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We present the Parallel, Forward-Backward with Pruning (PFBP) algorithm for feature selection (FS) in Big Data settings (high dimensionality and/or sample size). To tackle the challenges of Big Data FS PFBP partitions the data matrix both…

A major benefit of graphical models is that most knowledge is captured in the model structure. Many models, however, produce inference problems with a lot of symmetries not reflected in the graphical structure and hence not exploitable by…

Artificial Intelligence · Computer Science 2012-05-14 Kristian Kersting , Babak Ahmadi , Sriraam Natarajan

Microbes can affect processes from food production to human health. Such microbes are not isolated, but rather interact with each other and establish connections with their living environments. Understanding these interactions is essential…

Applications · Statistics 2021-09-07 Liang Chen , Qiuyan He , Hui Wan , Shun He , Minghua Deng

Dimension reduction of high-dimensional microbiome data facilitates subsequent analysis such as regression and clustering. Most existing reduction methods cannot fully accommodate the special features of the data such as count-valued and…

Methodology · Statistics 2023-05-02 Tianchen Xu , Ryan T. Demmer , Gen Li

Matrix factorisation methods decompose multivariate observations as linear combinations of latent feature vectors. The Indian Buffet Process (IBP) provides a way to model the number of latent features required for a good approximation in…

Machine Learning · Statistics 2017-04-14 Matthew C. Pearce , Simon R. White

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Learning physical dynamics from data is a fundamental challenge in machine learning and scientific modeling. Real-world observational data are inherently incomplete and irregularly sampled, posing significant challenges for existing…

Machine Learning · Computer Science 2026-05-04 Zihan Zhou , Chenguang Wang , Hongyi Ye , Yongtao Guan , Tianshu Yu

Predicting epidemic dynamics is of great value in understanding and controlling diffusion processes, such as infectious disease spread and information propagation. This task is intractable, especially when surveillance resources are very…

Machine Learning · Statistics 2017-12-04 Hongbin Pei , Bo Yang , Jiming Liu , Lei Dong

In low-resource settings, prevalence mapping relies on empirical prevalence data from a finite, often spatially sparse, set of surveys of communities within the region of interest, possibly supplemented by remotely sensed images that can…

Applications · Statistics 2015-05-27 Peter J. Diggle , Emanuele Giorgi

A general approach to selective inference is considered for hypothesis testing of the null hypothesis represented as an arbitrary shaped region in the parameter space of multivariate normal model. This approach is useful for hierarchical…

Statistics Theory · Mathematics 2018-03-28 Yoshikazu Terada , Hidetoshi Shimodaira

Spatial spread of infectious diseases among populations via the mobility of humans is highly stochastic and heterogeneous. Accurate forecast/mining of the spread process is often hard to be achieved by using statistical or mechanical…

Social and Information Networks · Computer Science 2016-11-18 Jian-Bo Wang , Lin Wang , Xiang Li

We consider the problem of statistical inference on parameters of a target population when auxiliary observations are available from related populations. We propose a flexible empirical Bayes approach that can be applied on top of any…

Statistics Theory · Mathematics 2023-12-15 Michael Law , Peter Bühlmann , Ya'acov Ritov

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

Methodology · Statistics 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

We propose a statistical learning framework based on group-sparse regression that can be used to 1) enforce conservation laws, 2) ensure model equivalence, and 3) guarantee symmetries when learning or inferring differential-equation models…

Machine Learning · Computer Science 2021-04-21 Suryanarayana Maddu , Bevan L. Cheeseman , Christian L. Müller , Ivo F. Sbalzarini

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Epidemic spreading often occurs in spatially heterogeneous environments, yet how quenched heterogeneity reshapes its onset and critical dynamics remains poorly understood. The diffusive epidemic process, a minimal reaction-diffusion model…

Statistical Mechanics · Physics 2026-03-24 Valentin Anfray , Hong-Yan Shih

Biological sequencing data consist of read counts, e.g. of specified taxa and often exhibit sparsity (zero-count inflation) and overdispersion (extra-Poisson variability). As most sequencing techniques provide an arbitrary total count,…

Applications · Statistics 2024-07-01 Noora Kartiosuo , Jaakko Nevalainen , Olli Raitakari , Katja Pahkala , Kari Auranen

One primary goal of human microbiome studies is to predict host traits based on human microbiota. However, microbial community sequencing data present significant challenges to the development of statistical methods. In particular, the…

Methodology · Statistics 2017-10-10 Tao Wang , Can Yang , Hongyu Zhao

Crowdsourcing systems enable us to collect large-scale dataset, but inherently suffer from noisy labels of low-paid workers. We address the inference and learning problems using such a crowdsourced dataset with noise. Due to the nature of…

Machine Learning · Computer Science 2022-02-25 Hoyoung Kim , Seunghyuk Cho , Dongwoo Kim , Jungseul Ok

High dimensional and heterogeneous count data are collected in various applied fields. In this paper, we look closely at high-resolution sequencing data on the microbiome, which have enabled researchers to study the genomes of entire…

Methodology · Statistics 2024-01-12 Veronica Vinciotti , Pariya Behrouzi , Reza Mohammadi