD) presents a significant opportunity to enhance diagnostic accuracy using Large Multimodal Models (LMMs) to interpret and answer questions based on medical images. However, the reliance on Supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Haitao Zhang , Yingying Wang , Jiaxiang Wang , Haote Xu , Hongyang Zhang , Yirong Chen , Yue Huang , Xinghao Ding

Anomaly detection (AD) is a fundamental task of critical importance across numerous domains. Current systems increasingly operate in rapidly evolving environments that generate diverse yet interconnected data modalities -- such as time…

Machine Learning · Computer Science 2025-12-02 Zhongyuan Wu , Jingyuan Wang , Zexuan Cheng , Yilong Zhou , Weizhi Wang , Juhua Pu , Chao Li , Changqing Ma

Real-world industrial inspection requires not only localizing defects, but also explaining them in natural language and generating controlled defect edits. However, existing approaches fail to jointly support all three capabilities within a…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Haoyu Zheng , Tianwei Lin , Wei Wang , Zhuonan Wang , Wenqiao Zhang , Jiaqi Zhu , Feifei Shao

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

Image and Video Processing · Electrical Eng. & Systems 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima
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